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O30853

- KPYK1_PHOLE

UniProt

O30853 - KPYK1_PHOLE

Protein

Pyruvate kinase I

Gene

pki

Organism
Photobacterium leiognathi
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + pyruvate = ADP + phosphoenolpyruvate.

    Cofactori

    Magnesium.
    Potassium.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei10 – 101Substrate; via amide nitrogenBy similarity
    Metal bindingi11 – 111MagnesiumBy similarity
    Binding sitei11 – 111Substrate; via amide nitrogenBy similarity
    Binding sitei43 – 431SubstrateBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. magnesium ion binding Source: InterPro
    3. potassium ion binding Source: InterPro
    4. pyruvate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium, Pyruvate

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00188.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate kinase I (EC:2.7.1.40)
    Alternative name(s):
    PK-1
    Gene namesi
    Name:pki
    OrganismiPhotobacterium leiognathi
    Taxonomic identifieri553611 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 235›235Pyruvate kinase IPRO_0000112083Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO30853.
    SMRiO30853. Positions 1-235.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pyruvate kinase family.Curated

    Family and domain databases

    Gene3Di3.20.20.60. 1 hit.
    3.40.1380.20. 1 hit.
    InterProiIPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR015794. Pyrv_Knase_a/b.
    IPR015793. Pyrv_Knase_brl.
    IPR015795. Pyrv_Knase_C.
    [Graphical view]
    PANTHERiPTHR11817. PTHR11817. 1 hit.
    PfamiPF00224. PK. 1 hit.
    PF02887. PK_C. 1 hit.
    [Graphical view]
    PRINTSiPR01050. PYRUVTKNASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    SSF52935. SSF52935. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    O30853-1 [UniParc]FASTAAdd to Basket

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    ASDGIMVARG DLGVEIPVEE VIFAQKMMIE KCNRARKVVI TATQMLDSMI    50
    KNPRPTRAEA GDVANAIMDG TDAVMLSGES AKGKYPIEAV TIMAQICART 100
    DDVVKPELGS RLDSPRLRIT EAVCKGAVDT AEKLNAPLII VATEAGKSAR 150
    SVRKYFPTAR ILAVTTNTKT AAQLCLSKGV TPVVVDSIES TDAFYLRGKE 200
    LALETGLGAK GDIVVMVSGA LVASGTTNTA SVHVL 235
    Length:235
    Mass (Da):24,734
    Last modified:January 1, 1998 - v1
    Checksum:iF805606C4C8EF4C1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF019143 Genomic DNA. Translation: AAC45776.1.
    PIRiPC4418.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF019143 Genomic DNA. Translation: AAC45776.1 .
    PIRi PC4418.

    3D structure databases

    ProteinModelPortali O30853.
    SMRi O30853. Positions 1-235.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00188 .

    Family and domain databases

    Gene3Di 3.20.20.60. 1 hit.
    3.40.1380.20. 1 hit.
    InterProi IPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR015794. Pyrv_Knase_a/b.
    IPR015793. Pyrv_Knase_brl.
    IPR015795. Pyrv_Knase_C.
    [Graphical view ]
    PANTHERi PTHR11817. PTHR11817. 1 hit.
    Pfami PF00224. PK. 1 hit.
    PF02887. PK_C. 1 hit.
    [Graphical view ]
    PRINTSi PR01050. PYRUVTKNASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    SSF52935. SSF52935. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The pkI gene encoding pyruvate kinase I links to the luxZ gene which enhances bioluminescence of the lux operon from Photobacterium leiognathi."
      Lin J.-W., Lu H.-C., Chen H.-Y., Weng S.-F.
      Biochem. Biophys. Res. Commun. 239:228-234(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 25521 / L1 / CIP 665.

    Entry informationi

    Entry nameiKPYK1_PHOLE
    AccessioniPrimary (citable) accession number: O30853
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3