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Protein

Type-2 restriction enzyme HaeII

Gene

haeIIR

Organism
Haemophilus aegyptius
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Recognizes the double-stranded sequence RGCGCY and cleaves after C-5.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processRestriction system

Protein family/group databases

REBASEi1088 HaeII

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme HaeII (EC:3.1.21.4)
Short name:
R.HaeII
Alternative name(s):
Endonuclease HaeII
Type II restriction enzyme HaeII
Gene namesi
Name:haeIIR
Synonyms:dcrA
OrganismiHaemophilus aegyptius
Taxonomic identifieri197575 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000773161 – 352Type-2 restriction enzyme HaeIIAdd BLAST352

Proteomic databases

PRIDEiO30869

Structurei

3D structure databases

SMRiO30869
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiView protein in InterPro
IPR019058 Restrct_endonuc_II_HaeII
PfamiView protein in Pfam
PF09554 RE_HaeII, 1 hit

Sequencei

Sequence statusi: Complete.

O30869-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDIQVAKES LDKIIKKARV HLYKPIQIAE ILYQDRVNKN INLLDKETYR
60 70 80 90 100
NISKKWRDVI CIRFLGRVST SSAKYQDDLF NDNAMPPKHL NILGEMNRKT
110 120 130 140 150
NGGVESYIYK KFFERFNQMS SALEYSYSRT PDNFHLSEFL ALFWLEPGLK
160 170 180 190 200
RSIDKVYEIV VYALFSSLIE ALGVKVKIDL DLSNIDLLKE FEDFTRQIIS
210 220 230 240 250
LDSENTSLEL NAKINRVGVT NASDRGLDMW ANFGMAIQIK HLSLTEELAE
260 270 280 290 300
NIVSSVSSDR IVIVCKESEE KLILSLLNQI GWRSKIQSII TEADLIKWYD
310 320 330 340 350
KALRGKSAYL VGSKILEHIR NEINLEFPAT DIVDFNHFFH EREYNKALDI

EK
Length:352
Mass (Da):40,801
Last modified:January 1, 1998 - v1
Checksum:i3AE01F59FB1C289A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF019752 Genomic DNA Translation: AAB70830.1
RefSeqiWP_065250747.1, NZ_LZPG01000012.1

Similar proteinsi

Entry informationi

Entry nameiT2H2_HAEAE
AccessioniPrimary (citable) accession number: O30869
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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