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O30826 (SODM_HAEDU) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Mn]

EC=1.15.1.1
Gene names
Name:sodA
Ordered Locus Names:HD_0321
OrganismHaemophilus ducreyi (strain 35000HP / ATCC 700724) [Complete proteome] [HAMAP]
Taxonomic identifier233412 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Enzyme regulation

Inhibited by hydrogen peroxide.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
   LigandManganese
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 213212Superoxide dismutase [Mn]
PRO_0000160039

Sites

Metal binding271Manganese By similarity
Metal binding821Manganese By similarity
Metal binding1681Manganese By similarity
Metal binding1721Manganese By similarity

Experimental info

Sequence conflict1111E → K in AAC46219. Ref.1

Sequences

Sequence LengthMass (Da)Tools
O30826 [UniParc].

Last modified January 23, 2007. Version 4.
Checksum: 3CE142A1B032E458

FASTA21324,107
        10         20         30         40         50         60 
MTYQLPELGY AYDALEPYFD KETMEIHHSK HHQAYVNNSN ALLEKHPELL EKCPGALLKD 

        70         80         90        100        110        120 
LTQVPAEKRT AVRNNLGGHV NHTLFWKGLK TGTTLQGALK DAIIRDFGSV EAFQAEFEQA 

       130        140        150        160        170        180 
AATRFGSGWA WLVLEEGKLA VVSTANQDSP IMGKDVAGVS GYPIFTLDVW EHAYYLHYQN 

       190        200        210 
RRPDYIKAFW NVVNWDEASR RFEEKQAGCG CTK 

« Hide

References

« Hide 'large scale' references
[1]"The sodA gene of Haemophilus ducreyi encodes a hydrogen peroxide-inhibitable superoxide dismutase."
San Mateo L.R., Toffer K.L., Kawula T.H.
Gene 207:251-257(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 35000HP / ATCC 700724.
[2]"The complete genome sequence of Haemophilus ducreyi."
Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 35000HP / ATCC 700724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF017750 Genomic DNA. Translation: AAC46219.1.
AE017143 Genomic DNA. Translation: AAP95298.1.
PIRJC6542.
RefSeqNP_872909.1. NC_002940.2.

3D structure databases

ProteinModelPortalO30826.
SMRO30826. Positions 2-206.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233412.HD0321.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP95298; AAP95298; HD_0321.
GeneID1490327.
KEGGhdu:HD0321.
PATRIC20177209. VBIHaeDuc133973_0263.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0605.
KOK04564.
OMAPLPYDYN.
OrthoDBEOG63NMNT.

Enzyme and pathway databases

BioCycHDUC233412:GH5F-305-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSODM_HAEDU
AccessionPrimary (citable) accession number: O30826
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 99 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families