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Protein
Submitted name:

TetR family transcriptional regulator

Gene

Rv1685c

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi41 – 60H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TetR family transcriptional regulatorImported
Gene namesi
Ordered Locus Names:Rv1685cImported
ORF Names:LH57_09185Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1685c.

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1685c.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 78HTH tetR-type DNA-bindingInterPro annotationAdd BLAST61

Phylogenomic databases

eggNOGiENOG4108ZNU. Bacteria.
ENOG4111QBX. LUCA.
HOGENOMiHOG000021524.
OMAiLELEPFK.

Family and domain databases

Gene3Di1.10.357.10. 2 hits.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
PfamiView protein in Pfam
PF00440. TetR_N. 1 hit.
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiView protein in PROSITE
PS50977. HTH_TETR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O33187-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPDNSRRR PGRPAGSSDT RERILSSARE LFAHNGIDRT SIRAVAAKAG
60 70 80 90 100
VDAALVHHYF GTKQQLFAAA IHIPIDPMVI IGPIREAPVE ELGYKLPSLL
110 120 130 140 150
LPIWDSELGA GLIATLRSLI SGSDVGLARS FLEEVVTVEL GSRVDNPPGT
160 170 180 190 200
GKIRTQFVAS QLMGVVMARY IVRIEPFASL PAEQIVQTIA PNLQRYLTGE

LPDDLAP
Length:207
Mass (Da):22,324
Last modified:January 1, 1998 - v1
Checksum:i28F8AC74F796CAAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14436.1.
AL123456 Genomic DNA. Translation: CCP44450.1.
RefSeqiNP_216201.1. NC_000962.3.
WP_003408366.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR14436; AIR14436; LH57_09185.
CCP44450; CCP44450; Rv1685c.
GeneIDi885682.
KEGGimtu:Rv1685c.
mtv:RVBD_1685c.
PATRICi18125546. VBIMycTub22151_1887.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14436.1.
AL123456 Genomic DNA. Translation: CCP44450.1.
RefSeqiNP_216201.1. NC_000962.3.
WP_003408366.1. NZ_KK339370.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1685c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR14436; AIR14436; LH57_09185.
CCP44450; CCP44450; Rv1685c.
GeneIDi885682.
KEGGimtu:Rv1685c.
mtv:RVBD_1685c.
PATRICi18125546. VBIMycTub22151_1887.

Organism-specific databases

TubercuListiRv1685c.

Phylogenomic databases

eggNOGiENOG4108ZNU. Bacteria.
ENOG4111QBX. LUCA.
HOGENOMiHOG000021524.
OMAiLELEPFK.

Family and domain databases

Gene3Di1.10.357.10. 2 hits.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
PfamiView protein in Pfam
PF00440. TetR_N. 1 hit.
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiView protein in PROSITE
PS50977. HTH_TETR_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO33187_MYCTU
AccessioniPrimary (citable) accession number: O33187
Secondary accession number(s): F2GK52, I6X201, Q7D854
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: February 15, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.