O29781 (KORA_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2-oxoglutarate synthase subunit korA
EC=1.2.7.3

Alternative name(s):
2-ketoglutarate oxidoreductase alpha chain
Short name=KOR
2-oxoglutarate-ferredoxin oxidoreductase subunit alpha

Gene names

Name:	korA
Ordered Locus Names:	AF_0469

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Taxonomic identifier

224325 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-oxoglutarate + CoA + 2 oxidized ferredoxin = succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of the korA, korB, korC and korD subunits By similarity.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	2-oxoglutarate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 346	346	2-oxoglutarate synthase subunit korA		PRO_0000099937

Sequences

	Sequence		Length	Mass (Da)
	O29781 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 6D64A7CFD0D40478	FASTA	346	37,506
	10 20 30 40 50 60 MEMELIQGNE AAVRGAINAG CNFFAGYPIT PSSEIAHGMA ELLPKFGGVF IQMEDEIASI 70 80 90 100 110 120 SAVIGASMAG AVAMTATSGP GFSLMQEGMG YAAITESPVV IFNVMRAGPS TGIPTAPSQG 130 140 150 160 170 180 DAMQARYGSH GDYPIVVLAP ASVKDMYYLT VEAFKIAFRF STPVIVLSDE IVGHMRESVA 190 200 210 220 230 240 LPPLGEIESY EKRAKNLIDG RRRHRTGLVH TENGLPTTDL EEYEKLLRLL FAKFDDFRPM 250 260 270 280 290 300 VRFEGEEGVL FVAYGSSYRL AKSSAKLLAE KGVSAGILKL ESLFPFPEDA VRRYSKKADL 310 320 330 340 VVVPEMNAGQ VVKEVERVCC CRVKGVSYFG SLILPEKLVE IVEGEL

References

[1]

"The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus." Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G. , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Nature 390:364-370(1997) [PubMed: 9389475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000782 Genomic DNA. Translation: AAB90768.1.
PIR	E69308.
RefSeq	NP_069305.1. NC_000917.1.
3D structure databases
ProteinModelPortal	O29781.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1483686.
GenomeReviews	Gene locus AF_0469 in contig AE000782_GR.
KEGG	afu:AF0469.
NMPDR	fig|224325.1.peg.464.
TIGR	AF_0469.
Phylogenomic databases
HOGENOM	HBG399087.
OMA	VFVQMED.
PhylomeDB	O29781.
ProtClustDB	PRK08659.
Enzyme and pathway databases
BioCyc	AFUL224325:AF_0469-MONOMER.
Family and domain databases
InterPro	IPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N. IPR009014. Transketo_C/Pyr-ferredox_oxred. IPR015941. Transketolase-like_C. IPR005476. Transketolase_C. [Graphical view]
Gene3D	G3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KO	K00174.
Pfam	PF01855. POR_N. 1 hit. PF02780. Transketolase_C. 1 hit. [Graphical view]
SUPFAM	SSF52922. Transketo_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KORA_ARCFU

Accession

Primary (citable) accession number: O29781

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program