O30128 (Y108_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized aldolase AF_0108
EC=4.2.1.-

Gene names

Ordered Locus Names:

AF_0108

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Taxonomic identifier

224325 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the DeoC/FbaB aldolase family.

Ontologies

Keywords
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 265	265	Uncharacterized aldolase AF_0108		PRO_0000138953
Sites
	Active site	177	1	Schiff-base intermediate with substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	O30128 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 2950F9D9F9A0F870	FASTA	265	28,168
	10 20 30 40 50 60 MTKIGKKIRI ERIINRESRN TVIVPMDHGV SMGPIEGLKN LAETVNAVAE GGANAVVLHK 70 80 90 100 110 120 GVVGFGHRGY GKDVGLIIHL SASTSLAPDP NEKVLVCTVE EAIKLGADAV SVHVNVGSKT 130 140 150 160 170 180 EAYQLRKLGE ISKIAGEWGM PLLAMMYPRG DGINQFDEKA VALAARVGAE LGADIIKTNF 190 200 210 220 230 240 TGDVESFRRV VDGCPVPVVV AGGPKMGSDE DILRMVRMAM DAGARGVAIG RNIFQANNPT 250 260 KMTRAISMIV HDNADVSEAL EFLKS

References

[1]

"The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus." Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G. , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Nature 390:364-370(1997) [PubMed: 9389475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000782 Genomic DNA. Translation: AAB91123.1.
PIR	D69263.
RefSeq	NP_068949.1. NC_000917.1.
3D structure databases
ProteinModelPortal	O30128.
SMR	O30128. Positions 1-264.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1483320.
GenomeReviews	Gene locus AF_0108 in contig AE000782_GR.
KEGG	afu:AF0108.
NMPDR	fig|224325.1.peg.108.
TIGR	AF_0108.
Phylogenomic databases
HOGENOM	HBG553580.
OMA	AGGPKTN.
PhylomeDB	O30128.
ProtClustDB	PRK07226.
Enzyme and pathway databases
BioCyc	AFUL224325:AF_0108-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR010210. AroFGH_arch. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01623.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
TIGRFAMs	TIGR01949. AroFGH_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y108_ARCFU

Accession

Primary (citable) accession number: O30128

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program