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Protein

Ktr system potassium uptake protein B

Gene

ktrB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress.2 Publications

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Enzyme and pathway databases

BioCyciBSUB:BSU31100-MONOMER.

Protein family/group databases

TCDBi2.A.38.4.3. the k(+) transporter (trk) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Ktr system potassium uptake protein B
Short name:
K(+)-uptake protein KtrB
Gene namesi
Name:ktrB
Synonyms:yubG
Ordered Locus Names:BSU31100
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3921HelicalSequence analysisAdd
BLAST
Transmembranei46 – 6621HelicalSequence analysisAdd
BLAST
Transmembranei79 – 9921HelicalSequence analysisAdd
BLAST
Transmembranei127 – 14721HelicalSequence analysisAdd
BLAST
Transmembranei161 – 18121HelicalSequence analysisAdd
BLAST
Transmembranei196 – 21621HelicalSequence analysisAdd
BLAST
Transmembranei230 – 25021HelicalSequence analysisAdd
BLAST
Transmembranei286 – 30621HelicalSequence analysisAdd
BLAST
Transmembranei313 – 33321HelicalSequence analysisAdd
BLAST
Transmembranei351 – 37121HelicalSequence analysisAdd
BLAST
Transmembranei377 – 39721HelicalSequence analysisAdd
BLAST
Transmembranei408 – 42821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Impaired potassium uptake.1 Publication

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi436 – 44510Missing : Loss of homodimerization. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Ktr system potassium uptake protein BPRO_0000360618Add
BLAST

Proteomic databases

PaxDbiO32081.

Interactioni

Subunit structurei

Homodimer. Part of the KtrAB complex formed by an octameric catalytic ring of KtrA and a membrane associated dimer of KtrB forming a potassium channel.2 Publications

Protein-protein interaction databases

DIPiDIP-60210N.
STRINGi224308.Bsubs1_010100016911.

Structurei

Secondary structure

1
445
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi16 – 3621Combined sources
Helixi38 – 403Combined sources
Beta strandi41 – 433Combined sources
Helixi47 – 5812Combined sources
Helixi68 – 714Combined sources
Helixi74 – 8916Combined sources
Helixi91 – 10111Combined sources
Helixi108 – 11710Combined sources
Helixi126 – 14520Combined sources
Helixi148 – 1514Combined sources
Helixi161 – 17313Combined sources
Beta strandi180 – 1856Combined sources
Helixi186 – 1883Combined sources
Helixi192 – 20615Combined sources
Helixi209 – 21810Combined sources
Beta strandi220 – 2234Combined sources
Helixi226 – 25025Combined sources
Helixi254 – 2585Combined sources
Helixi264 – 27411Combined sources
Turni275 – 2795Combined sources
Helixi291 – 30212Combined sources
Beta strandi307 – 3104Combined sources
Helixi316 – 33015Combined sources
Helixi345 – 37228Combined sources
Helixi377 – 38812Combined sources
Helixi398 – 4003Combined sources
Helixi403 – 41816Combined sources
Helixi420 – 4245Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4J7CX-ray3.50I/J/K/L1-445[»]
5BUTX-ray5.97I/J/K/L1-445[»]
ProteinModelPortaliO32081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CZN. Bacteria.
COG0168. LUCA.
HOGENOMiHOG000277617.
InParanoidiO32081.
KOiK03498.
OMAiFGGIGYQ.
PhylomeDBiO32081.

Family and domain databases

InterProiIPR003445. Cat_transpt.
IPR004772. TrkH.
[Graphical view]
PfamiPF02386. TrkH. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00933. 2a38. 1 hit.

Sequencei

Sequence statusi: Complete.

O32081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLQKDKVIK WVRFTPPQVL AIGFFLTIII GAVLLMLPIS TTKPLSWIDA
60 70 80 90 100
LFTAASATTV TGLAVVDTGT QFTVFGQTVI MGLIQIGGLG FMTFAVLIVM
110 120 130 140 150
ILGKKIGLKE RMLVQEALNQ PTIGGVIGLV KVLFLFSISI ELIAALILSI
160 170 180 190 200
RLVPQYGWSS GLFASLFHAI SAFNNAGFSL WPDNLMSYVG DPTVNLVITF
210 220 230 240 250
LFITGGIGFT VLFDVMKNRR FKTFSLHTKL MLTGTLMLNA IAMLTVFILE
260 270 280 290 300
YSNPGTLGHL HIVDKLWASY FQAVTPRTAG FNSLDFGSMR EGTIVFTLLL
310 320 330 340 350
MFIGAGSAST ASGIKLTTFI VILTSVIAYL RGKKETVIFR RSIKYPIIIK
360 370 380 390 400
ALAVSVTSLF IVFLGIFALT ITEQAPFLQI VFETFSAFGT VGLTMGLTPE
410 420 430 440
LTTAGKCIII VIMFIGRIGP LTFVFSFAKT EQSNIRYPDG EVFTG
Length:445
Mass (Da):48,437
Last modified:January 1, 1998 - v1
Checksum:i94AFD060587FD117
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB15088.1.
PIRiB70007.
RefSeqiNP_390988.1. NC_000964.3.
WP_003243582.1. NZ_JNCM01000033.1.

Genome annotation databases

EnsemblBacteriaiCAB15088; CAB15088; BSU31100.
GeneIDi938835.
KEGGibsu:BSU31100.
PATRICi18978174. VBIBacSub10457_3251.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB15088.1.
PIRiB70007.
RefSeqiNP_390988.1. NC_000964.3.
WP_003243582.1. NZ_JNCM01000033.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4J7CX-ray3.50I/J/K/L1-445[»]
5BUTX-ray5.97I/J/K/L1-445[»]
ProteinModelPortaliO32081.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60210N.
STRINGi224308.Bsubs1_010100016911.

Protein family/group databases

TCDBi2.A.38.4.3. the k(+) transporter (trk) family.

Proteomic databases

PaxDbiO32081.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15088; CAB15088; BSU31100.
GeneIDi938835.
KEGGibsu:BSU31100.
PATRICi18978174. VBIBacSub10457_3251.

Phylogenomic databases

eggNOGiENOG4105CZN. Bacteria.
COG0168. LUCA.
HOGENOMiHOG000277617.
InParanoidiO32081.
KOiK03498.
OMAiFGGIGYQ.
PhylomeDBiO32081.

Enzyme and pathway databases

BioCyciBSUB:BSU31100-MONOMER.

Family and domain databases

InterProiIPR003445. Cat_transpt.
IPR004772. TrkH.
[Graphical view]
PfamiPF02386. TrkH. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00933. 2a38. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKTRB_BACSU
AccessioniPrimary (citable) accession number: O32081
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.