O31332 (MURI_BACC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Synonyms:	glr, racE
Ordered Locus Names:	BCE_4589

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	Glutamate racemase HAMAP MF_00258		PRO_0000095450
Experimental info
	Sequence conflict	74	1	C → M in CAA70886. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	O31332 [UniParc]. Last modified May 24, 2004. Version 2. Checksum: 775FC8F3E98807BD	FASTA	269	29,967
	10 20 30 40 50 60 MKLNRAIGVI DSGVGGLTVA KELIRQLPKE RIIYLGDTAR CPYGPRSREE VRQFTWEMTE 70 80 90 100 110 120 HLLDLNIKML VIACNTATAV VLEEMQKQLP IPVVGVIHPG SRTALKMTNT YHVGIIGTIG 130 140 150 160 170 180 TVKSGAYEEA LKSINNRVMV ESLACPPFVE LVESGNFESE MAYEVVRETL QPLKNTDIDT 190 200 210 220 230 240 LILGCTHYPI LGPVIKQVMG DKVQLISSGD ETAREVSTIL YHSKMLNEGE EQSDHLFLTT 250 260 GKIGLFKEIA SKWFGQPIEN VKHIYLEKE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Insertional inactivation of a Tet(K)/Tet(L) like transporter does not eliminate tetracycline resistance in Bacillus cereus." Oekstad O.A., Groenstad A., Lindbaeck T., Kolstoe A.-B. FEMS Microbiol. Lett. 154:181-186(1997) [PubMed: 9311114] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10987.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y09719 mRNA. Translation: CAA70886.1. AE017194 Genomic DNA. Translation: AAS43490.1.
RefSeq	NP_980882.1. NC_003909.8.
3D structure databases
ProteinModelPortal	O31332.
SMR	O31332. Positions 2-267.
ModBase	Search...
Protein-protein interaction databases
STRING	O31332.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000027793; EBBACP00000027143; EBBACG00000027784.
GeneID	2751152.
GenomeReviews	Gene locus BCE_4589 in contig AE017194_GR.
KEGG	bca:BCE_4589.
NMPDR	fig|222523.1.peg.4554.
PATRIC	18857802. VBIBacCer118379_4396.
TIGR	BCE_4589.
Phylogenomic databases
eggNOG	COG0796.
GeneTree	EBGT00050000002346.
HOGENOM	HBG645102.
OMA	PQEDTIY.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	BCER405917:BCE_4589-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BACC1

Accession

Primary (citable) accession number: O31332

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 24, 2004
Last modified:	January 25, 2012
This is version 83 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program