O32253 (CGGR_BACSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Central glycolytic genes regulator

Gene names

Name:	cggR
Synonyms:	yvbQ
Ordered Locus Names:	BSU33950

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Represses the transcription of the gapA gene.
Sequence similarities	Belongs to the sorC transcriptional regulatory family.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Molecular function	Repressor
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 340

340

Central glycolytic genes regulator

PRO_0000062787

Regions

DNA binding

37 – 56

20

H-T-H motif Potential

Secondary structure

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340

Helix Strand Turn

Details...

Helix

94 – 104

11

Beta strand

108 – 115

8

Turn

117 – 119

3

Helix

122 – 138

17

Beta strand

141 – 147

7

Helix

151 – 159

9

Beta strand

168 – 177

10

Helix

185 – 197

13

Helix

212 – 219

8

Helix

222 – 232

11

Beta strand

235 – 239

5

Helix

244 – 250

7

Helix

255 – 263

9

Beta strand

266 – 270

5

Beta strand

273 – 276

4

Beta strand

281 – 284

4

Beta strand

286 – 289

4

Helix

292 – 297

6

Beta strand

299 – 304

6

Helix

308 – 310

3

Helix

311 – 317

7

Beta strand

324 – 329

6

Helix

330 – 337

8

Sequences

	Sequence		Length	Mass (Da)
	O32253 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 18C885966DDB42DB	FASTA	340	37,382
	10 20 30 40 50 60 MNQLIQAQKK LLPDLLLVMQ KRFEILQYIR LTEPIGRRSL SASLGISERV LRGEVQFLKE 70 80 90 100 110 120 QNLVDIKTNG MTLTEEGYEL LSVLEDTMKD VLGLTLLEKT LKERLNLKDA IIVSGDSDQS 130 140 150 160 170 180 PWVKKEMGRA AVACMKKRFS GKNIVAVTGG TTIEAVAEMM TPDSKNRELL FVPARGGLGE 190 200 210 220 230 240 DVKNQANTIC AHMAEKASGT YRLLFVPGQL SQGAYSSIIE EPSVKEVLNT IKSASMLVHG 250 260 270 280 290 300 IGEAKTMAQR RNTPLEDLKK IDDNDAVTEA FGYYFNADGE VVHKVHSVGM QLDDIDAIPD 310 320 330 340 IIAVAGGSSK AEAIEAYFKK PRNTVLVTDE GAAKKLLRDE

References

[1]

"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.

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Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AL009126 Genomic DNA. Translation: CAB15400.1.

PIR

C70030.

RefSeq

NP_391275.1. NC_000964.3.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2OKG	X-ray	1.65	A/B	89-340	[»]
3BXE	X-ray	1.80	A/B	89-340	[»]
3BXF	X-ray	1.70	A/B	89-340	[»]
3BXG	X-ray	1.80	A/B	89-340	[»]
3BXH	X-ray	1.85	A/B	89-340	[»]

ProteinModelPortal

O32253.

SMR

O32253. Positions 21-338.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBBACT00000000568; EBBACP00000000568; EBBACG00000000566.

GeneID

938570.

GenomeReviews

Gene locus BSU33950 in contig AL009126_GR.

KEGG

bsu:BSU33950.

NMPDR

fig|224308.1.peg.3401.

PATRIC

18978790. VBIBacSub10457_3558.

Organism-specific databases

GenoList

BSU33950. [Micado]

Phylogenomic databases

GeneTree

EBGT00050000002398.

HOGENOM

HBG305079.

OMA

NQPIGRR.

PhylomeDB

O32253.

ProtClustDB

CLSK873644.

Enzyme and pathway databases

BioCyc

BSUB:BSU33950-MONOMER.

Family and domain databases

InterPro

IPR007324. Sugar-bd_dom_put.
IPR011991. WHTH_trsnscrt_rep_DNA-bd.
[Graphical view]

Gene3D

G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.

KO

K05311.

Pfam

PF04198. Sugar-bind. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

CGGR_BACSU

Accession

Primary (citable) accession number: O32253

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	January 25, 2012
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program