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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Streptomyces lividans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2
Alternative name(s):
Protein Cpn60 2
groEL2 protein
Gene namesi
Name:groL2
Synonyms:groEL2
OrganismiStreptomyces lividans
Taxonomic identifieri1916 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000635542 – 47760 kDa chaperonin 2Add BLAST476

Proteomic databases

PRIDEiO33658

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.By similarity

Structurei

3D structure databases

ProteinModelPortaliO33658
SMRiO33658
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.Curated

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O33658-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKIIAFDEK ARRGLEGGMN QLADAVKVTL GPKGRNVVLE KKWGAPTITN
60 70 80 90 100
DGVSIAKEIE LEDPYEKIGA ELVKEVAKKT DDVAGDGTTT ATVLAQALVK
110 120 130 140 150
EGLRNVAAGA NPMALKRGIE KAVEAVSGAL LEQAKDVETK EQIASTASIS
160 170 180 190 200
AADTQIGELI AEAMDKVGKE GVITVEEFQT FGLELELTEG MGFDKGYISA
210 220 230 240 250
YFATDMERME ASLDDPYILI ANSKIGNVKD LLPLLEKVMQ SGKPLLIIAE
260 270 280 290 300
DVEGEALSTL VVNKIRGTFK SVAVKAPGFG DRRKAMLGDI AILTGGEVIS
310 320 330 340 350
EEVGLKLENA GLDLLGRARK VVITKDETTI VDGAGDTDQV NGRVAQIRAE
360 370 380 390 400
IENSDSDYDR EKLQERLANV AGGVAVIKAG AATEVELKER KERKHRIEDA
410 420 430 440 450
VRNAKAAVEE GIVAGGGVAL LQASQVFEKL ELTGDEATGA NAVKLALEAP
460 470
LKQIPSTAVS RAAWSWRRCA TSPWATA
Length:477
Mass (Da):50,661
Last modified:January 23, 2007 - v3
Checksum:i2BAEA494832A628C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95971 Genomic DNA Translation: CAA65226.1

Similar proteinsi

Entry informationi

Entry nameiCH602_STRLI
AccessioniPrimary (citable) accession number: O33658
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 87 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health