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O32450

- MALQ_THEKO

UniProt

O32450 - MALQ_THEKO

Protein

4-alpha-glucanotransferase

Gene

TK1809

Organism
Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei123 – 1231NucleophileBy similarity
    Active sitei214 – 2141Proton donorBy similarity

    GO - Molecular functioni

    1. 4-alpha-glucanotransferase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism

    Enzyme and pathway databases

    BioCyciTKOD69014:GH72-1846-MONOMER.

    Protein family/group databases

    CAZyiGH57. Glycoside Hydrolase Family 57.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    4-alpha-glucanotransferase (EC:2.4.1.25)
    Alternative name(s):
    Amylomaltase
    Disproportionating enzyme
    Short name:
    D-enzyme
    Gene namesi
    Ordered Locus Names:TK1809
    OrganismiThermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
    Taxonomic identifieri69014 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
    ProteomesiUP000000536: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 6536534-alpha-glucanotransferasePRO_0000184576Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi69014.TK1809.

    Structurei

    3D structure databases

    ProteinModelPortaliO32450.
    SMRiO32450. Positions 2-653.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 57 family.Curated

    Phylogenomic databases

    eggNOGiCOG1449.
    HOGENOMiHOG000223207.
    KOiK01176.

    Family and domain databases

    Gene3Di2.70.98.10. 1 hit.
    3.20.110.10. 2 hits.
    InterProiIPR015179. A-amylase/a-glucTrfase_C.
    IPR015178. A-amylase/a-glucTrfase_central.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR011330. Glyco_hydro/deAcase_b/a-brl.
    IPR027291. Glyco_hydro_38/57_N.
    IPR028995. Glyco_hydro_57/38_cen.
    IPR004300. Glyco_hydro_57_N.
    [Graphical view]
    PfamiPF09094. DUF1925. 1 hit.
    PF09095. DUF1926. 1 hit.
    PF03065. Glyco_hydro_57. 1 hit.
    [Graphical view]
    ProDomiPD014405. DUF1925. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF74650. SSF74650. 1 hit.
    SSF88688. SSF88688. 1 hit.
    SSF88713. SSF88713. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O32450-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEMVNFIFGI HNHQPLGNFG WVMESAYERS YRPFMETLEE YPNMKVAVHY    50
    SGPLLEWIRD NKPEHLDLLR SLVKRGQLEI VVAGFYEPVL ASIPKEDRIV 100
    QIEKLKEFAR NLGYEARGVW LTERVWQPEL VKSLRAAGID YVIVDDYHFM 150
    SAGLSKDELF WPYYTEDGGE VITVFPIDEK LRYLIPFRPV DKTLEYLHSL 200
    DDGDESKVAV FHDDGEKFGV WPGTYEWVYE KGWLREFFDR VSSDERINLM 250
    LYSEYLQRFR PRGLVYLPIA SYFEMSEWSL PARQAKLFVE FVEELKKENK 300
    FDRYRVFVRG GIWKNFFFKY PESNYMHKRM LMVSKAVRNN PEAREFILRA 350
    QCNDAYWHGV FGGVYLPHLR RAVWENIIKA QSHVKTGNFV RDIDFDGRDE 400
    VFIENENFYA VFKPAYGGAL FELSSKRKAV NYNDVLARRW EHYHEVPEAA 450
    TPEEGGEGVA SIHELGKQIP DEIRRELAYD SHLRAILQDH FLEPETTLDE 500
    YRLSRYIELG DFLTGAYNFS LIENGITLER DGSVAKRPAR VEKSVRLTED 550
    GFIVDYTVRS DARALFGVEL NLAVHSVMEE PAEFEAEKFE VNDPYGIGKV 600
    EIELDRRAKV WKYPIKTLSQ SESGWDFIQQ GVSYTVLFPV EGELRFRLRF 650
    REL 653
    Length:653
    Mass (Da):76,665
    Last modified:January 1, 1998 - v1
    Checksum:iB0C4695613F29219
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D87907 Genomic DNA. Translation: BAA22062.1.
    AP006878 Genomic DNA. Translation: BAD85998.1.
    RefSeqiYP_184222.1. NC_006624.1.

    Genome annotation databases

    EnsemblBacteriaiBAD85998; BAD85998; TK1809.
    GeneIDi3235018.
    KEGGitko:TK1809.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D87907 Genomic DNA. Translation: BAA22062.1 .
    AP006878 Genomic DNA. Translation: BAD85998.1 .
    RefSeqi YP_184222.1. NC_006624.1.

    3D structure databases

    ProteinModelPortali O32450.
    SMRi O32450. Positions 2-653.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 69014.TK1809.

    Protein family/group databases

    CAZyi GH57. Glycoside Hydrolase Family 57.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD85998 ; BAD85998 ; TK1809 .
    GeneIDi 3235018.
    KEGGi tko:TK1809.

    Phylogenomic databases

    eggNOGi COG1449.
    HOGENOMi HOG000223207.
    KOi K01176.

    Enzyme and pathway databases

    BioCyci TKOD69014:GH72-1846-MONOMER.

    Family and domain databases

    Gene3Di 2.70.98.10. 1 hit.
    3.20.110.10. 2 hits.
    InterProi IPR015179. A-amylase/a-glucTrfase_C.
    IPR015178. A-amylase/a-glucTrfase_central.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    IPR011330. Glyco_hydro/deAcase_b/a-brl.
    IPR027291. Glyco_hydro_38/57_N.
    IPR028995. Glyco_hydro_57/38_cen.
    IPR004300. Glyco_hydro_57_N.
    [Graphical view ]
    Pfami PF09094. DUF1925. 1 hit.
    PF09095. DUF1926. 1 hit.
    PF03065. Glyco_hydro_57. 1 hit.
    [Graphical view ]
    ProDomi PD014405. DUF1925. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF74650. SSF74650. 1 hit.
    SSF88688. SSF88688. 1 hit.
    SSF88713. SSF88713. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and expression of the 4-alpha-glucanotransferase gene from the hyperthermophilic archaeon Pyrococcus sp. KOD1, and characterization of the enzyme."
      Tachibana Y., Fujiwara S., Takagi M., Imanaka T.
      J. Ferment. Bioeng. 83:540-548(1997)
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC BAA-918 / JCM 12380 / KOD1.
    2. "Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
      Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
      Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-918 / JCM 12380 / KOD1.

    Entry informationi

    Entry nameiMALQ_THEKO
    AccessioniPrimary (citable) accession number: O32450
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 29, 2001
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3