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Protein

Beta-xylanase

Gene

xynC

Organism
Clostridium thermocellum (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.UniRule annotation

GO - Molecular functioni

  • endo-1,4-beta-xylanase activity Source: UniProtKB-EC
  • xylan endo-1,3-beta-xylosidase activity Source: MENGO

GO - Biological processi

  • xylan catabolic process Source: MENGO
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradationImported

Enzyme and pathway databases

BRENDAi3.2.1.8. 1530.

Protein family/group databases

CAZyiCBM22. Carbohydrate-Binding Module Family 22.
GH10. Glycoside Hydrolase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-xylanaseUniRule annotation (EC:3.2.1.8UniRule annotation)
Gene namesi
Name:xynCImported
OrganismiClostridium thermocellum (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri1515 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_500415798533 – 619Beta-xylanaseSequence analysisAdd BLAST587

Interactioni

Protein-protein interaction databases

IntActiO32374. 1 interactor.
STRINGi203119.Cthe_1838.

Structurei

3D structure databases

ProteinModelPortaliO32374.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini193 – 544GH10 (glycosyl hydrolase family 10)InterPro annotationAdd BLAST352
Domaini554 – 619DockerinInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the glycosyl hydrolase 10 (cellulase F) family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105D9F. Bacteria.
COG3693. LUCA.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR003305. CenC_carb-bd.
IPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR008979. Galactose-bd-like.
IPR001000. GH10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02018. CBM_4_9. 1 hit.
PF00404. Dockerin_1. 2 hits.
PF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF63446. SSF63446. 1 hit.
PROSITEiPS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
PS00018. EF_HAND_1. 2 hits.
PS51760. GH10_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O32374-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKKLLTLL TVFALLTVGI CGSFLPLPKA SAAALIYDDF ETGLNGWGPR
60 70 80 90 100
GPETVELTTE EAYSGRYSLK VSGRTSTWNG PMVDKTDVLT LGESYKLGVY
110 120 130 140 150
VKFVGDSYSN EQRFSLQLQY NDGAGDVYQN IKTATVYKGT WTLLEGQLTV
160 170 180 190 200
PSHAKDVKIY VETEFKNSPS PQDLMDFYID DFTATPANLP EIEKDIPSLK
210 220 230 240 250
DVFAGYFKVG GAATVAELAP KPAKELFLKH YNSLTFGNEL KPESVLDYDA
260 270 280 290 300
TIAYMEANGG DQVNPQITLR AARPLLEFAK EHNIPVRGHT LVWHSQTPDW
310 320 330 340 350
FFRENYSQDE NAPWASKEVM LQRLENYIKN LMEALATEYP TVKFYAWDVV
360 370 380 390 400
NEAVDPNTSD GMRTPGSNNK NPGSSLWMQT VGRDFIVKAF EYARKYAPAD
410 420 430 440 450
CKLFYNDYNE YEDRKCDFII EILTELKAKG LVDGMGMQSH WVMDYPSISM
460 470 480 490 500
FEKSIRRYAA LGLEIQLTEL DIRNPDNSQW ALERQANRYK ELVTKLVDLK
510 520 530 540 550
KEGINITALV FWGITDATSW LGGYPLLFDA EYKAKPAFYA IVNSVPPLPT
560 570 580 590 600
EPPVQVIPGD VNGDGRVNSS DLTLMKRYLL KSISDFPTPE GKIAADLNED
610
GKVNSTDLLA LKKLVLREL
Length:619
Mass (Da):69,518
Last modified:November 1, 1999 - v2
Checksum:i3AC2AE8566BB039C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D84188 Genomic DNA. Translation: BAA21516.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D84188 Genomic DNA. Translation: BAA21516.2.

3D structure databases

ProteinModelPortaliO32374.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO32374. 1 interactor.
STRINGi203119.Cthe_1838.

Protein family/group databases

CAZyiCBM22. Carbohydrate-Binding Module Family 22.
GH10. Glycoside Hydrolase Family 10.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105D9F. Bacteria.
COG3693. LUCA.

Enzyme and pathway databases

BRENDAi3.2.1.8. 1530.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR003305. CenC_carb-bd.
IPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR008979. Galactose-bd-like.
IPR001000. GH10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02018. CBM_4_9. 1 hit.
PF00404. Dockerin_1. 2 hits.
PF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF63446. SSF63446. 1 hit.
PROSITEiPS00448. CLOS_CELLULOSOME_RPT. 2 hits.
PS51766. DOCKERIN. 1 hit.
PS00018. EF_HAND_1. 2 hits.
PS51760. GH10_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO32374_CLOTM
AccessioniPrimary (citable) accession number: O32374
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: November 1, 1999
Last modified: April 13, 2016
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.