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Protein

RNA polymerase sigma factor

Gene
N/A
Organism
Geobacillus stearothermophilus (Bacillus stearothermophilus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
OrganismiGeobacillus stearothermophilus (Bacillus stearothermophilus)Imported
Taxonomic identifieri1422 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
spoIIABO327275EBI-1033248,EBI-1033242

Protein-protein interaction databases

IntActiO32728. 1 interactor.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1L0OX-ray2.90C7-245[»]
DisProtiDP00902.
ProteinModelPortaliO32728.
SMRiO32728.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO32728.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 72RNA_pol_sigma70InterPro annotationAdd BLAST14
Domaini218 – 244RNA_pol_sigma70InterPro annotationAdd BLAST27

Sequence similaritiesi

Belongs to the sigma-70 factor family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiView protein in InterPro
IPR014284. RNA_pol_sigma-70_dom.
IPR014322. RNA_pol_sigma-B/F/G.
IPR014236. RNA_pol_sigma-F.
IPR000943. RNA_pol_sigma70.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR036388. WH-like_DNA-bd_sf.
PfamiView protein in Pfam
PF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
PIRSFiPIRSF000770. RNA_pol_sigma-SigE/K. 1 hit.
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02980. SigBFG. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
TIGR02885. spore_sigF. 1 hit.
PROSITEiView protein in PROSITE
PS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O32728-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVDVKQGQS PIKDQEMKEL IRRSQEGDQE ARDEIIEKNM RLVWSVVQRF
60 70 80 90 100
LNRGYEADDL FQIGCIGLLK SVDKFDLSYD VKFSTYAVPM IIGEIQRFLR
110 120 130 140 150
DDGTVKVSRS LKEMGNKIRK AKDELSKTRG RSPTITEIAD HLGISPEDVV
160 170 180 190 200
LAQEAVRLPT SIHETVYEND GDPITLLDQI ADADEASWFD KIALKKAIEE
210 220 230 240 250
LDERERLIVY LRYYRDRTQS EVASRLGISQ VQVSRLEKKI LQHIKDKMDG
Length:250
Mass (Da):28,775
Last modified:January 1, 1998 - v1
Checksum:iD0B9CBC7DDE41465
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L47360 Genomic DNA. Translation: AAB81194.1.

Similar proteinsi

Entry informationi

Entry nameiO32728_GEOSE
AccessioniPrimary (citable) accession number: O32728
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: October 25, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources