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Protein

Molybdate/tungstate transport system permease protein WtpB

Gene

wtpB

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane (Probable).Curated

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Molybdenum

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-97-MONOMER.

Protein family/group databases

TCDBi3.A.1.6.8. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Molybdate/tungstate transport system permease protein WtpB
Gene namesi
Name:wtpB
Synonyms:modB
Ordered Locus Names:AF_0093
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 22Cytoplasmic1 Publication
Transmembranei3 – 2826Helical; Name=1Add
BLAST
Topological domaini29 – 4618Extracellular1 PublicationAdd
BLAST
Transmembranei47 – 7630Helical; Name=2Add
BLAST
Topological domaini77 – 859Cytoplasmic1 Publication
Transmembranei86 – 11025Helical; Name=3Add
BLAST
Topological domaini111 – 12313Extracellular1 PublicationAdd
BLAST
Transmembranei124 – 15431Helical; Name=4Add
BLAST
Topological domaini155 – 18430Cytoplasmic1 PublicationAdd
BLAST
Transmembranei185 – 20925Helical; Name=5Add
BLAST
Topological domaini210 – 23021Extracellular1 PublicationAdd
BLAST
Transmembranei231 – 25121Helical; Name=6Add
BLAST
Topological domaini252 – 26110Cytoplasmic1 Publication

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 261261Molybdate/tungstate transport system permease protein WtpBPRO_0000338496Add
BLAST

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (WtpC), two transmembrane proteins (WtpB) and a solute-binding protein (WtpA).1 Publication

Protein-protein interaction databases

DIPiDIP-60273N.
STRINGi224325.AF0093.

Structurei

Secondary structure

1
261
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi2 – 2928Combined sources
Turni30 – 345Combined sources
Helixi35 – 439Combined sources
Helixi45 – 7733Combined sources
Helixi84 – 9613Combined sources
Helixi99 – 11012Combined sources
Turni115 – 1195Combined sources
Helixi128 – 15326Combined sources
Helixi156 – 1649Combined sources
Helixi169 – 1757Combined sources
Helixi177 – 19822Combined sources
Helixi201 – 2044Combined sources
Helixi213 – 22412Combined sources
Helixi226 – 2283Combined sources
Helixi230 – 24920Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2ONKX-ray3.10C/D/H/I1-261[»]
ProteinModelPortaliO30143.
SMRiO30143. Positions 1-252.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO30143.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini51 – 247197ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni93 – 10715Gate 1Add
BLAST
Regioni193 – 20311Gate 2Add
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG00164. Archaea.
COG0555. LUCA.
KOiK15496.
OMAiVDNFWGI.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O30143-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLFSALLA LLSSIILLFV LLPVAATVTL QLFNFDEFLK AASDPAVWKV
60 70 80 90 100
VLTTYYAALI STLIAVIFGT PLAYILARKS FPGKSVVEGI VDLPVVIPHT
110 120 130 140 150
VAGIALLVVF GSSGLIGSFS PLKFVDALPG IVVAMLFVSV PIYINQAKEG
160 170 180 190 200
FASVDVRLEH VARTLGSSPL RVFFTVSLPL SVRHIVAGAI MSWARGISEF
210 220 230 240 250
GAVVVIAYYP MIAPTLIYER YLSEGLSAAM PVAAILILLS LAVFVALRII
260
VGREDVSEGQ G
Length:261
Mass (Da):27,833
Last modified:January 1, 1998 - v1
Checksum:iC11342F58293B77F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB91136.1.
PIRiE69261.
RefSeqiWP_010877607.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB91136; AAB91136; AF_0093.
GeneIDi24793648.
KEGGiafu:AF_0093.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB91136.1.
PIRiE69261.
RefSeqiWP_010877607.1. NC_000917.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2ONKX-ray3.10C/D/H/I1-261[»]
ProteinModelPortaliO30143.
SMRiO30143. Positions 1-252.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60273N.
STRINGi224325.AF0093.

Protein family/group databases

TCDBi3.A.1.6.8. the atp-binding cassette (abc) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB91136; AAB91136; AF_0093.
GeneIDi24793648.
KEGGiafu:AF_0093.

Phylogenomic databases

eggNOGiarCOG00164. Archaea.
COG0555. LUCA.
KOiK15496.
OMAiVDNFWGI.

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-97-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO30143.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiWTPB_ARCFU
AccessioniPrimary (citable) accession number: O30143
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.