ID   DADA_KLEAE              Reviewed;         432 AA.
AC   O30745;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   20-JAN-2009, entry version 44.
DE   RecName: Full=D-amino acid dehydrogenase small subunit;
DE            EC=1.4.99.1;
GN   Name=dadA;
OS   Klebsiella aerogenes.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=28451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=W70;
RX   MEDLINE=98117036; PubMed=9457858;
RA   Janes B.K., Bender R.A.;
RT   "Alanine catabolism in Klebsiella aerogenes: molecular
RT   characterization of the dadAB operon and its regulation by the
RT   nitrogen assimilation control protein.";
RL   J. Bacteriol. 180:563-570(1998).
CC   -!- FUNCTION: Oxidative deamination of D-amino acids.
CC   -!- CATALYTIC ACTIVITY: A D-amino acid + H(2)O + acceptor = a 2-oxo
CC       acid + NH(3) + reduced acceptor.
CC   -!- COFACTOR: FAD (By similarity).
CC   -!- PATHWAY: Amino-acid degradation; D-alanine degradation; NH(3) and
CC       pyruvate from D-alanine: step 1/1.
CC   -!- SUBUNIT: Heterodimer of a small and a large subunit (By
CC       similarity).
CC   -!- INDUCTION: By alanine; slightly repressed by glucose.
CC   -!- SIMILARITY: Belongs to the dadA oxidoreductase family.
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DR   EMBL; AF016253; AAC38139.1; -; Genomic_DNA.
DR   BRENDA; 1.4.99.1; 366.
DR   GO; GO:0008718; F:D-amino-acid dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0006524; P:alanine catabolic process; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_01202; -; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   Pfam; PF01266; DAO; 1.
DR   ProDom; PD000139; FAD_pyr_redox; 1.
PE   2: Evidence at transcript level;
KW   FAD; Flavoprotein; Oxidoreductase.
FT   CHAIN         1    432       D-amino acid dehydrogenase small subunit.
FT                                /FTId=PRO_0000166134.
FT   NP_BIND       3     17       FAD (Potential).
SQ   SEQUENCE   432 AA;  47251 MW;  096986F47BDB4DD6 CRC64;
     MRVVILGSGV FGVASAWYLS QAGHDVTVID RQPGPAEETS AANAGQISPG YAAPWAAPGV
     PLKAIKWMFQ RHAPLAIGLD GTSFQLKWMW QMLRNCDTRH YMENKGRMVR LAEYSRDCLK
     ALRDTTGIQY EGRQGGTLQL FRTAKQYENA TRDIAVLEDA GVPYQLLEAK RLAEVEPALA
     EVSHKLTGGL RLPNDETGDC QLFTTRLAAM ADQAGVTFRF NTAVDALLHE GDRIAGVKCG
     MRIIKGDAYV MAFGSYSTAM LKGLVDIPVY PLKGYSLTIP IAQEDGAPVS TILDVTYTIA
     ITRFDQRIRV GGMAEIVGFN KTLLQPRRET LEMVVRDLFP RGGHVEQATF WTGLRPMTPD
     GTPVVGRTAY KNLWLNTGHG TLGWTMACGS GQLISDLISG RTPAIPYDDL AVARYSPGFT
     PARPQHLHGA HN
//