O33002 (RL15_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L15

Gene names

Name:	rplO
Ordered Locus Names:	ML1840
ORF Names:	MLCB2492.23

Organism

Mycobacterium leprae [Complete proteome] [HAMAP]

Taxonomic identifier

1769 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	146 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the 23S rRNA By similarity. HAMAP MF_01341_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L15P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 146	146	50S ribosomal protein L15 HAMAP MF_01341_B		PRO_0000104753

Sequences

	Sequence		Length	Mass (Da)
	O33002 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 7941A159C4611ED4	FASTA	146	15,729
	10 20 30 40 50 60 MTIKLHDLQP ARGSKTTRTR VGRGEASKGK TAGRGTKGTK ARKQVPVTFE GGQMPIHMRL 70 80 90 100 110 120 PKLKGFRNRL RTEYAVVNVG DISRLFPEGG TISVNDLVAK KAIRKNSLVK ILGDGKLTVK 130 140 VTLSAHKFSG SARHKITVAG GSVTEL

References

[1]

"Massive gene decay in the leprosy bacillus." Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E., Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., Duthoy S. , Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S., Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R., Barrell B.G. Nature 409:1007-1011(2001) [PubMed: 11234002] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TN.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z98756 Genomic DNA. Translation: CAB11455.1. AL583923 Genomic DNA. Translation: CAC30794.1.
PIR	T45385.
RefSeq	NP_302246.1. NC_002677.1.
3D structure databases
ProteinModelPortal	O33002.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000028332; EBMYCP00000027938; EBMYCG00000028327.
GeneID	910650.
GenomeReviews	Gene locus ML1840 in contig AL450380_GR.
KEGG	mle:ML1840.
NMPDR	fig|272631.1.peg.1118.
PATRIC	18057126. VBIMycLep78757_3490.
Organism-specific databases
Leproma	ML1840.
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017661.
HOGENOM	HBG727142.
OMA	RKGRGHA.
ProtClustDB	PRK05592.
Enzyme and pathway databases
BioCyc	MLEP272631:ML1840-MONOMER.
Family and domain databases
HAMAP	MF_01341_B. Ribosomal_L15_B. [Tree]
InterPro	IPR005749. Ribosomal_L15_bac-type. IPR001196. Ribosomal_L15_CS. IPR021131. Ribosomal_L18e/L15P. [Graphical view]
KO	K02876.
PANTHER	PTHR12934. Ribosom_L15_bac. 1 hit.
Pfam	PF00828. Ribosomal_L18e. 1 hit. [Graphical view]
SUPFAM	SSF52080. Ribosomal_L18e/L15. 1 hit.
TIGRFAMs	TIGR01071. RplO_bact. 1 hit.
PROSITE	PS00475. RIBOSOMAL_L15. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL15_MYCLE

Accession

Primary (citable) accession number: O33002

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	January 1, 1998
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program