O30372 (PVCC_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pyoverdin chromophore biosynthetic protein PvcC

Gene names

Name:	pvcC
Ordered Locus Names:	PA2256

Organism

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]

Taxonomic identifier

208964 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa group › Pseudomonas aeruginosa

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	FAD By similarity.
Pathway	Siderophore biosynthesis; pyoverdin biosynthesis.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	pyoverdine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	acyl-CoA dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Pyoverdin chromophore biosynthetic protein PvcC		PRO_0000097117
Experimental info
	Sequence conflict	146	1	L → F in AAC21673. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	O30372 [UniParc]. Last modified December 8, 2000. Version 2. Checksum: 15612EB86C03EBBE	FASTA	500	55,778
	10 20 30 40 50 60 MSHSVPNALM TGADYLDSLR DGRQVYLNGE RVADVTRHRA FRNACRSIAG LYDGLHGEQR 70 80 90 100 110 120 DVLTRVDAQG RRSHRFFTPA QNAEDLLGAR EAIGCWSRMT YGFMGRTPDY KAAFMSGLEA 130 140 150 160 170 180 GAGFYGDYRH NACAWHRAFA DRGLFLNHAI INPPLDRSKA IHEMRDVFVH VERETDQGIV 190 200 210 220 230 240 VSGAKMLATG SAITNATFVA PVASAQMEAG KAEDFAVVFF ARMDNPGLRL MCRPSYEERA 250 260 270 280 290 300 SSPFDYPLSS RFDENDSVLL FDKALIPWED VLVYRDLRRA TGFYAESGFA NLYNFQSGIR 310 320 330 340 350 360 LGVKLELMIG LLSLGVRANG TQSFRGIQAA LGELIALQHL LQALTTAMAR DPERNAAGSA 370 380 390 400 410 420 VPRLEYANAL RIQVPQIWKR VRELLESALG GAPLVTVSGA ADLRDGEARR LVDSYYRGAE 430 440 450 460 470 480 LEPEQRLKLF KLIWDATGSE FGARHAVYES HYSGNAEQIR LDSLAWASRR GHLAYCEAMV 490 500 QRCMADYDIH GWLRGPWQHD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The pvc gene cluster of Pseudomonas aeruginosa: role in synthesis of the pyoverdine chromophore and regulation by PtxR and PvdS." Stintzi A., Johnson Z., Stonehouse M., Ochsner U., Meyer J.M., Vasil M.L., Poole K. J. Bacteriol. 181:4118-4124(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]	"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen." Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V. Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF002222 Genomic DNA. Translation: AAC21673.1. AE004091 Genomic DNA. Translation: AAG05644.1.
PIR	B83364.
RefSeq	NP_250946.1. NC_002516.2.
3D structure databases
ProteinModelPortal	O30372.
SMR	O30372. Positions 11-455.
ModBase	Search...
Protein-protein interaction databases
STRING	208964.PA2256.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	878263.
KEGG	pae:PA2256.
PATRIC	19838956. VBIPseAer58763_2358.
Organism-specific databases
PseudoCAP	PA2256.
Phylogenomic databases
eggNOG	COG2368.
HOGENOM	HOG000145841.
OMA	DRSKAIH.
ProtClustDB	CLSK867122.
Enzyme and pathway databases
UniPathway	UPA00019.
Family and domain databases
Gene3D	2.40.110.10. 1 hit.
InterPro	IPR006091. Acyl-CoA_Oxase/DH_cen-dom. IPR009075. AcylCo_DH/oxidase_C. IPR009100. AcylCoA_DH/oxidase. IPR024677. HpaB/PvcC. IPR004925. HpaB/PvcC/4-BUDH. IPR024719. HpaB/PvcC/4-BUDH_C. IPR024674. HpaB/PvcC/4-BUDH_N. [Graphical view]
Pfam	PF03241. HpaB. 1 hit. PF11794. HpaB_N. 1 hit. [Graphical view]
PIRSF	PIRSF500125. 4_HPA_large. 1 hit. PIRSF000331. HpaA_HpaB. 1 hit.
SUPFAM	SSF56645. AcylCoA_dehyd_NM. 1 hit. SSF47203. AcylCoADH_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PVCC_PSEAE

Accession

Primary (citable) accession number: O30372

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	December 8, 2000
Last modified:	May 1, 2013
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program