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Protein

Ktr system potassium uptake protein B

Gene

ktrB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress.2 Publications

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Enzyme and pathway databases

BioCyciBSUB:BSU31100-MONOMER.

Protein family/group databases

TCDBi2.A.38.4.3. the k(+) transporter (trk) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Ktr system potassium uptake protein B
Short name:
K(+)-uptake protein KtrB
Gene namesi
Name:ktrB
Synonyms:yubG
Ordered Locus Names:BSU31100
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Transmembranei46 – 66HelicalSequence analysisAdd BLAST21
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Transmembranei127 – 147HelicalSequence analysisAdd BLAST21
Transmembranei161 – 181HelicalSequence analysisAdd BLAST21
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Transmembranei230 – 250HelicalSequence analysisAdd BLAST21
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei313 – 333HelicalSequence analysisAdd BLAST21
Transmembranei351 – 371HelicalSequence analysisAdd BLAST21
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Transmembranei408 – 428HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Impaired potassium uptake.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi436 – 445Missing : Loss of homodimerization. 1 Publication10

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003606181 – 445Ktr system potassium uptake protein BAdd BLAST445

Proteomic databases

PaxDbiO32081.

Interactioni

Subunit structurei

Homodimer. Part of the KtrAB complex formed by an octameric catalytic ring of KtrA and a membrane associated dimer of KtrB forming a potassium channel.2 Publications

Protein-protein interaction databases

DIPiDIP-60210N.
STRINGi224308.Bsubs1_010100016911.

Structurei

Secondary structure

1445
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi16 – 36Combined sources21
Helixi38 – 40Combined sources3
Beta strandi41 – 43Combined sources3
Helixi47 – 58Combined sources12
Helixi68 – 71Combined sources4
Helixi74 – 89Combined sources16
Helixi91 – 101Combined sources11
Helixi108 – 117Combined sources10
Helixi126 – 145Combined sources20
Helixi148 – 151Combined sources4
Helixi161 – 173Combined sources13
Beta strandi180 – 185Combined sources6
Helixi186 – 188Combined sources3
Helixi192 – 206Combined sources15
Helixi209 – 218Combined sources10
Beta strandi220 – 223Combined sources4
Helixi226 – 250Combined sources25
Helixi254 – 258Combined sources5
Helixi264 – 274Combined sources11
Turni275 – 279Combined sources5
Helixi291 – 302Combined sources12
Beta strandi307 – 310Combined sources4
Helixi316 – 330Combined sources15
Helixi345 – 372Combined sources28
Helixi377 – 388Combined sources12
Helixi398 – 400Combined sources3
Helixi403 – 418Combined sources16
Helixi420 – 424Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4J7CX-ray3.50I/J/K/L1-445[»]
5BUTX-ray5.97I/J/K/L1-445[»]
ProteinModelPortaliO32081.
SMRiO32081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CZN. Bacteria.
COG0168. LUCA.
HOGENOMiHOG000277617.
InParanoidiO32081.
KOiK03498.
OMAiFGGIGYQ.
PhylomeDBiO32081.

Family and domain databases

InterProiIPR003445. Cat_transpt.
IPR004772. TrkH.
[Graphical view]
PfamiPF02386. TrkH. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00933. 2a38. 1 hit.

Sequencei

Sequence statusi: Complete.

O32081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLQKDKVIK WVRFTPPQVL AIGFFLTIII GAVLLMLPIS TTKPLSWIDA
60 70 80 90 100
LFTAASATTV TGLAVVDTGT QFTVFGQTVI MGLIQIGGLG FMTFAVLIVM
110 120 130 140 150
ILGKKIGLKE RMLVQEALNQ PTIGGVIGLV KVLFLFSISI ELIAALILSI
160 170 180 190 200
RLVPQYGWSS GLFASLFHAI SAFNNAGFSL WPDNLMSYVG DPTVNLVITF
210 220 230 240 250
LFITGGIGFT VLFDVMKNRR FKTFSLHTKL MLTGTLMLNA IAMLTVFILE
260 270 280 290 300
YSNPGTLGHL HIVDKLWASY FQAVTPRTAG FNSLDFGSMR EGTIVFTLLL
310 320 330 340 350
MFIGAGSAST ASGIKLTTFI VILTSVIAYL RGKKETVIFR RSIKYPIIIK
360 370 380 390 400
ALAVSVTSLF IVFLGIFALT ITEQAPFLQI VFETFSAFGT VGLTMGLTPE
410 420 430 440
LTTAGKCIII VIMFIGRIGP LTFVFSFAKT EQSNIRYPDG EVFTG
Length:445
Mass (Da):48,437
Last modified:January 1, 1998 - v1
Checksum:i94AFD060587FD117
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB15088.1.
PIRiB70007.
RefSeqiNP_390988.1. NC_000964.3.
WP_003243582.1. NZ_JNCM01000033.1.

Genome annotation databases

EnsemblBacteriaiCAB15088; CAB15088; BSU31100.
GeneIDi938835.
KEGGibsu:BSU31100.
PATRICi18978174. VBIBacSub10457_3251.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB15088.1.
PIRiB70007.
RefSeqiNP_390988.1. NC_000964.3.
WP_003243582.1. NZ_JNCM01000033.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4J7CX-ray3.50I/J/K/L1-445[»]
5BUTX-ray5.97I/J/K/L1-445[»]
ProteinModelPortaliO32081.
SMRiO32081.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60210N.
STRINGi224308.Bsubs1_010100016911.

Protein family/group databases

TCDBi2.A.38.4.3. the k(+) transporter (trk) family.

Proteomic databases

PaxDbiO32081.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15088; CAB15088; BSU31100.
GeneIDi938835.
KEGGibsu:BSU31100.
PATRICi18978174. VBIBacSub10457_3251.

Phylogenomic databases

eggNOGiENOG4105CZN. Bacteria.
COG0168. LUCA.
HOGENOMiHOG000277617.
InParanoidiO32081.
KOiK03498.
OMAiFGGIGYQ.
PhylomeDBiO32081.

Enzyme and pathway databases

BioCyciBSUB:BSU31100-MONOMER.

Family and domain databases

InterProiIPR003445. Cat_transpt.
IPR004772. TrkH.
[Graphical view]
PfamiPF02386. TrkH. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00933. 2a38. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKTRB_BACSU
AccessioniPrimary (citable) accession number: O32081
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.