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Protein

Superoxide dismutase [Mn]

Gene

sodA

Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Enzyme regulationi

Inhibited by hydrogen peroxide.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27ManganeseBy similarity1
Metal bindingi82ManganeseBy similarity1
Metal bindingi168ManganeseBy similarity1
Metal bindingi172ManganeseBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn] (EC:1.15.1.1)
Gene namesi
Name:sodA
Ordered Locus Names:HD_0321
OrganismiHaemophilus ducreyi (strain 35000HP / ATCC 700724)
Taxonomic identifieri233412 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000001022 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001600392 – 213Superoxide dismutase [Mn]Add BLAST212

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi233412.HD0321

Structurei

3D structure databases

ProteinModelPortaliO30826
SMRiO30826
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4 Bacteria
COG0605 LUCA
KOiK04564
OMAiYEGWKGE
OrthoDBiPOG091H03Q7

Family and domain databases

Gene3Di1.10.287.9901 hit
2.40.500.201 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O30826-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTYQLPELGY AYDALEPYFD KETMEIHHSK HHQAYVNNSN ALLEKHPELL
60 70 80 90 100
EKCPGALLKD LTQVPAEKRT AVRNNLGGHV NHTLFWKGLK TGTTLQGALK
110 120 130 140 150
DAIIRDFGSV EAFQAEFEQA AATRFGSGWA WLVLEEGKLA VVSTANQDSP
160 170 180 190 200
IMGKDVAGVS GYPIFTLDVW EHAYYLHYQN RRPDYIKAFW NVVNWDEASR
210
RFEEKQAGCG CTK
Length:213
Mass (Da):24,107
Last modified:January 23, 2007 - v4
Checksum:i3CE142A1B032E458
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti111E → K in AAC46219 (PubMed:9511768).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF017750 Genomic DNA Translation: AAC46219.1
AE017143 Genomic DNA Translation: AAP95298.1
PIRiJC6542
RefSeqiWP_010944351.1, NC_002940.2

Genome annotation databases

EnsemblBacteriaiAAP95298; AAP95298; HD_0321
GeneIDi24944925
KEGGihdu:HD_0321

Similar proteinsi

Entry informationi

Entry nameiSODM_HAEDU
AccessioniPrimary (citable) accession number: O30826
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 119 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome