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O30297 (PPNK_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase
Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Ordered Locus Names:AF_2373
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) [Reference proteome] [HAMAP]
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus ›

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 249249Probable inorganic polyphosphate/ATP-NAD kinase HAMAP-Rule MF_00361
PRO_0000120697

Secondary structure

1 ............................................... 249
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O30297 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: E07E3163BD14FC7B

FASTA24927,868
        10         20         30         40         50         60 
MRAAVVYKTD GHVKRIEEAL KRLEVEVELF NQPSEELENF DFIVSVGGDG TILRILQKLK 

        70         80         90        100        110        120 
RCPPIFGINT GRVGLLTHAS PENFEVELKK AVEKFEVERF PRVSCSAMPD VLALNEIAVL 

       130        140        150        160        170        180 
SRKPAKMIDV ALRVDGVEVD RIRCDGFIVA TQIGSTGYAF SAGGPVVEPY LECFILIPIA 

       190        200        210        220        230        240 
PFRFGWKPYV VSMERKIEVI AEKAIVVADG QKSVDFDGEI TIEKSEFPAV FFKNEKRFRN 


LFGKVRSIG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000782 Genomic DNA. Translation: AAB91287.1.
PIRE69546.
RefSeqNP_071196.1. NC_000917.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1SUWX-ray2.45A/B/C/D1-249[»]
1Z0SX-ray1.70A/B/C/D1-249[»]
1Z0UX-ray2.00A/B1-249[»]
1Z0ZX-ray2.85A/B/C/D1-249[»]
ProteinModelPortalO30297.
SMRO30297. Positions 1-249.
ModBaseSearch...

Protein-protein interaction databases

STRING224325.AF2373.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB91287; AAB91287; AF_2373.
GeneID1485603.
KEGGafu:AF2373.

Phylogenomic databases

eggNOGCOG0061.
KOK00858.
OMAVVDYRAD.
ProtClustDBCLSK2747294.

Enzyme and pathway databases

BioCycAFUL224325:GJBC-2422-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceO30297.

Entry information

Entry namePPNK_ARCFU
AccessionPrimary (citable) accession number: O30297
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: May 1, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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