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O30869

- T2H2_HAEAE

UniProt

O30869 - T2H2_HAEAE

Protein

Type-2 restriction enzyme HaeII

Gene

haeIIR

Organism
Haemophilus aegyptius
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 45 (16 Apr 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Recognizes the double-stranded sequence RGCGCY and cleaves after C-5.

    Catalytic activityi

    Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

    GO - Molecular functioni

    1. Type II site-specific deoxyribonuclease activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    Restriction system

    Protein family/group databases

    REBASEi1088. HaeII.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type-2 restriction enzyme HaeII (EC:3.1.21.4)
    Short name:
    R.HaeII
    Alternative name(s):
    Endonuclease HaeII
    Type II restriction enzyme HaeII
    Gene namesi
    Name:haeIIR
    Synonyms:dcrA
    OrganismiHaemophilus aegyptius
    Taxonomic identifieri197575 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 352352Type-2 restriction enzyme HaeIIPRO_0000077316Add
    BLAST

    Family & Domainsi

    Family and domain databases

    InterProiIPR019058. Restrct_endonuc_II_HaeII.
    [Graphical view]
    PfamiPF09554. RE_HaeII. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O30869-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNDIQVAKES LDKIIKKARV HLYKPIQIAE ILYQDRVNKN INLLDKETYR    50
    NISKKWRDVI CIRFLGRVST SSAKYQDDLF NDNAMPPKHL NILGEMNRKT 100
    NGGVESYIYK KFFERFNQMS SALEYSYSRT PDNFHLSEFL ALFWLEPGLK 150
    RSIDKVYEIV VYALFSSLIE ALGVKVKIDL DLSNIDLLKE FEDFTRQIIS 200
    LDSENTSLEL NAKINRVGVT NASDRGLDMW ANFGMAIQIK HLSLTEELAE 250
    NIVSSVSSDR IVIVCKESEE KLILSLLNQI GWRSKIQSII TEADLIKWYD 300
    KALRGKSAYL VGSKILEHIR NEINLEFPAT DIVDFNHFFH EREYNKALDI 350
    EK 352
    Length:352
    Mass (Da):40,801
    Last modified:January 1, 1998 - v1
    Checksum:i3AE01F59FB1C289A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF019752 Genomic DNA. Translation: AAB70830.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF019752 Genomic DNA. Translation: AAB70830.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 1088. HaeII.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR019058. Restrct_endonuc_II_HaeII.
    [Graphical view ]
    Pfami PF09554. RE_HaeII. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence similarities between the genes encoding the S.NgoI and HaeII restriction/modification systems."
      Stein D.C., Gunn J.S., Piekarowicz A.
      Biol. Chem. 379:575-578(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 11116 / CCUG 25716 / NCTC 8502.

    Entry informationi

    Entry nameiT2H2_HAEAE
    AccessioniPrimary (citable) accession number: O30869
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: January 1, 1998
    Last modified: April 16, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Restriction enzymes and methylases
      Classification of restriction enzymes and methylases and list of entries

    External Data

    Dasty 3