ID   PRXC_STRAU              Reviewed;         278 AA.
AC   O31168;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   16-JUN-2009, entry version 59.
DE   RecName: Full=Non-heme chloroperoxidase;
DE            EC=1.11.1.10;
DE   AltName: Full=Chloride peroxidase;
DE   AltName: Full=Chloroperoxidase T;
DE            Short=CPO-T;
GN   Name=cpo; Synonyms=cpoT;
OS   Streptomyces aureofaciens.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptomycineae; Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1894;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Tu24;
RA   Pelletier I., Altenbuchner J., van Pee K.-H.;
RL   Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).
RC   STRAIN=Tu24;
RX   MEDLINE=98307994; PubMed=9642069; DOI=10.1006/jmbi.1998.1802;
RA   Hofmann B., Tolzer S., Pelletier I., Altenbuchner J., van Pee K.-H.,
RA   Hecht H.-J.;
RT   "Structural investigation of the cofactor-free chloroperoxidases.";
RL   J. Mol. Biol. 279:889-900(1998).
CC   -!- CATALYTIC ACTIVITY: RH + Cl(-) + H(2)O(2) = RCl + 2 H(2)O.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the bacterial non-heme bromo- and chloro-
CC       peroxidases family.
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DR   EMBL; AF031242; AAB86626.1; -; Genomic_DNA.
DR   PDB; 1A7U; X-ray; 1.75 A; A/B=2-278.
DR   PDB; 1A8U; X-ray; 1.60 A; A/B=2-278.
DR   PDBsum; 1A7U; -.
DR   PDBsum; 1A8U; -.
DR   MEROPS; S33.991; -.
DR   PeroxiBase; 5908; STaHalNPrx02.
DR   BRENDA; 1.11.1.10; 2126.
DR   GO; GO:0031404; F:chloride ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016691; F:chloride peroxidase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Chloride; Oxidoreductase; Peroxidase.
FT   CHAIN         1    278       Non-heme chloroperoxidase.
FT                                /FTId=PRO_0000207062.
FT   ACT_SITE     99     99       By similarity.
FT   ACT_SITE    229    229       By similarity.
FT   ACT_SITE    258    258       By similarity.
FT   STRAND        3      9
FT   STRAND       12     30
FT   HELIX        37     40
FT   HELIX        41     49
FT   STRAND       53     57
FT   HELIX        74     88
FT   STRAND       92     98
FT   HELIX       101    112
FT   STRAND      117    124
FT   STRAND      139    141
FT   HELIX       143    155
FT   HELIX       157    168
FT   HELIX       171    174
FT   TURN        176    178
FT   HELIX       181    193
FT   HELIX       196    205
FT   TURN        211    213
FT   HELIX       214    216
FT   STRAND      221    226
FT   STRAND      230    232
FT   HELIX       234    236
FT   HELIX       238    244
FT   STRAND      248    253
FT   HELIX       260    263
FT   HELIX       265    277
SQ   SEQUENCE   278 AA;  30355 MW;  8C97A87251FBEDE5 CRC64;
     MPFITVGQEN STSIDLYYED HGAGQPVVLI HGFPLSGHSW ERQSAALLDA GYRVITYDRR
     GFGQSSQPTT GYDYDTFAAD LNTVLETLDL QDAVLVGFSM GTGEVARYVS SYGTARIAKV
     AFLASLEPFL LKTDDNPDGA APKEFFDGIV AAVKADRYAF YTGFFNDFYN LDENLGTRIS
     EEAVRNSWNT AASGGFFAAA AAPTTWYTDF RADIPRIDVP ALILHGTGDR TLPIENTARV
     FHKALPSAEY VEVEGAPHGL LWTHAEEVNT ALLAFLAK
//