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O29730 (AROK_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Shikimate kinase
Short name=SK
EC=2.7.1.71
Gene names
Name:aroK
Ordered Locus Names:AF_0520
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + shikimate = ADP + shikimate 3-phosphate. HAMAP MF_00370

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. HAMAP MF_00370

Subcellular location

Cytoplasm Probable HAMAP MF_00370.

Sequence similarities

Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

shikimate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Shikimate kinase HAMAP MF_00370
PRO_0000141571

Regions

Nucleotide binding74 – 8411ATP Potential

Sequences

Sequence LengthMass (Da)Tools
O29730 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 968F51E6FF8643D1

FASTA28030,614
        10         20         30         40         50         60 
MMRAKAYAAG TVLNALPTGI GSAFGIEMHT IVKLRPSDEL KVFVNGVERR SIVAERILNS 

        70         80         90        100        110        120 
MDVTAEVIVE SEIPGGSGLG SSSAFVNALI CAVKKMKGEE LNAFEILRSN ARFSLEAGIS 

       130        140        150        160        170        180 
YTGAFDDASA SMLGGFVVSD NRKMRLIRTD EFEGYSAVLI PKFSRGKVDW RRLRERASEV 

       190        200        210        220        230        240 
EGAVEAAMRG EYCKAMKLNT EYICKMLGYP LEIAEKGWEK GICCGISGNG PSYVAFGSKN 

       250        260        270        280 
EMEALAETWG EYGRVYVRRV ADEPAEDVVI PTPFFRKLDG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000782 Genomic DNA. Translation: AAB90713.1.
PIRH69314.
RefSeqNP_069356.1. NC_000917.1.

3D structure databases

ProteinModelPortalO29730.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1483737.
GenomeReviewsGene locus AF_0520 in contig AE000782_GR.
KEGGafu:AF0520.
NMPDRfig|224325.1.peg.515.
TIGRAF_0520.

Phylogenomic databases

HOGENOMHBG646614.
OMAMTLNGFL.
ProtClustDBCLSK2746468.

Enzyme and pathway databases

BioCycAFUL224325:AF_0520-MONOMER.

Family and domain databases

HAMAPMF_00370. Shik_kinase_arch.
[Tree]
InterProIPR006204. GHMP_kinase.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR010189. SK_arc.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00891.
PfamPF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF005758. Shikimt_kin_arch. 1 hit.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR01920. Shik_kin_archae. 1 hit.
PROSITEPS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROK_ARCFU
AccessionPrimary (citable) accession number: O29730
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: January 1, 1998
Last modified: November 16, 2011
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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