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Protein

TATA-box-binding protein

Gene

tbp

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-383-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding protein
Alternative name(s):
Box A-binding protein
Short name:
BAP
TATA sequence-binding protein
Short name:
TBP
TATA-box factor
Gene namesi
Name:tbp
Ordered Locus Names:AF_0373
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 183183TATA-box-binding proteinPRO_0000153998Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224325.AF0373.

Structurei

3D structure databases

ProteinModelPortaliO29874.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati8 – 84771Add
BLAST
Repeati99 – 177792Add
BLAST

Sequence similaritiesi

Belongs to the TBP family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
KOiK03120.
OMAiMESTINI.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O29874-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQDYKIKIEN VVASTQIGEN IDLNKISREI KDSEYKPKQF PGLVLRTKEP
60 70 80 90 100
KAAALVFRSG KVVCTGSKSV EDARRAVKQI VKMLKEIGIS VIDEPEVKVQ
110 120 130 140 150
NIVASADLGV DLNLNAIAIG LGLENIEYEP EQFPGLVYRL DNPRVVVLIF
160 170 180
GSGKMVVTGG KSPEDARKAV ERISEELRTL GLM
Length:183
Mass (Da):20,135
Last modified:January 1, 1998 - v1
Checksum:i255C5C05BBE3D8A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB90862.1.
PIRiE69296.
RefSeqiWP_010877880.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB90862; AAB90862; AF_0373.
GeneIDi24793912.
KEGGiafu:AF_0373.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB90862.1.
PIRiE69296.
RefSeqiWP_010877880.1. NC_000917.1.

3D structure databases

ProteinModelPortaliO29874.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224325.AF0373.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB90862; AAB90862; AF_0373.
GeneIDi24793912.
KEGGiafu:AF_0373.

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
KOiK03120.
OMAiMESTINI.

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-383-MONOMER.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTBP_ARCFU
AccessioniPrimary (citable) accession number: O29874
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.