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Protein

Putative N-acetylmuramoyl-L-alanine amidase YrvJ

Gene

yrvJ

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably involved in cell-wall metabolism.By similarity

Catalytic activityi

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. N-acetylmuramoyl-L-alanine amidase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Cell wall biogenesis/degradation

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciBSUB:BSU27580-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative N-acetylmuramoyl-L-alanine amidase YrvJ (EC:3.5.1.28)
Gene namesi
Name:yrvJ
Ordered Locus Names:BSU27580
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570 Componenti: Chromosome

Organism-specific databases

GenoListiBSU27580.

Subcellular locationi

  1. Secretedcell wall By similarity

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence AnalysisAdd
BLAST
Chaini28 – 518491Putative N-acetylmuramoyl-L-alanine amidase YrvJPRO_0000360805Add
BLAST

Proteomic databases

PaxDbiO32041.

Interactioni

Protein-protein interaction databases

STRINGi224308.BSU27580.

Structurei

3D structure databases

ProteinModelPortaliO32041.
SMRiO32041. Positions 29-166, 181-320, 344-518.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0860.
HOGENOMiHOG000018078.
InParanoidiO32041.
KOiK01448.
OMAiTSHYRNA.
OrthoDBiEOG6CP3X3.
PhylomeDBiO32041.

Family and domain databases

Gene3Di3.40.630.40. 1 hit.
InterProiIPR002508. CW_Hdrlase/autolysin_cat.
IPR003646. SH3-like_bac-type.
[Graphical view]
PfamiPF01520. Amidase_3. 1 hit.
PF08239. SH3_3. 4 hits.
[Graphical view]
SMARTiSM00646. Ami_3. 1 hit.
SM00287. SH3b. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O32041-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKKYFVLIV CIIFTSALFP TFSSVTAAQG EAVIATDEMN VRSGPGLSYG
60 70 80 90 100
ITAEVKKGER YPILKEDGDW VQIQLGSGEK GWVVSWLITK EDQASTSSSG
110 120 130 140 150
SSDTVTSTDP DLRMRSGPGT SYEVIGKFPQ GSQASVIDKD SGWIKISYHS
160 170 180 190 200
ATGWVSSEYV TSGGSSSASD ESDQTEDSGA STTGTVGVSS LNVRASASHD
210 220 230 240 250
AAIITKLDRG TKLTVLNEKN GWAHIEVNGL KGWVASHYLL TSSVPADDSA
260 270 280 290 300
NAGSSSSAKK AYIMYGGTNL RSDASTSASI VERAAKGDSY TITGSKGSWY
310 320 330 340 350
EIKLDNGQTA YVANWVVQTS KSAEEAGEPP VSDSPSGNGS LNNKTIIVDP
360 370 380 390 400
GHGGKDSGTI GYSGKFEKNL TIKTAKLLAS KLRSAGADVY VTRQDDTFVS
410 420 430 440 450
LQSRVSTSHY RNADAFISIH YDSYADTSTR GSTAYYYSPA KDQELASDVH
460 470 480 490 500
SEVVKRSSIP DRGVLFGDYY VLRENRQPAM LYELGYVSHP QEEAIVHSNS
510
YQEKVTDGIE SGLEKYFQ
Length:518
Mass (Da):55,501
Last modified:January 1, 1998 - v1
Checksum:i8FE642A3D7724135
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB14717.1.
PIRiB69981.
RefSeqiNP_390636.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB14717; CAB14717; BSU27580.
GeneIDi937544.
KEGGibsu:BSU27580.
PATRICi18977380. VBIBacSub10457_2879.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA. Translation: CAB14717.1.
PIRiB69981.
RefSeqiNP_390636.1. NC_000964.3.

3D structure databases

ProteinModelPortaliO32041.
SMRiO32041. Positions 29-166, 181-320, 344-518.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.BSU27580.

Proteomic databases

PaxDbiO32041.

Protocols and materials databases

DNASUi937544.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14717; CAB14717; BSU27580.
GeneIDi937544.
KEGGibsu:BSU27580.
PATRICi18977380. VBIBacSub10457_2879.

Organism-specific databases

GenoListiBSU27580.

Phylogenomic databases

eggNOGiCOG0860.
HOGENOMiHOG000018078.
InParanoidiO32041.
KOiK01448.
OMAiTSHYRNA.
OrthoDBiEOG6CP3X3.
PhylomeDBiO32041.

Enzyme and pathway databases

BioCyciBSUB:BSU27580-MONOMER.

Family and domain databases

Gene3Di3.40.630.40. 1 hit.
InterProiIPR002508. CW_Hdrlase/autolysin_cat.
IPR003646. SH3-like_bac-type.
[Graphical view]
PfamiPF01520. Amidase_3. 1 hit.
PF08239. SH3_3. 4 hits.
[Graphical view]
SMARTiSM00646. Ami_3. 1 hit.
SM00287. SH3b. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.

Entry informationi

Entry nameiYRVJ_BACSU
AccessioniPrimary (citable) accession number: O32041
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: April 1, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.