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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei164By similarity1
Active sitei598By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Enzyme and pathway databases

BioCyciRPAL258594:G1GT2-1818-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppc
Ordered Locus Names:RPA1772
OrganismiRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Taxonomic identifieri258594 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001426 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001666181 – 936Phosphoenolpyruvate carboxylaseAdd BLAST936

Proteomic databases

PRIDEiO32483

Interactioni

Protein-protein interaction databases

STRINGi258594.RPA1772

Structurei

3D structure databases

ProteinModelPortaliO32483
SMRiO32483
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.Curated

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O
PhylomeDBiO32483

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

O32483-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLNLSAGP EPVSERPDDA AAIEAETRLR NDIRLLGRIL GDTVREQEGQ
60 70 80 90 100
SVFDLVENIR QTSIRFHRDD DKTARAELAA ILDGMSIQDT MRIVRAFSYF
110 120 130 140 150
SHLANIAEDQ NNIRQMRAGS TAGSAPRAGL LAKTLAHARQ EGISAAELRK
160 170 180 190 200
FFATALVSPV LTAHPTEVRR KSTMDREMQI AGLLDQRDRV QLTADEWTDN
210 220 230 240 250
EERLRRAVET LWKTNLLRRT KLTVLDEVTN GLSFYDYTFL REVPRLHSAL
260 270 280 290 300
EDRLADAAKA EGANAEGELA SFLRMGSWIG GDRDGNPFVT AEVLHGTLKL
310 320 330 340 350
QSTRVLRYYL EELHELGSEL SLASHLAGTT DTVKALAETS PDTSPHRKYE
360 370 380 390 400
PYRLAVSGIY ARLAATALKL EVENLRAPVG EAEPYASAQD FKADLDAIHL
410 420 430 440 450
SLTTHHSGVI ARGRLRQLRR AIDCFGFHLA SLDMRQNSAV HERTIGELMD
460 470 480 490 500
AARPGTSYAV LDEDARIALL ISELRSTRPL TSMFVKYSDE TVGELAVFRE
510 520 530 540 550
AAKAHATYGA AAIPQCIISM TKGVSDLLEL AVLLKEVGLI DPSGRSAINV
560 570 580 590 600
VPLFETIEDL QACAKIMDRL LSIPEYRRLV DSRGSVQEVM LGYSDSNKDG
610 620 630 640 650
GFVTSGWELY KAEIGLIEIF EHHGVRLRLF HGRGGSVGRG GGPSYDAIVA
660 670 680 690 700
QPGGAVNGQI RITEQGEIIT SKYSNVEVGR NNLEILAAAT LEASLLQPKR
710 720 730 740 750
VAPHRDYLEA MEQLSALAFK AYRGLVYETD GFVDYFWAST VINEISTLNI
760 770 780 790 800
GSRPASRKKT RAIEDLRAIP WVFSWAQCRL MLPGWYGFGS AVSAWVTEHP
810 820 830 840 850
EKGIAFLQAM YQEWPFFRTL LSNMDMVLSK SSIGIASRYA ELVEDTAIRD
860 870 880 890 900
RIFSRIRAEW HSSIDYLLAI MQQDHLLQSN PLLERSIRHR FPYLDPLNHV
910 920 930
QVQLLREHRT HDPDEQVLRG VQLTINGISA GLRNSG
Length:936
Mass (Da):104,139
Last modified:February 16, 2004 - v2
Checksum:iF95CF9565356EA4F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti51S → T in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti79A → E in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti88Q → P in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti182G → S in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti198T → A in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti263 – 266ANAE → VNSD in BAA21835 (PubMed:9244286).Curated4
Sequence conflicti311E → D in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti404 – 406THH → QHN in BAA21835 (PubMed:9244286).Curated3
Sequence conflicti446G → T in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti460V → M in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti464D → E in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti530L → V in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti671S → R in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti798E → A in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti802K → T in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti809A → K in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti846 – 850TAIRD → VDVRE in BAA21835 (PubMed:9244286).Curated5
Sequence conflicti854S → G in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti865D → E in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti868L → F in BAA21835 (PubMed:9244286).Curated1
Sequence conflicti875H → R in BAA21835 (PubMed:9244286).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89668 Genomic DNA Translation: BAA21835.1
BX572598 Genomic DNA Translation: CAE27213.1
RefSeqiWP_011157278.1, NC_005296.1

Genome annotation databases

EnsemblBacteriaiCAE27213; CAE27213; RPA1772
KEGGirpa:RPA1772

Similar proteinsi

Entry informationi

Entry nameiCAPP_RHOPA
AccessioniPrimary (citable) accession number: O32483
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 16, 2004
Last modified: May 23, 2018
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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