O32994 (RL24_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L24

Gene names

Name:	rplX
Ordered Locus Names:	ML1848
ORF Names:	MLCB2492.15

Organism

Mycobacterium leprae [Complete proteome] [HAMAP]

Taxonomic identifier

1769 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit By similarity. HAMAP MF_01326_B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit By similarity. HAMAP MF_01326_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L24P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 105	105	50S ribosomal protein L24 HAMAP MF_01326_B		PRO_0000130679

Sequences

	Sequence		Length	Mass (Da)
	O32994 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: C1D9A628592EDE2D	FASTA	105	11,412
	10 20 30 40 50 60 MKVHKGDTVL VIAGKDKGAK GKVLQAYPAR NRVLVEGVNR IKKHTAISAN QRGAQAGGIV 70 80 90 100 TQEAPIHVSN VMVVDSDGKP TRIGYRVDEE TDKRVRISKR NGKDI

References

[1]

"Massive gene decay in the leprosy bacillus." Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E., Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., Duthoy S. , Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S., Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R., Barrell B.G. Nature 409:1007-1011(2001) [PubMed: 11234002] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TN.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z98756 Genomic DNA. Translation: CAB11447.1. AL583923 Genomic DNA. Translation: CAC30802.1.
PIR	T45377.
RefSeq	NP_302254.1. NC_002677.1.
3D structure databases
ProteinModelPortal	O32994.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000028099; EBMYCP00000027705; EBMYCG00000028094.
GeneID	910642.
GenomeReviews	Gene locus ML1848 in contig AL450380_GR.
KEGG	mle:ML1848.
NMPDR	fig|272631.1.peg.1126.
PATRIC	18057142. VBIMycLep78757_3498.
Organism-specific databases
Leproma	ML1848.
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016303.
HOGENOM	HBG588578.
OMA	KPTRVGY.
ProtClustDB	PRK00004.
Enzyme and pathway databases
BioCyc	MLEP272631:ML1848-MONOMER.
Family and domain databases
HAMAP	MF_01326_B. Ribosomal_L24_B. [Tree]
InterPro	IPR005824. KOW. IPR003256. Ribosomal_L24. IPR005825. Ribosomal_L24/26_CS. IPR014723. Ribosomal_L24_SH3-like. IPR008991. Translation_prot_SH3-like. [Graphical view]
Gene3D	G3DSA:2.30.30.200. Ribosomal_L24_SH3-like. 1 hit.
KO	K02895.
PANTHER	PTHR12903. Ribosomal_L24. 1 hit.
Pfam	PF00467. KOW. 1 hit. [Graphical view]
SMART	SM00739. KOW. 1 hit. [Graphical view]
SUPFAM	SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR01079. RplX_bact. 1 hit.
PROSITE	PS01108. RIBOSOMAL_L24. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL24_MYCLE

Accession

Primary (citable) accession number: O32994

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	January 1, 1998
Last modified:	January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program