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O32728

- O32728_GEOSE

UniProt

O32728 - O32728_GEOSE

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Protein
RNA polymerase sigma factor
Gene
N/A
Organism
Geobacillus stearothermophilus (Bacillus stearothermophilus)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released By similarity.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. protein binding Source: IntAct
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
  4. sigma factor activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Sigma factorUniRule annotationSAAS annotations

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
OrganismiGeobacillus stearothermophilus (Bacillus stearothermophilus)Imported
Taxonomic identifieri1422 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
spoIIABO327275EBI-1033248,EBI-1033242

Protein-protein interaction databases

IntActiO32728. 1 interaction.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1L0OX-ray2.90C7-245[»]
ProteinModelPortaliO32728.
SMRiO32728. Positions 102-158.

Miscellaneous databases

EvolutionaryTraceiO32728.

Family & Domainsi

Sequence similaritiesi

Belongs to the sigma-70 factor family.UniRule annotation

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR014322. RNA_pol_sigma-B/F/G.
IPR014236. RNA_pol_sigma-F.
IPR000943. RNA_pol_sigma70.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
[Graphical view]
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02980. SigBFG. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
TIGR02885. spore_sigF. 1 hit.
PROSITEiPS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O32728-1 [UniParc]FASTAAdd to Basket

« Hide

MDVDVKQGQS PIKDQEMKEL IRRSQEGDQE ARDEIIEKNM RLVWSVVQRF    50
LNRGYEADDL FQIGCIGLLK SVDKFDLSYD VKFSTYAVPM IIGEIQRFLR 100
DDGTVKVSRS LKEMGNKIRK AKDELSKTRG RSPTITEIAD HLGISPEDVV 150
LAQEAVRLPT SIHETVYEND GDPITLLDQI ADADEASWFD KIALKKAIEE 200
LDERERLIVY LRYYRDRTQS EVASRLGISQ VQVSRLEKKI LQHIKDKMDG 250
Length:250
Mass (Da):28,775
Last modified:January 1, 1998 - v1
Checksum:iD0B9CBC7DDE41465
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L47360 Genomic DNA. Translation: AAB81194.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L47360 Genomic DNA. Translation: AAB81194.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1L0O X-ray 2.90 C 7-245 [» ]
ProteinModelPortali O32728.
SMRi O32728. Positions 102-158.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O32728. 1 interaction.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei O32728.

Family and domain databases

Gene3Di 1.10.10.10. 2 hits.
InterProi IPR014284. RNA_pol_sigma-70_dom.
IPR014322. RNA_pol_sigma-B/F/G.
IPR014236. RNA_pol_sigma-F.
IPR000943. RNA_pol_sigma70.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
[Graphical view ]
PRINTSi PR00046. SIGMA70FCT.
SUPFAMi SSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsi TIGR02980. SigBFG. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
TIGR02885. spore_sigF. 1 hit.
PROSITEi PS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequencing and phylogenetic analysis of the spoIIA operon from diverse Bacillus and Paenibacillus species."
    Park S.G., Yudkin M.D.
    Gene 194:25-33(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF."
    Campbell E.A., Masuda S., Sun J.L., Muzzin O., Olson C.A., Wang S., Darst S.A.
    Cell 108:795-807(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 7-245.

Entry informationi

Entry nameiO32728_GEOSE
AccessioniPrimary (citable) accession number: O32728
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: June 11, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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