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Protein

Molybdate/tungstate import ATP-binding protein WtpC

Gene

wtpC

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Responsible for energy coupling to the transport system (Probable).Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi31 – 38ATPCurated8

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Molybdenum, Nucleotide-binding

Protein family/group databases

TCDBi3.A.1.6.8. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Molybdate/tungstate import ATP-binding protein WtpC (EC:3.6.3.-)
Gene namesi
Name:wtpC
Synonyms:modC
Ordered Locus Names:AF_0092
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003385011 – 240Molybdate/tungstate import ATP-binding protein WtpCAdd BLAST240

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (WtpC), two transmembrane proteins (WtpB) and a solute-binding protein (WtpA).1 Publication

Protein-protein interaction databases

DIPiDIP-60272N.
STRINGi224325.AF0092.

Structurei

Secondary structure

1240
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 11Combined sources9
Beta strandi14 – 22Combined sources9
Beta strandi24 – 30Combined sources7
Helixi37 – 45Combined sources9
Beta strandi51 – 57Combined sources7
Turni67 – 69Combined sources3
Helixi87 – 92Combined sources6
Helixi100 – 112Combined sources13
Turni113 – 115Combined sources3
Turni117 – 121Combined sources5
Helixi124 – 126Combined sources3
Helixi129 – 141Combined sources13
Beta strandi146 – 152Combined sources7
Helixi159 – 176Combined sources18
Beta strandi180 – 185Combined sources6
Helixi187 – 193Combined sources7
Beta strandi195 – 201Combined sources7
Beta strandi204 – 209Combined sources6
Helixi211 – 216Combined sources6
Helixi222 – 225Combined sources4
Helixi226 – 228Combined sources3
Helixi229 – 238Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ONKX-ray3.10A/B/F/G1-240[»]
ProteinModelPortaliO30144.
SMRiO30144.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO30144.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 227ABC transporterPROSITE-ProRule annotationAdd BLAST226

Sequence similaritiesi

Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiarCOG00180. Archaea.
COG3839. LUCA.
KOiK15497.
OMAiTILFSDH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR030283. WtpC.
[Graphical view]
PANTHERiPTHR24220:SF421. PTHR24220:SF421. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O30144-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLKVRAEKR LGNFRLNVDF EMGRDYCVLL GPTGAGKSVF LELIAGIVKP
60 70 80 90 100
DRGEVRLNGA DITPLPPERR GIGFVPQDYA LFPHLSVYRN IAYGLRNVER
110 120 130 140 150
VERDRRVREM AEKLGIAHLL DRKPARLSGG ERQRVALARA LVIQPRLLLL
160 170 180 190 200
DEPLSAVDLK TKGVLMEELR FVQREFDVPI LHVTHDLIEA AMLADEVAVM
210 220 230 240
LNGRIVEKGK LKELFSAKNG EVAEFLSARN LLLKVSKILD
Length:240
Mass (Da):27,027
Last modified:January 1, 1998 - v1
Checksum:i7F81725C51B69379
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB91137.1.
PIRiD69261.
RefSeqiWP_010877606.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB91137; AAB91137; AF_0092.
GeneIDi1483304.
KEGGiafu:AF_0092.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB91137.1.
PIRiD69261.
RefSeqiWP_010877606.1. NC_000917.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ONKX-ray3.10A/B/F/G1-240[»]
ProteinModelPortaliO30144.
SMRiO30144.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60272N.
STRINGi224325.AF0092.

Protein family/group databases

TCDBi3.A.1.6.8. the atp-binding cassette (abc) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB91137; AAB91137; AF_0092.
GeneIDi1483304.
KEGGiafu:AF_0092.

Phylogenomic databases

eggNOGiarCOG00180. Archaea.
COG3839. LUCA.
KOiK15497.
OMAiTILFSDH.

Miscellaneous databases

EvolutionaryTraceiO30144.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR030283. WtpC.
[Graphical view]
PANTHERiPTHR24220:SF421. PTHR24220:SF421. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiWTPC_ARCFU
AccessioniPrimary (citable) accession number: O30144
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.