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Protein

Transcriptional repressor SdpR

Gene

sdpR

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Represses the transcription of the sdpIR operon and of several other operons that probably contribute to delaying commitment to sporulation.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi39 – 62H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciBSUB:BSU33790-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor SdpR
Gene namesi
Name:sdpR
Synonyms:yvbA
Ordered Locus Names:BSU33790
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003127451 – 90Transcriptional repressor SdpRAdd BLAST90

Proteomic databases

PaxDbiO32242.
PRIDEiO32242.

Expressioni

Inductioni

By Spo0A during nutrient starvation through its direct negative control of AbrB, repressed by AbrB during regular growth when nutrients are plentiful (PubMed:16469701). Represses its own transcription (PubMed:16469701). Induced by expression of SDP (active peptide of sdpC) (PubMed:16469701, PubMed:23687264).1 Publication

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100018331.

Structurei

3D structure databases

ProteinModelPortaliO32242.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 87HTH arsR-typePROSITE-ProRule annotationAdd BLAST87

Sequence similaritiesi

Contains 1 HTH arsR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG41082BM. Bacteria.
COG0640. LUCA.
HOGENOMiHOG000144508.
InParanoidiO32242.
OMAiHIYYSLN.
PhylomeDBiO32242.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01022. HTH_5. 1 hit.
[Graphical view]
PRINTSiPR00778. HTHARSR.
SMARTiSM00418. HTH_ARSR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50987. HTH_ARSR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O32242-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNVFKAISD PTRRKILDLL KGGDMTAGDI AEHFNISKPS ISHHLNILKQ
60 70 80 90
AEVISDHRKG QFIYYSLNTT VLQDSINWML NFINKGDNDL
Length:90
Mass (Da):10,243
Last modified:January 1, 1998 - v1
Checksum:iE2008BDD17975113
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB15384.1.
PIRiD70029.
RefSeqiNP_391259.1. NC_000964.3.
WP_003243541.1. NZ_JNCM01000033.1.

Genome annotation databases

EnsemblBacteriaiCAB15384; CAB15384; BSU33790.
GeneIDi936249.
KEGGibsu:BSU33790.
PATRICi18978758. VBIBacSub10457_3542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB15384.1.
PIRiD70029.
RefSeqiNP_391259.1. NC_000964.3.
WP_003243541.1. NZ_JNCM01000033.1.

3D structure databases

ProteinModelPortaliO32242.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100018331.

Proteomic databases

PaxDbiO32242.
PRIDEiO32242.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15384; CAB15384; BSU33790.
GeneIDi936249.
KEGGibsu:BSU33790.
PATRICi18978758. VBIBacSub10457_3542.

Phylogenomic databases

eggNOGiENOG41082BM. Bacteria.
COG0640. LUCA.
HOGENOMiHOG000144508.
InParanoidiO32242.
OMAiHIYYSLN.
PhylomeDBiO32242.

Enzyme and pathway databases

BioCyciBSUB:BSU33790-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01022. HTH_5. 1 hit.
[Graphical view]
PRINTSiPR00778. HTHARSR.
SMARTiSM00418. HTH_ARSR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50987. HTH_ARSR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSDPR_BACSU
AccessioniPrimary (citable) accession number: O32242
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: January 1, 1998
Last modified: October 5, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.