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O33921 (AGP_SALTY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-1-phosphatase

Short name=G1Pase
EC=3.1.3.10
Gene names
Name:agp
Ordered Locus Names:STM1117
OrganismSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP]
Taxonomic identifier99287 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length413 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.

Subunit structure

Homodimer By similarity.

Subcellular location

Periplasm.

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainSignal
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacid phosphatase activity

Inferred from electronic annotation. Source: InterPro

glucose-1-phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 By similarity
Chain23 – 413391Glucose-1-phosphatase
PRO_0000023949

Sites

Active site401Nucleophile By similarity
Active site3121Proton donor By similarity
Binding site391Substrate By similarity
Binding site431Substrate By similarity
Binding site1161Substrate By similarity
Binding site2181Substrate By similarity

Experimental info

Sequence conflict571T → P in AAC45604. Ref.2
Sequence conflict60 – 634AWPA → TCPP in AAC45604. Ref.2
Sequence conflict741K → T in AAC45604. Ref.2

Sequences

Sequence LengthMass (Da)Tools
O33921 [UniParc].

Last modified December 13, 2001. Version 2.
Checksum: E057667CF8A7244C

FASTA41345,559
        10         20         30         40         50         60 
MKKSLLAVAV AGAVLLSSAV QAQTTPEGYQ LQQVLMMSRH NLRAPLANNG SVLAQSTPNA 

        70         80         90        100        110        120 
WPAWDVPGGQ LTTKGGVLEV YMGHYTREWL VAQGLIPSGE CPAPDTVYAY ANSLQRTVAT 

       130        140        150        160        170        180 
AQFFITGAFP GCDIPVHHQE KMGTMDPTFN PVITDDSAAF RQQAVQAMEK ARSQLHLDES 

       190        200        210        220        230        240 
YKLLEQITHY QDSPSCKEKH QCSLIDAKDT FSANYQQEPG VQGPLKVGNS LVDAFTLQYY 

       250        260        270        280        290        300 
EGFPMDQVAW GGIHTDRQWK VLSKLKNGYQ DSLFTSPTVA RNVAAPLVKY IDKVLVADRV 

       310        320        330        340        350        360 
SAPKVTVLVG HDSNIASLLT ALDFKPYQLH DQYERTPIGG QLVFQRWHDG NANRDLMKIE 

       370        380        390        400        410 
YVYQSARQLR NAEALTLKSP AQRVTLELKG CPVDANGFCP LDKFDNVMNT AAK 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2."
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. expand/collapse author list , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.
Nature 413:852-856(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LT2 / SGSC1412 / ATCC 700720.
[2]"A Salmonella typhimurium genetic locus which confers copper tolerance on copper-sensitive mutants of Escherichia coli."
Gupta S.D., Wu H.C., Rick P.D.
J. Bacteriol. 179:4977-4984(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-249.
Strain: TN1379.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006468 Genomic DNA. Translation: AAL20049.1.
U75949 Genomic DNA. Translation: AAC45604.1.
RefSeqNP_460090.1. NC_003197.1.

3D structure databases

ProteinModelPortalO33921.
SMRO33921. Positions 23-413.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING99287.STM1117.

Proteomic databases

PaxDbO33921.
PRIDEO33921.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL20049; AAL20049; STM1117.
GeneID1252635.
KEGGstm:STM1117.
PATRIC32380673. VBISalEnt20916_1182.

Phylogenomic databases

eggNOGNOG28269.
HOGENOMHOG000118851.
KOK01085.
OMAFQRWHDK.
OrthoDBEOG64N9T2.
ProtClustDBPRK10173.

Enzyme and pathway databases

BioCycSENT99287:GCTI-1126-MONOMER.

Family and domain databases

InterProIPR000560. His_Pase_superF_clade-2.
[Graphical view]
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAGP_SALTY
AccessionPrimary (citable) accession number: O33921
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: December 13, 2001
Last modified: April 16, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families