O32979 (O32979_MYCLE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Serine acetyltransferase PIRNR PIRNR000441
EC=2.3.1.30 PIRNR PIRNR000441

Gene names

Name:	cysE EMBL CAB11413.1
Ordered Locus Names:	ML0838

Organism

Mycobacterium leprae [Complete proteome] [HAMAP] EMBL CAB11413.1

Taxonomic identifier

1769 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine. PIRNR PIRNR000441
Sequence similarities	Belongs to the transferase hexapeptide repeat family. PIRNR PIRNR000441

Ontologies

Keywords
Molecular function	Acyltransferase PIRNR PIRNR000441 EMBL CAC30348.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	serine O-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O32979 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 829CA191447C4913	FASTA	227	23,917
	10 20 30 40 50 60 MFAAIRRDIQ AARQRDPAQP TVLEVICCYP GVHAVWGHRI SHWLWNRRAR LAARAFAELT 70 80 90 100 110 120 RILTGVDIHP GAVLGAGLFI DHATGVVIGE TAEVGDDVTI FHGVTLGGTG RETGKRHPTI 130 140 150 160 170 180 GDRVTIGAGA KVLGAIKIGE DSRIGANAVV VKEVPASAVA VGVPGQIISS DSPANGDDSV 190 200 210 220 LPDFVGVSLQ SLLTRVAKLE AEDGGSQTYR VIRLPEAGVW HGEDFSI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae." Eiglmeier K., Honore N., Woods S.A., Caudron B., Cole S.T. Mol. Microbiol. 7:197-206(1993) [PubMed: 8446027] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Massive gene decay in the leprosy bacillus." Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E., Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., Duthoy S. , Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S., Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R., Barrell B.G. Nature 409:1007-1011(2001) [PubMed: 11234002] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TN.
[3]	Devlin K., Churcher C.M. Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Parkhill J., Barrell B.G., Rajandream M.A. Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z98741 Genomic DNA. Translation: CAB11413.1. AL583919 Genomic DNA. Translation: CAC30348.1.
PIR	T44913.
RefSeq	NP_301632.1. NC_002677.1.
3D structure databases
ProteinModelPortal	O32979.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000029445; EBMYCP00000029051; EBMYCG00000029440.
GeneID	909803.
GenomeReviews	Gene locus ML0838 in contig AL450380_GR.
KEGG	mle:ML0838.
NMPDR	fig|272631.1.peg.504.
PATRIC	18053216. VBIMycLep78757_1553.
Organism-specific databases
Leproma	ML0838.
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017947.
HOGENOM	HBG754554.
OMA	TIKDNCL.
ProtClustDB	CLSK791792.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR018357. Hexapep_transf_CS. IPR010493. Ser_AcTrfase_N. IPR005881. Ser_O-AcTrfase. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00640.
Pfam	PF00132. Hexapep. 1 hit. PF06426. SATase_N. 1 hit. [Graphical view]
PIRSF	PIRSF000441. CysE. 1 hit.
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR01172. CysE. 1 hit.
PROSITE	PS00101. HEXAPEP_TRANSFERASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O32979_MYCLE

Accession

Primary (citable) accession number: O32979

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)