O29870 (ACDD_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetyl-CoA decarbonylase/synthase complex subunit delta
Short name=ACDS complex subunit delta

Alternative name(s):
Corrinoid/iron-sulfur component small subunit

Gene names

Name:	cdhD
Ordered Locus Names:	AF_0377

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Taxonomic identifier

224325 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO2. Probably maintains the overall quaternary structure of the ACDS complex By similarity. HAMAP MF_01135
Subunit structure	Heterodimer of delta and gamma chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha2epsilon2)(4)-beta(8)-(gamma1delta1)8 Potential.
Sequence similarities	Belongs to the CdhD family.

Ontologies

Keywords
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	one-carbon metabolic process Inferred from electronic annotation. Source: InterPro pteridine-containing compound metabolic process Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 452	452	Acetyl-CoA decarbonylase/synthase complex subunit delta HAMAP MF_01135		PRO_0000155109

Sequences

	Sequence		Length	Mass (Da)
	O29870 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 55193972C432232A	FASTA	452	49,747
	10 20 30 40 50 60 MKKFTLEEFL DLLKKYNVEE IEGVKIEGDL EIEFEGSSID LSAIAPLYSM LSEFGNFLYH 70 80 90 100 110 120 ANMALGYLQR LSAALGIPTP FAAQPQLAPA APAAPAEVPA VEELKIPAEL VRAKFEPYKE 130 140 150 160 170 180 EYPGKIEEVV LGATKADGGT REYTVTLGGE RSLAFYTFDA PQPHLPAIAI DVFDRRPMLA 190 200 210 220 230 240 KAVRMHYEDV LDNPAEWARK CVKKFGADLV TLHLISTDPL LDDTPASEAV KVLEDVLQAV 250 260 270 280 290 300 KCPIIVGGSG NKEKDPEVLE KAAEVAEGER IMLASATLDM DWERIANAAK KYGHVVLSWT 310 320 330 340 350 360 QMDINNQKTL NRYLLKRVEM PRDSIVMDPT TAALGYGLDY AFTNMERIRI SGLKGDTDLN 370 380 390 400 410 420 FPISSGTTNA WGAREAWMVD SPIEEDTPWG PRELRGPIWE IITGLTLSLA GVDLFMMMHP 430 440 450 VAVAVLKEVF NTLGGKVSGG VADPGEWIFM EV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus." Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G. , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Nature 390:364-370(1997) [PubMed: 9389475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.
[2]	"Acetyl-CoA decarbonylase/synthase complex from Archaeoglobus fulgidus." Dai Y.R., Reed D.W., Millstein J.H., Hartzell P.L., Grahame D.A., DeMoll E. Arch. Microbiol. 169:525-529(1998) [PubMed: 9575239] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-18. Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000782 Genomic DNA. Translation: AAB90859.1.
PIR	A69297.
RefSeq	NP_069213.1. NC_000917.1.
3D structure databases
ProteinModelPortal	O29870.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1483592.
GenomeReviews	Gene locus AF_0377 in contig AE000782_GR.
KEGG	afu:AF0377.
NMPDR	fig|224325.1.peg.372.
TIGR	AF_0377.
Phylogenomic databases
HOGENOM	HBG456967.
OMA	IVMDPTT.
ProtClustDB	PRK04452.
Enzyme and pathway databases
BioCyc	AFUL224325:AF_0377-MONOMER.
Family and domain databases
HAMAP	MF_01135. CdhD. [Tree]
InterPro	IPR016041. Ac-CoA_synth_d_su_TIM-brl. IPR004486. CO_DH/Ac-CoA_synth_dsu. IPR011005. Dihydropteroate_synth-like. IPR000489. Pterin-binding. [Graphical view]
Gene3D	G3DSA:3.20.20.20. Dhdropt_synth. 1 hit.
KO	K00194.
Pfam	PF03599. CdhD. 1 hit. [Graphical view]
SUPFAM	SSF51717. DHP_synth_like. 1 hit.
TIGRFAMs	TIGR00381. CdhD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ACDD_ARCFU

Accession

Primary (citable) accession number: O29870

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 21, 2003
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program