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Protein
Submitted name:

Possible transcriptional regulatory protein

Gene

Rv0339c

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Possible transcriptional regulatory proteinImported
Submitted name:
Transcriptional regulatorImported
Gene namesi
Ordered Locus Names:Rv0339cImported
ORF Names:LH57_01840Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv0339c.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0339c.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini756 – 82166HTH luxR-type DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH luxR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105XYI. Bacteria.
COG2771. LUCA.
HOGENOMiHOG000074603.
OMAiIYISPRT.
OrthoDBiEOG69GZGV.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O33269-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQHRGCKNRG QAYDASVTDS LTEVPPAARR ALLELANAPT VPVKVLITGG
60 70 80 90 100
IGTGKTTVLA AARDTLRRSG LTVLACPPPD GEPPETALVI DDAQLLTDTE
110 120 130 140 150
LLRLTERVAD SRLTVVAAAE AREHHRALRA LTMALERDRP RISLGPLPVA
160 170 180 190 200
EHLRDCTAGL PFLIHAVSAR AQAPAQAAKV ALIERLRRLD EPTLDTLLMM
210 220 230 240 250
SLTHELGVSD VAAALGISVT DARGLVDRAH ASGLIESSHT AAFLQSVHDA
260 270 280 290 300
IAQIVGNAHH HEVETSLLRS QLDISPVSAE LALRLAEHGL RDERLADILT
310 320 330 340 350
RYAADTRDAS VRCARLYRAA VHAGAKGLTV RLADALARTG DCTAAATLAD
360 370 380 390 400
DLLSSPDATE RAAAVRVAAS VAVHDGNTGH AAELFGWLGP HPDTMVSSAA
410 420 430 440 450
TIVFAANGDL ATARATLRLK DAGPPTMAAR CARNLAEGLL LTMDQPYPVA
460 470 480 490 500
MAKLGQAIAT EQSLSQVIPD SPAALVTLAA IHAGDPVRAR SVIGRAVRAG
510 520 530 540 550
ADPLFQRRHL LLSGWIKMQE GQLPSASADV AAASAGTHLH RRDALWAAAL
560 570 580 590 600
QTAISRRTGD IGALQQHWYA AMEALAEYSL DLFALLPLGE LWVAAARMRQ
610 620 630 640 650
VDQLQHTLDQ ALTLLDSLGN PALWSNSLHW AGVHAGILAN SPESVAPHGQ
660 670 680 690 700
ALGAMVAHST LAQALSDAGR TWLRVLAENV DADEVTAAAR SLSHVGLTSD
710 720 730 740 750
ATRLAGQAAL QTSDARVSGA MLQLARDLKL GNDFGEPPSG AGDTEPASGT
760 770 780 790 800
PPAPRQPPAG SPLSDREREV AELLLLGMPY RDIGARLFIS AKTVEHHVAR
810 820 830
IRQRLGAGSR SEMLSMLRAM LAPESLTADE RR
Length:832
Mass (Da):87,776
Last modified:January 1, 1998 - v1
Checksum:i4F6C8CCCE8706A3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13061.1.
AL123456 Genomic DNA. Translation: CCP43069.1.
RefSeqiNP_214853.1. NC_000962.3.
WP_003401735.1. NC_000962.3.

Genome annotation databases

EnsemblBacteriaiAIR13061; AIR13061; LH57_01840.
CCP43069; CCP43069; Rv0339c.
GeneIDi886516.
KEGGimtu:Rv0339c.
mtv:RVBD_0339c.
PATRICi18122488. VBIMycTub22151_0378.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR13061.1.
AL123456 Genomic DNA. Translation: CCP43069.1.
RefSeqiNP_214853.1. NC_000962.3.
WP_003401735.1. NC_000962.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0339c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR13061; AIR13061; LH57_01840.
CCP43069; CCP43069; Rv0339c.
GeneIDi886516.
KEGGimtu:Rv0339c.
mtv:RVBD_0339c.
PATRICi18122488. VBIMycTub22151_0378.

Organism-specific databases

TubercuListiRv0339c.

Phylogenomic databases

eggNOGiENOG4105XYI. Bacteria.
COG2771. LUCA.
HOGENOMiHOG000074603.
OMAiIYISPRT.
OrthoDBiEOG69GZGV.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27294 / TMC 102 / H37RvImported and H37RvImported.

Entry informationi

Entry nameiO33269_MYCTU
AccessioniPrimary (citable) accession number: O33269
Secondary accession number(s): F2GN29, I6X904, Q7D9Z8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.