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UniProtKB - O32847 (CH60_LACZE)

UniProt

O32847 - CH60_LACZE

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Protein

60 kDa chaperonin

Gene

groL

Organism
Lactobacillus zeae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
HSP60
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
OrganismiLactobacillus zeae
Taxonomic identifieri57037 [NCBI]
Taxonomic lineageiBacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus ›

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 54454460 kDa chaperoninPRO_0000063403Add
BLAST

Proteomic databases

PRIDEiO32847.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO32847.
SMRiO32847. Positions 2-523.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O32847-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEIKFSED ARAAMLRGVD QLANTVKTTL GPKGRNVVLD KSYGSPEITN 
        60         70         80         90        100
DGVTIAKSID LEDHYENMGA KLVAEVASKT NDIAGDGTTT ATVLAQSIIR 
       110        120        130        140        150
EGMKNVTAGA NPVGIRTGIE KATKAAVDEL HKISHKVNGK KEIAQVASVS 
       160        170        180        190        200
SSNTEVGSLI ADAMEKVGHD GVITIEESKG IDTELSVVEG MQFDRGYLSQ 
       210        220        230        240        250
YMVTDNDKME ADLDDPYILI TDKKISNIQD ILPLLQEIVQ QGKALLIIAD 
       260        270        280        290        300
DVAGEALPTL VLNKIRGTFN VVAVKAPGFG DRRKAQLEDI ATLTGGTVIS 
       310        320        330        340        350
SDLGLDLKDT KLEQLGRAGK VTVTKDNTTI VDGAGSKDAI AERVNIIKKQ 
       360        370        380        390        400
IDDTTSDFDR EKLQERLAKL AGGVAVVKVG AATETELKER KYRIEDALNA 
       410        420        430        440        450
TRAAVEEGYV AGGGTALVDV LPAVAALKEE GDVQTGINIV LRALEEPVRQ 
       460        470        480        490        500
IAENAGKEGS VIVEQLKKEK QGVGYNAATD EWEDMAKSGI IDPTKVTRSA 
       510        520        530        540 
LQNAASVAAL MLTTEAVVAD KPDPNANNNA AAGANPAAGM GGMM
Length:544
Mass (Da):57,428
Last modified:January 1, 1998 - v1
Checksum:iAA2F544F4AC2A1AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF010281 Genomic DNA. Translation: AAB66326.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF010281 Genomic DNA. Translation: AAB66326.1.

3D structure databases

ProteinModelPortaliO32847.
SMRiO32847. Positions 2-523.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiO32847.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCH60_LACZE
AccessioniPrimary (citable) accession number: O32847
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: January 1, 1998
Last modified: November 11, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.