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O29757 (ECX1_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable exosome complex exonuclease 1
EC=3.1.13.-
Gene names
Ordered Locus Names:AF_0493
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Probably involved in the 3'->5' degradation of a variety of RNA species Potential. HAMAP MF_00591

Subunit structure

Component of the archaeal exosome multienzyme ribonuclease complex Potential.

Subcellular location

Cytoplasm Potential HAMAP MF_00591.

Sequence similarities

Belongs to the RNase PH family.

Ontologies

Keywords
   Cellular componentCytoplasm
Exosome
   Molecular functionExonuclease
Hydrolase
Nuclease
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processRNA processing

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

exosome (RNase complex)

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionRNA binding

Inferred from electronic annotation. Source: InterPro

exoribonuclease activity, producing 5'-phosphomonoesters

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258Probable exosome complex exonuclease 1 HAMAP MF_00591
PRO_0000139981

Secondary structure

1 .................................. 258
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O29757 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 592BD6A3DB2128B3

FASTA25828,847
        10         20         30         40         50         60 
MSEFNEKPEK LIVDGLRLDG RKFDELRPIK IEASVLKRAD GSCYLEMGKN KVIAAVFGPR 

        70         80         90        100        110        120 
EVHPRHLQDP SKAIIRYRYN MAPFSVEERK RPGPDRRSIE ISKVSKEAFE AVIMKELFPR 

       130        140        150        160        170        180 
SAIDIFVEVL QADAGSRTAC LNAASVALVD AGVPMKGMIT SVAVGKADGQ LVLDPMKEED 

       190        200        210        220        230        240 
NFGEADMPFA FLIRNGKIES IALLQMDGRM TRDEVKQAIE LAKKGALQIY EMQREAILRR 

       250 
YIEVGEEMDE ITEGGEDA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000782 Genomic DNA. Translation: AAB90744.1.
PIRE69311.
RefSeqNP_069329.1. NC_000917.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2BA0X-ray2.70D/E/F1-258[»]
2BA1X-ray2.70D/E/F1-258[»]
3M7NX-ray2.40D/E/F1-258[»]
3M85X-ray3.00D/E/F1-258[»]
ProteinModelPortalO29757.
SMRO29757. Positions 7-252.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1483710.
GenomeReviewsGene locus AF_0493 in contig AE000782_GR.
KEGGafu:AF0493.
NMPDRfig|224325.1.peg.488.
TIGRAF_0493.

Phylogenomic databases

HOGENOMHBG737187.
OMAHMAPFST.
PhylomeDBO29757.
ProtClustDBPRK03983.

Enzyme and pathway databases

BioCycAFUL224325:AF_0493-MONOMER.

Family and domain databases

HAMAPMF_00591. Exosome_Exonucl_1.
[Tree]
InterProIPR011807. ExoRNase_exosome_complex.
IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
KOK11600.
PfamPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMSSF55666. 3_ExoRNase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR02065. ECX1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameECX1_ARCFU
AccessionPrimary (citable) accession number: O29757
Entry history
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: January 1, 1998
Last modified: December 14, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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