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O30853 (KPYK1_PHOLE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate kinase I

EC=2.7.1.40
Alternative name(s):
PK-1
Gene names
Name:pki
OrganismPhotobacterium leiognathi
Taxonomic identifier553611 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium

Protein attributes

Sequence length235 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactor

Magnesium.

Potassium.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the pyruvate kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 235›235Pyruvate kinase I
PRO_0000112083

Sites

Metal binding111Magnesium By similarity
Binding site101Substrate; via amide nitrogen By similarity
Binding site111Substrate; via amide nitrogen By similarity
Binding site431Substrate By similarity

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
O30853 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: F805606C4C8EF4C1

FASTA23524,734
        10         20         30         40         50         60 
ASDGIMVARG DLGVEIPVEE VIFAQKMMIE KCNRARKVVI TATQMLDSMI KNPRPTRAEA 

        70         80         90        100        110        120 
GDVANAIMDG TDAVMLSGES AKGKYPIEAV TIMAQICART DDVVKPELGS RLDSPRLRIT 

       130        140        150        160        170        180 
EAVCKGAVDT AEKLNAPLII VATEAGKSAR SVRKYFPTAR ILAVTTNTKT AAQLCLSKGV 

       190        200        210        220        230 
TPVVVDSIES TDAFYLRGKE LALETGLGAK GDIVVMVSGA LVASGTTNTA SVHVL 

« Hide

References

[1]"The pkI gene encoding pyruvate kinase I links to the luxZ gene which enhances bioluminescence of the lux operon from Photobacterium leiognathi."
Lin J.-W., Lu H.-C., Chen H.-Y., Weng S.-F.
Biochem. Biophys. Res. Commun. 239:228-234(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 25521 / L1 / CIP 665.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF019143 Genomic DNA. Translation: AAC45776.1.
PIRPC4418.

3D structure databases

ProteinModelPortalO30853.
SMRO30853. Positions 1-235.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Family and domain databases

Gene3D3.20.20.60. 1 hit.
3.40.1380.20. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015794. Pyrv_Knase_a/b.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
SUPFAMSSF51621. SSF51621. 1 hit.
SSF52935. SSF52935. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKPYK1_PHOLE
AccessionPrimary (citable) accession number: O30853
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways