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Protein
Submitted name:

Putative P-type cation-translocating membrane ATPase

Gene

ppaA

Organism
Proteus mirabilis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi3PROSITE-ProRule annotation1
Metal bindingi6PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative P-type cation-translocating membrane ATPaseImported
Gene namesi
Name:ppaAImported
OrganismiProteus mirabilisImported
Taxonomic identifieri584 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaeProteus

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei69 – 89HelicalUniRule annotationAdd BLAST21
Transmembranei95 – 113HelicalUniRule annotationAdd BLAST19
Transmembranei125 – 142HelicalUniRule annotationAdd BLAST18
Transmembranei148 – 167HelicalUniRule annotationAdd BLAST20
Transmembranei298 – 319HelicalUniRule annotationAdd BLAST22
Transmembranei325 – 349HelicalUniRule annotationAdd BLAST25
Transmembranei639 – 664HelicalUniRule annotationAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliO33448.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 55HMAInterPro annotationAdd BLAST55

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C59. Bacteria.
COG2217. LUCA.

Family and domain databases

CDDicd00371. HMA. 1 hit.
Gene3Di3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
InterProiView protein in InterPro
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006121. HMA_dom.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
PfamiView protein in Pfam
PF00403. HMA. 1 hit.
PRINTSiPR00941. CDATPASE.
SUPFAMiSSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
SSF81653. SSF81653. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.
PS50846. HMA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O33448-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDCPTCAQKI ETAVLKVVGV KQAKILFATE KLVVDADIRT DVISAVKSAG
60 70 80 90 100
FELFDISSAG SQPPAKQSLL KESSFVIILA ILMAISWGAE FIDPQAGRAA
110 120 130 140 150
FIATTLIGLF PIVKKLLRLI RSGTPFAIET LMSVAAIGAL FINATEEAAM
160 170 180 190 200
VILLFMIGEM LESYAAGRAR RGVSALMALV PEEAVVIKEG KKQTVPVAQL
210 220 230 240 250
RPGDIIEIAP GRALPTDAEL ITAFASFDES ALTGESVPVE RLQGEKVAAG
260 270 280 290 300
CLSVDRSVQM KVVSEQGQNA IDRILQLIEE AEERKAPIER FVDRFSRYYT
310 320 330 340 350
PLIMLFSALV IIIPPLLFAQ PWETWFYRGL TLLLIGCPCA LVISTPAAIT
360 370 380 390 400
SALAAATKRG ALIKGGAALE QLGTVNTVAL DKTGTLTEGK PQVTDVIANV
410 420 430 440 450
GFNEKELLML ASSVEVGSHH PLAKAIINKA QEQQIDVVEA DNRKALAGKG
460 470 480 490 500
IEGYLNNQHI LVSAPTQLSE TIPLSAQWQQ QVARLEDEGK TVVVVLKEDQ
510 520 530 540 550
FIGVIAMQDT LRNDAIESMK EKKVLKSMNI NAVMLTGDNP RAAAAIAQKL
560 570 580 590 600
GMDFRAGLLP EDKVTSVMEI SQTHNTMMVG DGINDAPAMK AATIGVAMGS
610 620 630 640 650
GTDVALETAD AALTHNRLTG LPEIIQLSRA TRKIIRENIT IALGLKAIFL
660 670 680 690
VTSLFGITGL WVAVLADSGA TALVTANAVR LLKVKLKSPH QD
Length:692
Mass (Da):73,950
Last modified:January 1, 1998 - v1
Checksum:i5750F9E005305E8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001437 Genomic DNA. Translation: CAA04762.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO33448_PROMI
AccessioniPrimary (citable) accession number: O33448
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 5, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)