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Protein

Anti-sigma F factor antagonist

Gene

spoIIAA

Organism
Lysinibacillus sphaericus (Bacillus sphaericus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.By similarity

GO - Biological processi

Keywordsi

Biological processSporulation

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factor antagonist
Alternative name(s):
Stage II sporulation protein AA
Gene namesi
Name:spoIIAA
OrganismiLysinibacillus sphaericus (Bacillus sphaericus)
Taxonomic identifieri1421 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeLysinibacillus

Pathology & Biotechi

Chemistry databases

DrugBankiDB04522. Phosphonoserine.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001942021 – 117Anti-sigma F factor antagonistAdd BLAST117

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei58Phosphoserine1 Publication1

Post-translational modificationi

Phosphorylated by SpoIIAB on a serine residue.By similarity

Keywords - PTMi

Phosphoprotein

PTM databases

iPTMnetiO32723.

Interactioni

Protein-protein interaction databases

STRINGi444177.Bsph_1712.

Structurei

Secondary structure

1117
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 9Combined sources7
Beta strandi12 – 21Combined sources10
Helixi23 – 38Combined sources16
Beta strandi43 – 55Combined sources13
Helixi58 – 71Combined sources14
Turni72 – 74Combined sources3
Beta strandi76 – 81Combined sources6
Helixi84 – 92Combined sources9
Helixi96 – 98Combined sources3
Helixi104 – 110Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1H4XX-ray1.16A/B1-117[»]
1H4YX-ray1.61A/B1-117[»]
1H4ZX-ray2.74A1-117[»]
ProteinModelPortaliO32723.
SMRiO32723.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO32723.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 115STASPROSITE-ProRule annotationAdd BLAST114

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG41082AN. Bacteria.
COG1366. LUCA.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiView protein in InterPro
IPR003658. Anti-sigma_ant.
IPR014237. Anti-sigma_F_ant.
IPR002645. STAS_dom.
PfamiView protein in Pfam
PF01740. STAS. 1 hit.
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
TIGR02886. spore_II_AA. 1 hit.
PROSITEiView protein in PROSITE
PS50801. STAS. 1 hit.

Sequencei

Sequence statusi: Complete.

O32723-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHFQLEMVTR ETVVIRLFGE LDHHAVEQIR AKISAAIFQG TVTTIIWNLE
60 70 80 90 100
GLSFMDSSGV GLVLGRMREL EAVAGRTILL NPSPTMRKVF QFSGLGPWMM
110
DATEEQAIDR VRGIVNG
Length:117
Mass (Da):13,043
Last modified:January 1, 1998 - v1
Checksum:iC3BF8A70AB9340A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L47359 Genomic DNA. Translation: AAB81189.1.
RefSeqiWP_025114066.1. NZ_LWHI01000001.1.

Genome annotation databases

GeneIDi29441082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L47359 Genomic DNA. Translation: AAB81189.1.
RefSeqiWP_025114066.1. NZ_LWHI01000001.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1H4XX-ray1.16A/B1-117[»]
1H4YX-ray1.61A/B1-117[»]
1H4ZX-ray2.74A1-117[»]
ProteinModelPortaliO32723.
SMRiO32723.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi444177.Bsph_1712.

Chemistry databases

DrugBankiDB04522. Phosphonoserine.

PTM databases

iPTMnetiO32723.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi29441082.

Phylogenomic databases

eggNOGiENOG41082AN. Bacteria.
COG1366. LUCA.

Miscellaneous databases

EvolutionaryTraceiO32723.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiView protein in InterPro
IPR003658. Anti-sigma_ant.
IPR014237. Anti-sigma_F_ant.
IPR002645. STAS_dom.
PfamiView protein in Pfam
PF01740. STAS. 1 hit.
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
TIGR02886. spore_II_AA. 1 hit.
PROSITEiView protein in PROSITE
PS50801. STAS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSP2AA_LYSSH
AccessioniPrimary (citable) accession number: O32723
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: March 15, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.