O30511 (O30511_HELPX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alpha1,3-fucosyltransferase EMBL AAB81031.1

Gene names

Name:

fucT EMBL AAB81031.1

Organism

Helicobacter pylori (Campylobacter pylori) EMBL AAB81031.1

Taxonomic identifier

210 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	478 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Glycosyltransferase EMBL AAB81031.1 Transferase
Technical term	3D-structure PDB 2NZY PDB 2NZW PDB 2NZX
Gene Ontology (GO)
Biological process	protein glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	fucosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	246 – 249	4	Fucose binding PDB 2NZY
Sites
	Binding site	94	1	Fucose; via carbonyl oxygen PDB 2NZY
	Binding site	240	1	Fucose PDB 2NZY

Sequences

	Sequence		Length	Mass (Da)
	O30511 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: ACD47A9C7D2D3266	FASTA	478	56,070
	10 20 30 40 50 60 MFQPLLDAYV ESASIEKMAS KSPPPLKIAV ANWWGDEEIK EFKNSVLYFI LSQRYTITLH 70 80 90 100 110 120 QNPNEFSDLV FGNPLGSARK ILSYQNAKRV FYTGENESPN FNLFDYAIGF DELDFNDRYL 130 140 150 160 170 180 RMPLYYDRLH HKAESVNDTT APYKLKDNSL YALKKPSHCF KEKHPNLCAV VNDESDPLKR 190 200 210 220 230 240 GFASFVASNP NAPIRNAFYD ALNSIEPVTG GGSVRNTLGY NVKNKNEFLS QYKFNLCFEN 250 260 270 280 290 300 TQGYGYVTEK IIDAYFSHTI PIYWGSPSVA KDFNPKSFVN VHDFKNFDEA IDYIKYLHTH 310 320 330 340 350 360 KNAYLDMLYE NPLNTLDGKA YFYQNLSFKK ILAFFKTILE NDTIYHDNPF IFCRDLNEPL 370 380 390 400 410 420 VTIDDLRVNY DDLRVNYDDL RINYDDLRVN YDDLRINYDD LRVNYDDLRV NYDDLRINYD 430 440 450 460 470 DLRVNYDDLR VNYERLLSKA TPLLELSQNT TSKIYRKAYQ KSLPLLRAIR RWVKKLGL

References

[1]	"Cloning and heterologous expression of an alpha1,3-fucosyltransferase gene from the gastric pathogen Helicobacter pylori." Ge Z., Chan N.W., Palcic M.M., Taylor D.E. J. Biol. Chem. 272:21357-21363(1997) [PubMed: 9261149] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NCTC 11639 EMBL AAB81031.1.
[2]	"Structure and mechanism of h. pylori fucosyltransferase: a basis for lipopolysaccharide variation and inhibitor design." Sun H.Y., Lin S.W., Ko T.P., Liu C.L., Wang H.J., Lin C.H. Submitted (NOV-2006) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 1-363.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF008596 Genomic DNA. Translation: AAB81031.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2NZW	X-ray	1.90	A/B/C	1-363	[»]
2NZX	X-ray	1.90	A/B/C	1-363	[»]
2NZY	X-ray	2.05	A/B/C	1-363	[»]

ProteinModelPortal

O30511.

SMR

O30511. Positions 1-351.

ModBase

Search...

Protein family/group databases

CAZy

GT10. Glycosyltransferase Family 10.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Enzyme and pathway databases

BRENDA

2.4.1.214. 1131.

Family and domain databases

InterPro

IPR016646. Alpha-1_3/4-FUT_helico.
IPR001503. Glyco_trans_10.
[Graphical view]

PANTHER

PTHR11929. Glyco_trans_10. 1 hit.

Pfam

PF00852. Glyco_transf_10. 1 hit.
[Graphical view]

PIRSF

PIRSF016150. Alpha1_3/4FUT_helico. 1 hit.

ProtoNet

Search...

Entry information

Entry name

O30511_HELPX

Accession

Primary (citable) accession number: O30511

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)