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Protein

Tetrathionate reductase subunit B

Gene

ttrB

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate. TtrB is probably involved in transfer of electrons from TtrC to TtrA (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi43Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi46Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi49Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi53Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi84Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi87Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi92Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi96Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi116Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi119Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi122Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi126Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi143Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi146Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi157Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi161Iron-sulfur 1 (4Fe-4S)By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tetrathionate reductase subunit B
Alternative name(s):
Tetrathionate reductase electron transport protein
Gene namesi
Name:ttrB
Ordered Locus Names:AF_0157
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_000041741729 – 207Tetrathionate reductase subunit BAdd BLAST179

Interactioni

Subunit structurei

Probably composed of three subunits: TtrA, TtrB and TtrC.By similarity

Protein-protein interaction databases

STRINGi224325.AF0157.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 634Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST30
Domaini75 – 1064Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST32
Domaini107 – 1364Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd BLAST30

Sequence similaritiesi

Contains 3 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiarCOG01500. Archaea.
COG0437. LUCA.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O30080-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLISKTLIFY QVVNIVSQKG SGKRRWKMEN GDRYVYVVDV SKCYGCLSCV
60 70 80 90 100
AACAAENNVP VGYFRTWVER YAMNGRVAFV PKICNHCDNP SCVHACPVNA
110 120 130 140 150
TYKTEEGLVL IDDEICIGCG ACIQACPYGA RFRNPVKGTA DKCTLCNHRI
160 170 180 190 200
PERLPACVES CPTSARVYGK MSDKAVKEIL SKKNAVVLKA YTGNEPHTYY

VSLTGVE
Length:207
Mass (Da):22,871
Last modified:May 16, 2012 - v2
Checksum:iB514E49EE888495B
GO

Sequence cautioni

The sequence AAB91070 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB91070.1. Different initiation.
PIRiE69269.
RefSeqiWP_048064177.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB91070; AAB91070; AF_0157.
GeneIDi24793708.
KEGGiafu:AF_0157.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB91070.1. Different initiation.
PIRiE69269.
RefSeqiWP_048064177.1. NC_000917.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224325.AF0157.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB91070; AAB91070; AF_0157.
GeneIDi24793708.
KEGGiafu:AF_0157.

Phylogenomic databases

eggNOGiarCOG01500. Archaea.
COG0437. LUCA.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTTRB_ARCFU
AccessioniPrimary (citable) accession number: O30080
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2012
Last sequence update: May 16, 2012
Last modified: November 2, 2016
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.