SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O30826

- SODM_HAEDU

UniProt

O30826 - SODM_HAEDU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Superoxide dismutase [Mn]
Gene
sodA, HD_0321
Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Enzyme regulationi

Inhibited by hydrogen peroxide.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi27 – 271Manganese By similarity
Metal bindingi82 – 821Manganese By similarity
Metal bindingi168 – 1681Manganese By similarity
Metal bindingi172 – 1721Manganese By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciHDUC233412:GH5F-305-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Mn] (EC:1.15.1.1)
    Gene namesi
    Name:sodA
    Ordered Locus Names:HD_0321
    OrganismiHaemophilus ducreyi (strain 35000HP / ATCC 700724)
    Taxonomic identifieri233412 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000001022: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed By similarity
    Chaini2 – 213212Superoxide dismutase [Mn]
    PRO_0000160039Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer By similarity.

    Protein-protein interaction databases

    STRINGi233412.HD0321.

    Structurei

    3D structure databases

    ProteinModelPortaliO30826.
    SMRiO30826. Positions 2-206.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0605.
    KOiK04564.
    OMAiPLPYDYN.
    OrthoDBiEOG63NMNT.

    Family and domain databases

    InterProiIPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view]
    PANTHERiPTHR11404. PTHR11404. 1 hit.
    PfamiPF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000349. SODismutase. 1 hit.
    PRINTSiPR01703. MNSODISMTASE.
    SUPFAMiSSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEiPS00088. SOD_MN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O30826-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTYQLPELGY AYDALEPYFD KETMEIHHSK HHQAYVNNSN ALLEKHPELL    50
    EKCPGALLKD LTQVPAEKRT AVRNNLGGHV NHTLFWKGLK TGTTLQGALK 100
    DAIIRDFGSV EAFQAEFEQA AATRFGSGWA WLVLEEGKLA VVSTANQDSP 150
    IMGKDVAGVS GYPIFTLDVW EHAYYLHYQN RRPDYIKAFW NVVNWDEASR 200
    RFEEKQAGCG CTK 213
    Length:213
    Mass (Da):24,107
    Last modified:January 23, 2007 - v4
    Checksum:i3CE142A1B032E458
    GO

    Sequence conflict

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti111 – 1111E → K in AAC46219. 1 Publication

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF017750 Genomic DNA. Translation: AAC46219.1.
    AE017143 Genomic DNA. Translation: AAP95298.1.
    PIRiJC6542.
    RefSeqiNP_872909.1. NC_002940.2.

    Genome annotation databases

    EnsemblBacteriaiAAP95298; AAP95298; HD_0321.
    GeneIDi1490327.
    KEGGihdu:HD0321.
    PATRICi20177209. VBIHaeDuc133973_0263.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF017750 Genomic DNA. Translation: AAC46219.1 .
    AE017143 Genomic DNA. Translation: AAP95298.1 .
    PIRi JC6542.
    RefSeqi NP_872909.1. NC_002940.2.

    3D structure databases

    ProteinModelPortali O30826.
    SMRi O30826. Positions 2-206.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 233412.HD0321.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP95298 ; AAP95298 ; HD_0321 .
    GeneIDi 1490327.
    KEGGi hdu:HD0321.
    PATRICi 20177209. VBIHaeDuc133973_0263.

    Phylogenomic databases

    eggNOGi COG0605.
    KOi K04564.
    OMAi PLPYDYN.
    OrthoDBi EOG63NMNT.

    Enzyme and pathway databases

    BioCyci HDUC233412:GH5F-305-MONOMER.

    Family and domain databases

    InterProi IPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view ]
    PANTHERi PTHR11404. PTHR11404. 1 hit.
    Pfami PF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000349. SODismutase. 1 hit.
    PRINTSi PR01703. MNSODISMTASE.
    SUPFAMi SSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEi PS00088. SOD_MN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "The sodA gene of Haemophilus ducreyi encodes a hydrogen peroxide-inhibitable superoxide dismutase."
      San Mateo L.R., Toffer K.L., Kawula T.H.
      Gene 207:251-257(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 35000HP / ATCC 700724.
    2. "The complete genome sequence of Haemophilus ducreyi."
      Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 35000HP / ATCC 700724.

    Entry informationi

    Entry nameiSODM_HAEDU
    AccessioniPrimary (citable) accession number: O30826
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: January 23, 2007
    Last modified: July 9, 2014
    This is version 99 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

    Similar proteinsi