SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O32138

- PUCR_BACSU

UniProt

O32138 - PUCR_BACSU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Purine catabolism regulatory protein

Gene
pucR, yunI, BSU32420
Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Activates the expression of pucFG, pucH, pucI, pucJKLM and guaD, while it represses pucABCDE and its own expression.2 Publications

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. purine nucleobase metabolic process Source: UniProtKB-KW
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Repressor

Keywords - Biological processi

Purine metabolism, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciBSUB:BSU32420-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purine catabolism regulatory protein
Gene namesi
Name:pucR
Synonyms:yunI
Ordered Locus Names:BSU32420
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570: Chromosome

Organism-specific databases

GenoListiBSU32420. [Micado]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 531531Purine catabolism regulatory proteinPRO_0000165945Add
BLAST

Proteomic databases

PaxDbiO32138.

Expressioni

Inductioni

Expression is very low in excess nitrogen (glutamate plus ammonia) and is induced during limiting-nitrogen conditions (glutamate). Expression slightly decreases when allantoin is added during limiting-nitrogen conditions.

Interactioni

Protein-protein interaction databases

STRINGi224308.BSU32420.

Structurei

3D structure databases

ProteinModelPortaliO32138.
SMRiO32138. Positions 470-503.

Family & Domainsi

Sequence similaritiesi

Belongs to the CdaR family.

Phylogenomic databases

eggNOGiCOG2508.
HOGENOMiHOG000009087.
KOiK09684.
OMAiRNEPVYI.
OrthoDBiEOG6038SW.
PhylomeDBiO32138.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR025736. PucR_C-HTH_dom.
IPR012914. PucR_dom.
[Graphical view]
PfamiPF13556. HTH_30. 1 hit.
PF07905. PucR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O32138-1 [UniParc]FASTAAdd to Basket

« Hide

MNILDVMKIP AFENANLIAG KAGGEREVQH VNMMDAPDIV DFLHKNELLV    50
TTAYHLKDHP HQLSELIRQM AKRGCAGLGI KTKRYLEDIP KEIIELADSY 100
AFPIIELPEH IRLGDIVNAT LSHILDMRSN ELQQAIYAHK KFTNHIMSGK 150
GLQSLLKKVS DILQLPVLLL DQHAKMLSAS HQISVETEKL KGTLNTVSGP 200
FFTCFSTISD QKTYSVLPIY NHEKNCGYLL IPDMVQAGDK GLILTIEQAA 250
NVISFELLKE NALKQFSRRA RNEFFNNFIE RTFSSDDEIK NRAKEFKLRW 300
DQKYMCIAGK LDRNDESISF TENQLASDSV FEFLEGELSA FPFPPHFFMK 350
GNVGIILIEA TDSWSEMHAS VISFLEQFQT QVSAQFKRTV SFGISNICQK 400
LIDVPDAFTE ASDALQSGHL SRSTAFIQVY HAKDVPELLR LLPVEDLKKF 450
YNSTLQSLAE KQQEDQSLLH TLSVYLETHC QISETAKRLY VHRNTVIYRL 500
EKCEELLGKS LKDPETTMRL RLALRMQRLI S 531
Length:531
Mass (Da):60,514
Last modified:January 1, 1998 - v1
Checksum:iCC2DA7F96247452F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL009126 Genomic DNA. Translation: CAB15232.1.
PIRiD70016.
RefSeqiNP_391122.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB15232; CAB15232; BSU32420.
GeneIDi937221.
KEGGibsu:BSU32420.
PATRICi18978456. VBIBacSub10457_3391.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL009126 Genomic DNA. Translation: CAB15232.1 .
PIRi D70016.
RefSeqi NP_391122.1. NC_000964.3.

3D structure databases

ProteinModelPortali O32138.
SMRi O32138. Positions 470-503.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224308.BSU32420.

Proteomic databases

PaxDbi O32138.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB15232 ; CAB15232 ; BSU32420 .
GeneIDi 937221.
KEGGi bsu:BSU32420.
PATRICi 18978456. VBIBacSub10457_3391.

Organism-specific databases

GenoListi BSU32420. [Micado ]

Phylogenomic databases

eggNOGi COG2508.
HOGENOMi HOG000009087.
KOi K09684.
OMAi RNEPVYI.
OrthoDBi EOG6038SW.
PhylomeDBi O32138.

Enzyme and pathway databases

BioCyci BSUB:BSU32420-MONOMER.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR009057. Homeodomain-like.
IPR025736. PucR_C-HTH_dom.
IPR012914. PucR_dom.
[Graphical view ]
Pfami PF13556. HTH_30. 1 hit.
PF07905. PucR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  2. "Functional analysis of 14 genes that constitute the purine catabolic pathway in Bacillus subtilis and evidence for a novel regulon controlled by the PucR transcription activator."
    Schultz A.C., Nygaard P., Saxild H.H.
    J. Bacteriol. 183:3293-3302(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Strain: 168.
  3. "Transcription analysis of the Bacillus subtilis PucR regulon and identification of a cis-acting sequence required for PucR-regulated expression of genes involved in purine catabolism."
    Beier L., Nygaard P., Jarmer H., Saxild H.H.
    J. Bacteriol. 184:3232-3241(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Strain: 168.

Entry informationi

Entry nameiPUCR_BACSU
AccessioniPrimary (citable) accession number: O32138
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi