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Protein

Molybdate/tungstate import ATP-binding protein WtpC

Gene

wtpC

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Responsible for energy coupling to the transport system (Probable).Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi31 – 38ATPCurated8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processTransport
LigandATP-binding, Molybdenum, Nucleotide-binding

Enzyme and pathway databases

BioCyciAFUL224325:G1G17-93-MONOMER

Protein family/group databases

TCDBi3.A.1.6.8 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Molybdate/tungstate import ATP-binding protein WtpC (EC:3.6.3.-)
Gene namesi
Name:wtpC
Synonyms:modC
Ordered Locus Names:AF_0092
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003385011 – 240Molybdate/tungstate import ATP-binding protein WtpCAdd BLAST240

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (WtpC), two transmembrane proteins (WtpB) and a solute-binding protein (WtpA).1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
wtpBO301432EBI-15624339,EBI-15624357

Protein-protein interaction databases

DIPiDIP-60272N
IntActiO30144, 2 interactors
STRINGi224325.AF0092

Structurei

Secondary structure

1240
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 11Combined sources9
Beta strandi14 – 22Combined sources9
Beta strandi24 – 30Combined sources7
Helixi37 – 45Combined sources9
Beta strandi51 – 57Combined sources7
Turni67 – 69Combined sources3
Helixi87 – 92Combined sources6
Helixi100 – 112Combined sources13
Turni113 – 115Combined sources3
Turni117 – 121Combined sources5
Helixi124 – 126Combined sources3
Helixi129 – 141Combined sources13
Beta strandi146 – 152Combined sources7
Helixi159 – 176Combined sources18
Beta strandi180 – 185Combined sources6
Helixi187 – 193Combined sources7
Beta strandi195 – 201Combined sources7
Beta strandi204 – 209Combined sources6
Helixi211 – 216Combined sources6
Helixi222 – 225Combined sources4
Helixi226 – 228Combined sources3
Helixi229 – 238Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ONKX-ray3.10A/B/F/G1-240[»]
ProteinModelPortaliO30144
SMRiO30144
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO30144

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 227ABC transporterPROSITE-ProRule annotationAdd BLAST226

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG00180 Archaea
COG3839 LUCA
KOiK15497
OMAiNCEFVAR
OrthoDBiPOG093Z02V6

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
IPR030283 WtpC
PANTHERiPTHR42781:SF2 PTHR42781:SF2, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

O30144-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLKVRAEKR LGNFRLNVDF EMGRDYCVLL GPTGAGKSVF LELIAGIVKP
60 70 80 90 100
DRGEVRLNGA DITPLPPERR GIGFVPQDYA LFPHLSVYRN IAYGLRNVER
110 120 130 140 150
VERDRRVREM AEKLGIAHLL DRKPARLSGG ERQRVALARA LVIQPRLLLL
160 170 180 190 200
DEPLSAVDLK TKGVLMEELR FVQREFDVPI LHVTHDLIEA AMLADEVAVM
210 220 230 240
LNGRIVEKGK LKELFSAKNG EVAEFLSARN LLLKVSKILD
Length:240
Mass (Da):27,027
Last modified:January 1, 1998 - v1
Checksum:i7F81725C51B69379
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA Translation: AAB91137.1
PIRiD69261
RefSeqiWP_010877606.1, NC_000917.1

Genome annotation databases

EnsemblBacteriaiAAB91137; AAB91137; AF_0092
GeneIDi1483304
KEGGiafu:AF_0092

Similar proteinsi

Entry informationi

Entry nameiWTPC_ARCFU
AccessioniPrimary (citable) accession number: O30144
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: January 1, 1998
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health