O31038 (MSUE_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
FMN reductase (NADPH)
EC=1.5.1.38

Alternative name(s):
FMN reductase

Gene names

Name:	msuE
Synonyms:	slfA
Ordered Locus Names:	PA2357

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

Taxonomic identifier

208964 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	FMNH2 + NADP+ = FMN + NADPH.
Sequence similarities	Belongs to the ssuE family.

Ontologies

Keywords
Ligand	FMN NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	FMN reductase (NADPH)		PRO_0000160594

Sequences

	Sequence		Length	Mass (Da)
	O31038 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 752453F9A832ED3C	FASTA	186	20,028
	10 20 30 40 50 60 MTSPFKVVAV SGGTYRPSRT LVLTQALIAE LGQSLPIDSR VIELTDIAAP LGATLARNQA 70 80 90 100 110 120 PAELQAVLDE IESADLLLVA SPVYRGSYPG LLKHLFDLID LNALIDTPVL LAATGGTERH 130 140 150 160 170 180 ALVLDHQLRP LFSFFQAITL PIGVYASEAD FDNYRIVSEP LKARIRLAAE RAAPLFGGRS ELLKIA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A novel reduced flavin mononucleotide-dependent methanesulfonate sulfonatase encoded by the sulfur-regulated msu operon of Pseudomonas aeruginosa." Kertesz M.A., Schmidt-Larbig K., Wueest T. J. Bacteriol. 181:1464-1473(1999) [PubMed: 10049377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]	"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V. Nature 406:959-964(2000) [PubMed: 10984043] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF026067 Genomic DNA. Translation: AAB82563.1. AE004091 Genomic DNA. Translation: AAG05745.1.
PIR	F83352.
RefSeq	NP_251047.1. NC_002516.2.
3D structure databases
ProteinModelPortal	O31038.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	882283.
GenomeReviews	Gene locus PA2357 in contig AE004091_GR.
KEGG	pae:PA2357.
PATRIC	19839173. VBIPseAer58763_2466.
Organism-specific databases
PseudoCAP	PA2357.
Phylogenomic databases
HOGENOM	HBG697130.
OMA	TWRPSRT.
ProtClustDB	CLSK867202.
Enzyme and pathway databases
BioCyc	PAER208964:PA2357-MONOMER.
Family and domain databases
InterPro	IPR019912. FMN_Rdtase_MsuE-like. IPR005025. FMN_red. [Graphical view]
KO	K00299.
Pfam	PF03358. FMN_red. 1 hit. [Graphical view]
TIGRFAMs	TIGR03566. FMN_reduc_MsuE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSUE_PSEAE

Accession

Primary (citable) accession number: O31038

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	January 1, 1998
Last modified:	January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program