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O30853

- KPYK1_PHOLE

UniProt

O30853 - KPYK1_PHOLE

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Protein
Pyruvate kinase I
Gene
pki
Organism
Photobacterium leiognathi
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactori

Magnesium.
Potassium.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei10 – 101Substrate; via amide nitrogen By similarity
Metal bindingi11 – 111Magnesium By similarity
Binding sitei11 – 111Substrate; via amide nitrogen By similarity
Binding sitei43 – 431Substrate By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. magnesium ion binding Source: InterPro
  3. potassium ion binding Source: InterPro
  4. pyruvate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium, Pyruvate

Enzyme and pathway databases

UniPathwayiUPA00109; UER00188.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinase I (EC:2.7.1.40)
Alternative name(s):
PK-1
Gene namesi
Name:pki
OrganismiPhotobacterium leiognathi
Taxonomic identifieri553611 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 235›235Pyruvate kinase I
PRO_0000112083Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.

Structurei

3D structure databases

ProteinModelPortaliO30853.
SMRiO30853. Positions 1-235.

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate kinase family.

Family and domain databases

Gene3Di3.20.20.60. 1 hit.
3.40.1380.20. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015794. Pyrv_Knase_a/b.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSiPR01050. PYRUVTKNASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
SSF52935. SSF52935. 1 hit.

Sequencei

Sequence statusi: Fragment.

O30853-1 [UniParc]FASTAAdd to Basket

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ASDGIMVARG DLGVEIPVEE VIFAQKMMIE KCNRARKVVI TATQMLDSMI    50
KNPRPTRAEA GDVANAIMDG TDAVMLSGES AKGKYPIEAV TIMAQICART 100
DDVVKPELGS RLDSPRLRIT EAVCKGAVDT AEKLNAPLII VATEAGKSAR 150
SVRKYFPTAR ILAVTTNTKT AAQLCLSKGV TPVVVDSIES TDAFYLRGKE 200
LALETGLGAK GDIVVMVSGA LVASGTTNTA SVHVL 235
Length:235
Mass (Da):24,734
Last modified:January 1, 1998 - v1
Checksum:iF805606C4C8EF4C1
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF019143 Genomic DNA. Translation: AAC45776.1.
PIRiPC4418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF019143 Genomic DNA. Translation: AAC45776.1 .
PIRi PC4418.

3D structure databases

ProteinModelPortali O30853.
SMRi O30853. Positions 1-235.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00188 .

Family and domain databases

Gene3Di 3.20.20.60. 1 hit.
3.40.1380.20. 1 hit.
InterProi IPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015794. Pyrv_Knase_a/b.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
[Graphical view ]
PANTHERi PTHR11817. PTHR11817. 1 hit.
Pfami PF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view ]
PRINTSi PR01050. PYRUVTKNASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
SSF52935. SSF52935. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The pkI gene encoding pyruvate kinase I links to the luxZ gene which enhances bioluminescence of the lux operon from Photobacterium leiognathi."
    Lin J.-W., Lu H.-C., Chen H.-Y., Weng S.-F.
    Biochem. Biophys. Res. Commun. 239:228-234(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 25521 / L1 / CIP 665.

Entry informationi

Entry nameiKPYK1_PHOLE
AccessioniPrimary (citable) accession number: O30853
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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