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O33815 (BGAL_STAXY) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-galactosidase

Short name=Beta-gal
EC=3.2.1.23
Alternative name(s):
Lactase
Gene names
Name:lacZ
Synonyms:lacH
OrganismStaphylococcus xylosus
Taxonomic identifier1288 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length994 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sequence similarities

Belongs to the glycosyl hydrolase 2 family.

Ontologies

Keywords
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentbeta-galactosidase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

carbohydrate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 994994Beta-galactosidase
PRO_0000057675

Sites

Active site4371Proton donor By similarity
Active site5101Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
O33815 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 78B2B43EB3EE0B1B

FASTA994115,234
        10         20         30         40         50         60 
MLKQQFHENL EVQHVNLLPR RAFYIPYQQG EADYHFETRY NTRNATLLNG EWYFQYFESL 

        70         80         90        100        110        120 
EAYLNHSNKQ ESKTLTVPSV WNLYGYDQIQ YLNTQYPIPF NPPYVPKDNP CGHYTRKFTI 

       130        140        150        160        170        180 
DEYDQQYDYH LNFEGVDSAF YVWINNEFIG YSQISHAISE FDISNFVKQG ENNIEVLVLK 

       190        200        210        220        230        240 
YSDGTYLEDQ DMFRHSGIFR DVYILKRATE RVDDFKVETN LSDDLNAAQI DVKIERAHNL 

       250        260        270        280        290        300 
KSVEFQLYNP KGEEVASISG VNEHQFDVHN PHLWSTENPV LYTLYILTDQ EVITQKVGIR 

       310        320        330        340        350        360 
EVAIQNNQFY INGQSIKIRG TNYHDSHPET GYVMTESHFK KDLELMKQGN FNAIRTAHYP 

       370        380        390        400        410        420 
KSPLFYEMTD QYGFYVMSEA DIETHGVVRL YGEDNNEDFN IIADDSKFET AIIERIEASI 

       430        440        450        460        470        480 
MPLKNYSSIV SWSLGNESGF GKNMVKGAAR AKSLDNTRPI HYEGTLYRDK QQHYDLSNID 

       490        500        510        520        530        540 
MISRMYPSPE EIEETYLSNP DLDKPFILCE YAHAMGNSPG DLHAYQTLVE QYDSFIGGFV 

       550        560        570        580        590        600 
WEWCDHAIQT GMKDGNPIFR YGGDFGEKLH DGNFCVDGIV FPNRVPHEGY YEFKQEHRPL 

       610        620        630        640        650        660 
NLVSQEDFKI VLRNQLDFIP AEKYMFVEAT VTNLNGGKTI SEIPLSNFLP HTAQTIDLSD 

       670        680        690        700        710        720 
YINIQHISDV ILRYKLKYDD IFRHENFELG HDQIVYQRRT LKEQNEQSDE TEILVTQTDK 

       730        740        750        760        770        780 
LIKVSVGKSE TYVFNKDNAS LESVLKHNHI VISQNTTNNI WRAPTDNDTN IKNDWAYSGY 

       790        800        810        820        830        840 
KDITTRVHDY QIVENETEVS LIFNIAMVND AVPPVLFGTV TWHVQRNGTL NVTYDLERDM 

       850        860        870        880        890        900 
KAPYLPRFGL GLTLPKAFEQ VKYYGKGPFS SYQDKGVANY LDDFGTTVTD NGEIHIRPQE 

       910        920        930        940        950        960 
TGSHNETTFV EISDGCKKVI VTSDNTFSFN TTHYSLKQLT ETTHKDALEP EDQTYLYIDY 

       970        980        990 
AQSGIGSNSC GPELNEAYRL NNRHIEFSFN LKFV 

« Hide

References

[1]"Regulation of lactose utilization genes in Staphylococcus xylosus."
Bassias J., Brueckner R.
J. Bacteriol. 180:2273-2279(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: DSM 20267 / Isolate C2A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y14599 Genomic DNA. Translation: CAA74937.1.

3D structure databases

ProteinModelPortalO33815.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.120.260. 1 hit.
2.60.40.320. 1 hit.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSPR00132. GLHYDRLASE2.
SMARTSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMSSF49303. SSF49303. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGAL_STAXY
AccessionPrimary (citable) accession number: O33815
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: October 16, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries