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O29876 (OGG1_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable N-glycosylase/DNA lyase

Including the following 2 domains:

  1. 8-oxoguanine DNA glycosylase
    EC=3.2.2.-
  2. DNA-(apurinic or apyrimidinic site) lyase
    Short name=AP lyase
    EC=4.2.99.18
Gene names
Name:ogg
Ordered Locus Names:AF_0371
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) [Reference proteome] [HAMAP]
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) By similarity. HAMAP-Rule MF_00241

Catalytic activity

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. HAMAP-Rule MF_00241

Sequence similarities

Belongs to the type-2 OGG1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Probable N-glycosylase/DNA lyase HAMAP-Rule MF_00241
PRO_0000159563

Sites

Active site1221 By similarity

Sequences

Sequence LengthMass (Da)Tools
O29876 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 3A5C033AA12F3FFB

FASTA19822,639
        10         20         30         40         50         60 
MIEKAISRRI KEFRQLGEKG EVEFDFRPFL DFSVKATIRT ELAFCISTAN SSATAGLKFQ 

        70         80         90        100        110        120 
RLLGQGVGVK EALTLAGVRF HNRKAEYIRE AFKSFKLVEK ALEAESSKAR EILLKIKGLG 

       130        140        150        160        170        180 
MKEASHFLRN VGREDVAIID RHILRWLERQ GYEVPGTMTA KKYLEVEKIL MEISEERGES 

       190 
LAEMDLRIWA EMTGKVLK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000782 Genomic DNA. Translation: AAB90876.1.
PIRC69296.
RefSeqNP_069207.1. NC_000917.1.

3D structure databases

ProteinModelPortalO29876.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224325.AF0371.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB90876; AAB90876; AF_0371.
GeneID1483586.
KEGGafu:AF0371.

Phylogenomic databases

eggNOGCOG1059.
KOK03653.
OMASEACFCI.

Enzyme and pathway databases

BioCycAFUL224325:GJBC-381-MONOMER.

Family and domain databases

Gene3D1.10.340.30. 1 hit.
HAMAPMF_00241. Ogg.
InterProIPR012092. DNA_glyclase/DNA_lyase_thermo.
IPR011257. DNA_glycosylase.
IPR003265. HhH-GPD_domain.
[Graphical view]
PfamPF00730. HhH-GPD. 1 hit.
[Graphical view]
PIRSFPIRSF005954. Thrmst_ogg. 1 hit.
SMARTSM00478. ENDO3c. 1 hit.
[Graphical view]
SUPFAMSSF48150. SSF48150. 1 hit.
ProtoNetSearch...

Entry information

Entry nameOGG1_ARCFU
AccessionPrimary (citable) accession number: O29876
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 1, 1998
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families