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O34499

- 6PGL_BACSU

UniProt

O34499 - 6PGL_BACSU

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Protein

6-phosphogluconolactonase

Gene
pgl, ykgB, BSU13010
Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.1 Publication

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.1 Publication

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciBSUB:BSU13010-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Gene namesi
Name:pgl
Synonyms:ykgB
Ordered Locus Names:BSU13010
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570: Chromosome

Organism-specific databases

GenoListiBSU13010. [Micado]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3493496-phosphogluconolactonasePRO_0000171144Add
BLAST

Proteomic databases

PaxDbiO34499.

Interactioni

Protein-protein interaction databases

IntActiO34499. 1 interaction.
MINTiMINT-8367251.
STRINGi224308.BSU13010.

Structurei

3D structure databases

ProteinModelPortaliO34499.
SMRiO34499. Positions 3-347.

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000243565.
KOiK07404.
OMAiPSPCHVS.
OrthoDBiEOG615VK7.
PhylomeDBiO34499.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR011048. Haem_d1.
IPR019405. Lactonase_7-beta_prop.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF51004. SSF51004. 1 hit.

Sequencei

Sequence statusi: Complete.

O34499-1 [UniParc]FASTAAdd to Basket

« Hide

MTKYIGYVGT YTKGGSEGIY SFELDTEKKA LSEPKLAAKL GNPTYVATNK    50
NNTILYSIEK ADGQGGVAAY QIDKNSGELT FLNHQLIDGP SPCHVSVDDQ 100
NQFVLTANYH SGKVHVFPVQ EDGSLQSPVS EAAHTGKGPH ERQEKPHTHY 150
AGFTPEHNYV VAVDLGIDKL YTYKLKDGVL TESGSHSFAP GAGPRHIAFH 200
PKEKYAYVMT ELSNEVIALE YNPTAGEFRE IQVVSAIPDD FTDNSQGSAI 250
HVTQDGRFVY VANRGHDSIA VFEVNQYSGE LAFVERVSTE GNWPRDFVFD 300
PTEGFLVASN EETGNLVLFE RDKETGRLTL LPSTVSVPYP VCVKFLHQV 349
Length:349
Mass (Da):38,411
Last modified:January 1, 1998 - v1
Checksum:iB8711D1D523CF5FF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ002571 Genomic DNA. Translation: CAA05581.1.
AL009126 Genomic DNA. Translation: CAB13158.1.
PIRiD69856.
RefSeqiNP_389184.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB13158; CAB13158; BSU13010.
GeneIDi937980.
KEGGibsu:BSU13010.
PATRICi18974359. VBIBacSub10457_1372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ002571 Genomic DNA. Translation: CAA05581.1 .
AL009126 Genomic DNA. Translation: CAB13158.1 .
PIRi D69856.
RefSeqi NP_389184.1. NC_000964.3.

3D structure databases

ProteinModelPortali O34499.
SMRi O34499. Positions 3-347.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O34499. 1 interaction.
MINTi MINT-8367251.
STRINGi 224308.BSU13010.

Proteomic databases

PaxDbi O34499.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB13158 ; CAB13158 ; BSU13010 .
GeneIDi 937980.
KEGGi bsu:BSU13010.
PATRICi 18974359. VBIBacSub10457_1372.

Organism-specific databases

GenoListi BSU13010. [Micado ]

Phylogenomic databases

eggNOGi COG2706.
HOGENOMi HOG000243565.
KOi K07404.
OMAi PSPCHVS.
OrthoDBi EOG615VK7.
PhylomeDBi O34499.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci BSUB:BSU13010-MONOMER.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR011048. Haem_d1.
IPR019405. Lactonase_7-beta_prop.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF10282. Lactonase. 1 hit.
[Graphical view ]
SUPFAMi SSF51004. SSF51004. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence of the Bacillus subtilis genome between xlyA and ykoR."
    Devine K.M.
    Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  3. "Global probabilistic annotation of metabolic networks enables enzyme discovery."
    Plata G., Fuhrer T., Sauer U., Vitkup D.
    Nat. Chem. Biol. 8:848-854(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, CATALYTIC ACTIVITY.

Entry informationi

Entry namei6PGL_BACSU
AccessioniPrimary (citable) accession number: O34499
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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