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O30127

- RNP4_ARCFU

UniProt

O30127 - RNP4_ARCFU

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Protein
Ribonuclease P protein component 4
Gene
rnp4, AF_0109
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi62 – 621Zinc By similarity
Metal bindingi65 – 651Zinc By similarity
Metal bindingi87 – 871Zinc By similarity
Metal bindingi90 – 901Zinc By similarity

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-113-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 4 (EC:3.1.26.5)
Short name:
RNase P component 4
Alternative name(s):
Rpp21
Gene namesi
Name:rnp4
Ordered Locus Names:AF_0109
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
ProteomesiUP000002199: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 107107Ribonuclease P protein component 4UniRule annotation
PRO_0000153849Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits Reviewed prediction.

Protein-protein interaction databases

STRINGi224325.AF0109.

Structurei

3D structure databases

ProteinModelPortaliO30127.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2023.
KOiK03540.
OMAiVIVTCLN.

Family and domain databases

HAMAPiMF_00757. RNase_P_4.
InterProiIPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view]
PANTHERiPTHR14742. PTHR14742. 1 hit.
PfamiPF04032. Rpr2. 1 hit.
[Graphical view]
PIRSFiPIRSF004878. RNase_P_4. 1 hit.

Sequencei

Sequence statusi: Complete.

O30127-1 [UniParc]FASTAAdd to Basket

« Hide

MLRRDKKRES RIARERVFYL IKRAEEWKNI DYELARRYVE LARKIAMRYR    50
VRIPRELKAT YCKKCLYPYK AGKFRVRVRK SRVIITCLNC GFERRIPIRP 100
KRVNRKV 107
Length:107
Mass (Da):13,307
Last modified:January 1, 1998 - v1
Checksum:i3E670BA75B0ADB59
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000782 Genomic DNA. Translation: AAB91122.1.
PIRiE69263.
RefSeqiNP_068950.1. NC_000917.1.
WP_010877623.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB91122; AAB91122; AF_0109.
GeneIDi1483321.
KEGGiafu:AF0109.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000782 Genomic DNA. Translation: AAB91122.1 .
PIRi E69263.
RefSeqi NP_068950.1. NC_000917.1.
WP_010877623.1. NC_000917.1.

3D structure databases

ProteinModelPortali O30127.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224325.AF0109.

Protocols and materials databases

DNASUi 1483321.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB91122 ; AAB91122 ; AF_0109 .
GeneIDi 1483321.
KEGGi afu:AF0109.

Phylogenomic databases

eggNOGi COG2023.
KOi K03540.
OMAi VIVTCLN.

Enzyme and pathway databases

BioCyci AFUL224325:GJBC-113-MONOMER.

Family and domain databases

HAMAPi MF_00757. RNase_P_4.
InterProi IPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view ]
PANTHERi PTHR14742. PTHR14742. 1 hit.
Pfami PF04032. Rpr2. 1 hit.
[Graphical view ]
PIRSFi PIRSF004878. RNase_P_4. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus."
    Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G.
    , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.
    Nature 390:364-370(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.

Entry informationi

Entry nameiRNP4_ARCFU
AccessioniPrimary (citable) accession number: O30127
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: January 1, 1998
Last modified: September 3, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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