O32881 (SSRP_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SsrA-binding protein

Gene names

Name:	smpB
Ordered Locus Names:	ML0671
ORF Names:	MLCB1779.19c

Organism

Mycobacterium leprae [Complete proteome] [HAMAP]

Taxonomic identifier

1769 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP MF_00023
Subcellular location	Cytoplasm Potential HAMAP MF_00023.
Sequence similarities	Belongs to the SmpB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	SsrA-binding protein HAMAP MF_00023		PRO_0000102984

Sequences

	Sequence		Length	Mass (Da)
	O32881 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 99914B92F4F7CFC2	FASTA	160	18,205
	10 20 30 40 50 60 MARNPRGGKQ IVATNRKARH DYAIIELFEA GVALLGTEVK SLREGHASLA DAFATVDSGE 70 80 90 100 110 120 VWLRNMHIPE YQHGSWTNHD PRRNRKLLLH RRQIDTLVGK IRDGNLALVP LSLYFAEGKV 130 140 150 160 KVELALARGK KLHDKRQDMA RRDAQREVIR ELGRRAKGML

References

[1]

"Massive gene decay in the leprosy bacillus." Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E., Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., Duthoy S. , Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S., Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R., Barrell B.G. Nature 409:1007-1011(2001) [PubMed: 11234002] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TN.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z98271 Genomic DNA. Translation: CAB11000.1. AL583919 Genomic DNA. Translation: CAC30180.1.
PIR	T45309.
RefSeq	NP_301544.1. NC_002677.1.
3D structure databases
ProteinModelPortal	O32881.
SMR	O32881. Positions 11-130.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000029366; EBMYCP00000028972; EBMYCG00000029361.
GeneID	910083.
GenomeReviews	Gene locus ML0671 in contig AL450380_GR.
KEGG	mle:ML0671.
NMPDR	fig|272631.1.peg.416.
PATRIC	18052498. VBIMycLep78757_1195.
Organism-specific databases
Leproma	ML0671.
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017126.
HOGENOM	HBG293422.
OMA	EKYEAGI.
ProtClustDB	PRK05422.
Enzyme and pathway databases
BioCyc	MLEP272631:ML0671-MONOMER.
Family and domain databases
HAMAP	MF_00023. SmpB. [Tree]
InterPro	IPR023620. SmpB. IPR000037. SsrA-bd_prot. IPR020081. SsrA-bd_prot_CS. [Graphical view]
Gene3D	G3DSA:2.40.280.10. SmpB. 1 hit.
KO	K03664.
Pfam	PF01668. SmpB. 1 hit. [Graphical view]
ProDom	PD004488. SmpB. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF74982. SmpB. 1 hit.
TIGRFAMs	TIGR00086. SmpB. 1 hit.
PROSITE	PS01317. SSRP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSRP_MYCLE

Accession

Primary (citable) accession number: O32881

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	January 1, 1998
Last modified:	January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program