O30847 (CLCE_PSESB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Maleylacetate reductase
EC=1.3.1.32

Gene names

Name:

clcE

Organism

Pseudomonas sp. (strain B13)

Taxonomic identifier

65741 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H.
Pathway	Aromatic compound metabolism; 3-chlorocatechol degradation.
Sequence similarities	Belongs to the iron-containing alcohol dehydrogenase family.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Plasmid
Gene Ontology (GO)
Biological process	aromatic compound catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	maleylacetate reductase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 352	352	Maleylacetate reductase		PRO_0000087846

Sequences

	Sequence		Length	Mass (Da)
	O30847 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: D4DBFDD69D990E79	FASTA	352	37,769
	10 20 30 40 50 60 MNFIHDYRSP RVIFGPDSLA RLPQELERLG IDRALVLTTP EQAPLGRQVA EPVIGHVAAF 70 80 90 100 110 120 YDGATMHVPA LVAEEACKIA RTSEANGVIA IGGGSTIGLA KIVALRTELP IVAVPTTYAG 130 140 150 160 170 180 SEMTSIFGIT EGGVKKTGRD ARVMPRAVIY EPRLTLELPL SISVTSAINA IAHAVEGLYA 190 200 210 220 230 240 PDATPLLTIM AQEGIAATVR AISRMYQSPR DLQARGDALY GAWLCASVLG NVSMALHHKL 250 260 270 280 290 300 CHTLGGTLDL PHAQTHTVVL PHALAYNARA VPDAMRVLRI ALGHDDPPTA LYELARDNGA 310 320 330 340 350 PVALRDLGMR EEDIEHVGDL ALQDRYPNPR ELDRDALLAL LRDAYHGRPP SA

References

[1]	"Cloning, characterization, and sequence analysis of the clcE gene encoding the maleylacetate reductase of Pseudomonas sp. strain B13." Kasberg T., Seibert V., Schlomann M., Reineke W. J. Bacteriol. 179:3801-3803(1997) [PubMed: 9171435] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF019038 Genomic DNA. Translation: AAB71540.1.
3D structure databases
ProteinModelPortal	O30847.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-14383.
Family and domain databases
InterPro	IPR001670. ADH_Fe. [Graphical view]
Pfam	PF00465. Fe-ADH. 1 hit. [Graphical view]
PROSITE	PS00913. ADH_IRON_1. False negative. PS00060. ADH_IRON_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CLCE_PSESB

Accession

Primary (citable) accession number: O30847

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	January 1, 1998
Last modified:	September 21, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program