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Protein

Putative serine/threonine-protein kinase YrzF

Gene

yrzF

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei54 – 541ATPBy similarity
Active sitei135 – 1351Proton acceptorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi33 – 419ATPBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU27785-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein kinase YrzF (EC:2.7.11.1)
Gene namesi
Name:yrzF
Ordered Locus Names:BSU27785
ORF Names:BSU27780
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215Putative serine/threonine-protein kinase YrzFPRO_0000387941Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO32057.
SMRiO32057. Positions 24-205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini27 – 215189Protein kinaseAdd
BLAST

Sequence similaritiesi

Contains 1 protein kinase domain.Curated

Phylogenomic databases

HOGENOMiHOG000011094.
InParanoidiO32057.
OMAiLAHSVIY.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR017441. Protein_kinase_ATP_BS.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O32057-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTKAEALAH TVIYRKNSRF DKVKEKSEEL TLIGKGRSAY VFALTEGGRK
60 70 80 90 100
MALKVFFPEY QATAVKEAAI YEKLAGSAFY PDIYETGDSF ILMEYIKGET
110 120 130 140 150
FYNCLKKGIA ISDDMIQQVE EALSDARAAG LNPSDIHLRN LILTETGAVR
160 170 180 190 200
VIDVARFEQT KTCTQWDDLK SAYHALYKKP IFPKKIPGFW LEIIAFLYKK
210
DWFQKHFAQR KRKYS
Length:215
Mass (Da):24,720
Last modified:May 5, 2009 - v2
Checksum:i9C019DDEFE44490F
GO

Sequence cautioni

The sequence CAB75326 differs from that shown. Reason: Frameshift at position 127. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y15896 Genomic DNA. Translation: CAB75326.1. Frameshift.
AL009126 Genomic DNA. Translation: CAB14738.2.
PIRiE69982.
RefSeqiNP_390656.2. NC_000964.3.
WP_003246159.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14738; CAB14738; BSU27785.
GeneIDi936570.
KEGGibsu:BSU27785.
PATRICi18977424. VBIBacSub10457_2901.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y15896 Genomic DNA. Translation: CAB75326.1. Frameshift.
AL009126 Genomic DNA. Translation: CAB14738.2.
PIRiE69982.
RefSeqiNP_390656.2. NC_000964.3.
WP_003246159.1. NZ_JNCM01000036.1.

3D structure databases

ProteinModelPortaliO32057.
SMRiO32057. Positions 24-205.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14738; CAB14738; BSU27785.
GeneIDi936570.
KEGGibsu:BSU27785.
PATRICi18977424. VBIBacSub10457_2901.

Phylogenomic databases

HOGENOMiHOG000011094.
InParanoidiO32057.
OMAiLAHSVIY.

Enzyme and pathway databases

BioCyciBSUB:BSU27785-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR017441. Protein_kinase_ATP_BS.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYRZF_BACSU
AccessioniPrimary (citable) accession number: O32057
Secondary accession number(s): C0SPA9, Q799D9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: September 7, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.