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O33815

- BGAL_STAXY

UniProt

O33815 - BGAL_STAXY

Protein

Beta-galactosidase

Gene

lacZ

Organism
Staphylococcus xylosus
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei437 – 4371Proton donorBy similarity
    Active sitei510 – 5101NucleophileBy similarity

    GO - Molecular functioni

    1. beta-galactosidase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Protein family/group databases

    CAZyiGH2. Glycoside Hydrolase Family 2.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-galactosidase (EC:3.2.1.23)
    Short name:
    Beta-gal
    Alternative name(s):
    Lactase
    Gene namesi
    Name:lacZ
    Synonyms:lacH
    OrganismiStaphylococcus xylosus
    Taxonomic identifieri1288 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

    Subcellular locationi

    GO - Cellular componenti

    1. beta-galactosidase complex Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 994994Beta-galactosidasePRO_0000057675Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO33815.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 2 family.Curated

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    2.60.40.320. 1 hit.
    2.70.98.10. 1 hit.
    3.20.20.80. 1 hit.
    InterProiIPR004199. B-gal_small/dom_5.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR008979. Galactose-bd-like.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR006101. Glyco_hydro_2.
    IPR013812. Glyco_hydro_2/20_Ig-like.
    IPR023232. Glyco_hydro_2_AS.
    IPR023230. Glyco_hydro_2_CS.
    IPR006102. Glyco_hydro_2_Ig-like.
    IPR006104. Glyco_hydro_2_N.
    IPR006103. Glyco_hydro_2_TIM.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF02929. Bgal_small_N. 1 hit.
    PF00703. Glyco_hydro_2. 1 hit.
    PF02836. Glyco_hydro_2_C. 1 hit.
    PF02837. Glyco_hydro_2_N. 1 hit.
    [Graphical view]
    PRINTSiPR00132. GLHYDRLASE2.
    SMARTiSM01038. Bgal_small_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF49303. SSF49303. 1 hit.
    SSF49785. SSF49785. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF74650. SSF74650. 1 hit.
    PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
    PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O33815-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKQQFHENL EVQHVNLLPR RAFYIPYQQG EADYHFETRY NTRNATLLNG    50
    EWYFQYFESL EAYLNHSNKQ ESKTLTVPSV WNLYGYDQIQ YLNTQYPIPF 100
    NPPYVPKDNP CGHYTRKFTI DEYDQQYDYH LNFEGVDSAF YVWINNEFIG 150
    YSQISHAISE FDISNFVKQG ENNIEVLVLK YSDGTYLEDQ DMFRHSGIFR 200
    DVYILKRATE RVDDFKVETN LSDDLNAAQI DVKIERAHNL KSVEFQLYNP 250
    KGEEVASISG VNEHQFDVHN PHLWSTENPV LYTLYILTDQ EVITQKVGIR 300
    EVAIQNNQFY INGQSIKIRG TNYHDSHPET GYVMTESHFK KDLELMKQGN 350
    FNAIRTAHYP KSPLFYEMTD QYGFYVMSEA DIETHGVVRL YGEDNNEDFN 400
    IIADDSKFET AIIERIEASI MPLKNYSSIV SWSLGNESGF GKNMVKGAAR 450
    AKSLDNTRPI HYEGTLYRDK QQHYDLSNID MISRMYPSPE EIEETYLSNP 500
    DLDKPFILCE YAHAMGNSPG DLHAYQTLVE QYDSFIGGFV WEWCDHAIQT 550
    GMKDGNPIFR YGGDFGEKLH DGNFCVDGIV FPNRVPHEGY YEFKQEHRPL 600
    NLVSQEDFKI VLRNQLDFIP AEKYMFVEAT VTNLNGGKTI SEIPLSNFLP 650
    HTAQTIDLSD YINIQHISDV ILRYKLKYDD IFRHENFELG HDQIVYQRRT 700
    LKEQNEQSDE TEILVTQTDK LIKVSVGKSE TYVFNKDNAS LESVLKHNHI 750
    VISQNTTNNI WRAPTDNDTN IKNDWAYSGY KDITTRVHDY QIVENETEVS 800
    LIFNIAMVND AVPPVLFGTV TWHVQRNGTL NVTYDLERDM KAPYLPRFGL 850
    GLTLPKAFEQ VKYYGKGPFS SYQDKGVANY LDDFGTTVTD NGEIHIRPQE 900
    TGSHNETTFV EISDGCKKVI VTSDNTFSFN TTHYSLKQLT ETTHKDALEP 950
    EDQTYLYIDY AQSGIGSNSC GPELNEAYRL NNRHIEFSFN LKFV 994
    Length:994
    Mass (Da):115,234
    Last modified:January 1, 1998 - v1
    Checksum:i78B2B43EB3EE0B1B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y14599 Genomic DNA. Translation: CAA74937.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y14599 Genomic DNA. Translation: CAA74937.1 .

    3D structure databases

    ProteinModelPortali O33815.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH2. Glycoside Hydrolase Family 2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    2.60.40.320. 1 hit.
    2.70.98.10. 1 hit.
    3.20.20.80. 1 hit.
    InterProi IPR004199. B-gal_small/dom_5.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR008979. Galactose-bd-like.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR006101. Glyco_hydro_2.
    IPR013812. Glyco_hydro_2/20_Ig-like.
    IPR023232. Glyco_hydro_2_AS.
    IPR023230. Glyco_hydro_2_CS.
    IPR006102. Glyco_hydro_2_Ig-like.
    IPR006104. Glyco_hydro_2_N.
    IPR006103. Glyco_hydro_2_TIM.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF02929. Bgal_small_N. 1 hit.
    PF00703. Glyco_hydro_2. 1 hit.
    PF02836. Glyco_hydro_2_C. 1 hit.
    PF02837. Glyco_hydro_2_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00132. GLHYDRLASE2.
    SMARTi SM01038. Bgal_small_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49303. SSF49303. 1 hit.
    SSF49785. SSF49785. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF74650. SSF74650. 1 hit.
    PROSITEi PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
    PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Regulation of lactose utilization genes in Staphylococcus xylosus."
      Bassias J., Brueckner R.
      J. Bacteriol. 180:2273-2279(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: DSM 20267 / Isolate C2A.

    Entry informationi

    Entry nameiBGAL_STAXY
    AccessioniPrimary (citable) accession number: O33815
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3