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O33815

- BGAL_STAXY

UniProt

O33815 - BGAL_STAXY

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Protein

Beta-galactosidase

Gene

lacZ

Organism
Staphylococcus xylosus
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei437 – 4371Proton donorBy similarity
Active sitei510 – 5101NucleophileBy similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase (EC:3.2.1.23)
Short name:
Beta-gal
Alternative name(s):
Lactase
Gene namesi
Name:lacZ
Synonyms:lacH
OrganismiStaphylococcus xylosus
Taxonomic identifieri1288 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 994994Beta-galactosidasePRO_0000057675Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO33815.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.Curated

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 1 hit.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O33815-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLKQQFHENL EVQHVNLLPR RAFYIPYQQG EADYHFETRY NTRNATLLNG
60 70 80 90 100
EWYFQYFESL EAYLNHSNKQ ESKTLTVPSV WNLYGYDQIQ YLNTQYPIPF
110 120 130 140 150
NPPYVPKDNP CGHYTRKFTI DEYDQQYDYH LNFEGVDSAF YVWINNEFIG
160 170 180 190 200
YSQISHAISE FDISNFVKQG ENNIEVLVLK YSDGTYLEDQ DMFRHSGIFR
210 220 230 240 250
DVYILKRATE RVDDFKVETN LSDDLNAAQI DVKIERAHNL KSVEFQLYNP
260 270 280 290 300
KGEEVASISG VNEHQFDVHN PHLWSTENPV LYTLYILTDQ EVITQKVGIR
310 320 330 340 350
EVAIQNNQFY INGQSIKIRG TNYHDSHPET GYVMTESHFK KDLELMKQGN
360 370 380 390 400
FNAIRTAHYP KSPLFYEMTD QYGFYVMSEA DIETHGVVRL YGEDNNEDFN
410 420 430 440 450
IIADDSKFET AIIERIEASI MPLKNYSSIV SWSLGNESGF GKNMVKGAAR
460 470 480 490 500
AKSLDNTRPI HYEGTLYRDK QQHYDLSNID MISRMYPSPE EIEETYLSNP
510 520 530 540 550
DLDKPFILCE YAHAMGNSPG DLHAYQTLVE QYDSFIGGFV WEWCDHAIQT
560 570 580 590 600
GMKDGNPIFR YGGDFGEKLH DGNFCVDGIV FPNRVPHEGY YEFKQEHRPL
610 620 630 640 650
NLVSQEDFKI VLRNQLDFIP AEKYMFVEAT VTNLNGGKTI SEIPLSNFLP
660 670 680 690 700
HTAQTIDLSD YINIQHISDV ILRYKLKYDD IFRHENFELG HDQIVYQRRT
710 720 730 740 750
LKEQNEQSDE TEILVTQTDK LIKVSVGKSE TYVFNKDNAS LESVLKHNHI
760 770 780 790 800
VISQNTTNNI WRAPTDNDTN IKNDWAYSGY KDITTRVHDY QIVENETEVS
810 820 830 840 850
LIFNIAMVND AVPPVLFGTV TWHVQRNGTL NVTYDLERDM KAPYLPRFGL
860 870 880 890 900
GLTLPKAFEQ VKYYGKGPFS SYQDKGVANY LDDFGTTVTD NGEIHIRPQE
910 920 930 940 950
TGSHNETTFV EISDGCKKVI VTSDNTFSFN TTHYSLKQLT ETTHKDALEP
960 970 980 990
EDQTYLYIDY AQSGIGSNSC GPELNEAYRL NNRHIEFSFN LKFV
Length:994
Mass (Da):115,234
Last modified:January 1, 1998 - v1
Checksum:i78B2B43EB3EE0B1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14599 Genomic DNA. Translation: CAA74937.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14599 Genomic DNA. Translation: CAA74937.1 .

3D structure databases

ProteinModelPortali O33815.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.320. 1 hit.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProi IPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view ]
PRINTSi PR00132. GLHYDRLASE2.
SMARTi SM01038. Bgal_small_N. 1 hit.
[Graphical view ]
SUPFAMi SSF49303. SSF49303. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEi PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Regulation of lactose utilization genes in Staphylococcus xylosus."
    Bassias J., Brueckner R.
    J. Bacteriol. 180:2273-2279(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DSM 20267 / Isolate C2A.

Entry informationi

Entry nameiBGAL_STAXY
AccessioniPrimary (citable) accession number: O33815
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: October 1, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3