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Protein

50S ribosomal protein L6

Gene

rplF

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L6UniRule annotation
Gene namesi
Name:rplFUniRule annotation
Ordered Locus Names:ML1844
ORF Names:MLCB2492.19
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000806 Componenti: Chromosome

Organism-specific databases

LepromaiML1844.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 17917950S ribosomal protein L6PRO_0000131060Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi272631.ML1844.

Structurei

3D structure databases

ProteinModelPortaliO32998.
SMRiO32998. Positions 8-179.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L6P family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R5J. Bacteria.
COG0097. LUCA.
HOGENOMiHOG000039903.
KOiK02933.
OMAiLIANMVE.
OrthoDBiPOG091H029Q.

Family and domain databases

Gene3Di3.90.930.12. 2 hits.
HAMAPiMF_01365_B. Ribosomal_L6_B. 1 hit.
InterProiIPR000702. Ribosomal_L6.
IPR020040. Ribosomal_L6_a/b-dom.
IPR019906. Ribosomal_L6_bac-type.
IPR002358. Ribosomal_L6_CS.
[Graphical view]
PANTHERiPTHR11655. PTHR11655. 1 hit.
PfamiPF00347. Ribosomal_L6. 2 hits.
[Graphical view]
PIRSFiPIRSF002162. Ribosomal_L6. 1 hit.
PRINTSiPR00059. RIBOSOMALL6.
SUPFAMiSSF56053. SSF56053. 2 hits.
TIGRFAMsiTIGR03654. L6_bact. 1 hit.
PROSITEiPS00525. RIBOSOMAL_L6_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O32998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRIGKQPIP VPAGVDITID GQNVLVKGPK GTLDLTVAEP IMLARNDEGA
60 70 80 90 100
IVVTRPDNER RNRSLHGLSR TLVSNLVTGV TQGYTVSMEI FGVGYRAQLK
110 120 130 140 150
GSNLEFALGY SHPVVIEAPE GITFAVQSPT KFTITGIDKQ KVGQISANIR
160 170
RLRRPDPYKG KGVRYEGEQI RRKVGKTGK
Length:179
Mass (Da):19,493
Last modified:January 1, 1998 - v1
Checksum:i12BF68CA82F6471D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z98756 Genomic DNA. Translation: CAB11451.1.
AL583923 Genomic DNA. Translation: CAC30798.1.
PIRiT45381.
RefSeqiNP_302250.1. NC_002677.1.
WP_010908571.1. NC_002677.1.

Genome annotation databases

EnsemblBacteriaiCAC30798; CAC30798; CAC30798.
GeneIDi910646.
KEGGimle:ML1844.
PATRICi18057134. VBIMycLep78757_3494.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z98756 Genomic DNA. Translation: CAB11451.1.
AL583923 Genomic DNA. Translation: CAC30798.1.
PIRiT45381.
RefSeqiNP_302250.1. NC_002677.1.
WP_010908571.1. NC_002677.1.

3D structure databases

ProteinModelPortaliO32998.
SMRiO32998. Positions 8-179.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272631.ML1844.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC30798; CAC30798; CAC30798.
GeneIDi910646.
KEGGimle:ML1844.
PATRICi18057134. VBIMycLep78757_3494.

Organism-specific databases

LepromaiML1844.

Phylogenomic databases

eggNOGiENOG4108R5J. Bacteria.
COG0097. LUCA.
HOGENOMiHOG000039903.
KOiK02933.
OMAiLIANMVE.
OrthoDBiPOG091H029Q.

Family and domain databases

Gene3Di3.90.930.12. 2 hits.
HAMAPiMF_01365_B. Ribosomal_L6_B. 1 hit.
InterProiIPR000702. Ribosomal_L6.
IPR020040. Ribosomal_L6_a/b-dom.
IPR019906. Ribosomal_L6_bac-type.
IPR002358. Ribosomal_L6_CS.
[Graphical view]
PANTHERiPTHR11655. PTHR11655. 1 hit.
PfamiPF00347. Ribosomal_L6. 2 hits.
[Graphical view]
PIRSFiPIRSF002162. Ribosomal_L6. 1 hit.
PRINTSiPR00059. RIBOSOMALL6.
SUPFAMiSSF56053. SSF56053. 2 hits.
TIGRFAMsiTIGR03654. L6_bact. 1 hit.
PROSITEiPS00525. RIBOSOMAL_L6_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL6_MYCLE
AccessioniPrimary (citable) accession number: O32998
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.