Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

RNA polymerase sigma factor RpoD

Gene

rpoD

Organism
Helicobacter pylori (Campylobacter pylori)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.SAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi645 – 664H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor RpoDUniRule annotation
Alternative name(s):
Sigma-70UniRule annotation
Gene namesi
Name:rpoDUniRule annotationImported
OrganismiHelicobacter pylori (Campylobacter pylori)Imported
Taxonomic identifieri210 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Interacts transiently with the RNA polymerase catalytic core.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO32637
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini474 – 487RNA_pol_sigma70InterPro annotationAdd BLAST14
Domaini644 – 670RNA_pol_sigma70InterPro annotationAdd BLAST27

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni450 – 520Sigma-70 factor domain-2UniRule annotationAdd BLAST71
Regioni529 – 605Sigma-70 factor domain-3UniRule annotationAdd BLAST77

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili22 – 64Sequence analysisAdd BLAST43
Coiled coili608 – 628Sequence analysisAdd BLAST21

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi474 – 477Interaction with polymerase core subunit RpoCUniRule annotation4

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105DG1 Bacteria
COG0568 LUCA

Family and domain databases

Gene3Di1.10.10.10, 2 hits
HAMAPiMF_00963 Sigma70_RpoD_SigA, 1 hit
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR009042 RNA_pol_sigma70_r1_2
IPR007627 RNA_pol_sigma70_r2
IPR007624 RNA_pol_sigma70_r3
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR012760 RNA_pol_sigma_RpoD_C
IPR028630 Sigma70_RpoD
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00140 Sigma70_r1_2, 1 hit
PF04542 Sigma70_r2, 1 hit
PF04539 Sigma70_r3, 1 hit
PF04545 Sigma70_r4, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 2 hits
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02393 RpoD_Cterm, 1 hit
TIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit
PS00716 SIGMA70_2, 1 hit

Sequencei

Sequence statusi: Complete.

O32637-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSYFMESPM KKKANEEKAP KRAKQEAKTE VAQENKAKEN NKTKESKIKE
60 70 80 90 100
NKTKESKIKE AKAKEPVPVK KLSFNEALEE LFANSLSDCV SYESIIQISA
110 120 130 140 150
KVPTLAQVKK IKELCQKYQK KLVSSSEYAK KLNAIDKIKK TEEKQKVLDE
160 170 180 190 200
ELEDGYDFLK EKDFLEWSRS DSPVRMYLRE MGDIKLLSKD EEIELSKQIR
210 220 230 240 250
LGEDIILDAI CSVPYLIDFI YAYKDALINR ERRVKELFRS FDDDDENSVS
260 270 280 290 300
DSKKDDDNEE DEENEERKKV VSEKDRKRVE KVQESFKALD KAKKEWLKAL
310 320 330 340 350
EAPVDEKEDE LVRLLTLAYK RQTLKDRLYD LEPTSKLINE LVKTMETTLK
360 370 380 390 400
SGDGFEKELK RLEYKLPLFN DTLIANHKKI LANITNMTKE DIIAQVPEAT
410 420 430 440 450
MVSVYMDLKK LFLTKEASEE GFDLAPNKLK EILEQIKRGK LISDRAKNKM
460 470 480 490 500
AKSNLRLVVS IAKRFTSRGL PFLDLIQEGN IGLMKAVDKF EHEKGFKFST
510 520 530 540 550
YATWWIKQAI SRAIADQART IRIPIHMIDT INRINKVMRK HIQETGKEPD
560 570 580 590 600
LEVVAEEVGL SLDKVKNVIK VTKEPISLET PVGNDDDGKF GDFVEDKNIV
610 620 630 640 650
SSIDHIMRED LKAQIESVLD QLNEREKAVI RMRFGLLDDE SDRTLEEIGK
660 670 680
ELNVTRERVR QIESSAIKKL RSPQYGRILR NYLRI
Length:685
Mass (Da):79,349
Last modified:January 1, 1998 - v1
Checksum:i3634E4DD410AE18C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF009177 Genomic DNA Translation: AAC64856.1

Similar proteinsi

Entry informationi

Entry nameiO32637_HELPX
AccessioniPrimary (citable) accession number: O32637
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health