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Protein

50S ribosomal protein L7Ae

Gene

rpl7ae

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.UniRule annotation1 Publication

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP
  2. rRNA binding Source: UniProtKB-KW
  3. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. ribosome biogenesis Source: InterPro
  2. translation Source: UniProtKB-HAMAP
  3. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-780-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7AeUniRule annotation
Alternative name(s):
Ribosomal protein L8eUniRule annotation
Gene namesi
Name:rpl7aeUniRule annotation
Ordered Locus Names:AF_0764
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
ProteomesiUP000002199: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11911950S ribosomal protein L7AePRO_0000136789Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Probably part of the RNase P complex.UniRule annotation

Protein-protein interaction databases

STRINGi224325.AF0764.

Structurei

Secondary structure

1
119
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi9 – 2517Combined sources
Beta strandi26 – 316Combined sources
Helixi32 – 409Combined sources
Beta strandi45 – 528Combined sources
Helixi56 – 583Combined sources
Turni59 – 613Combined sources
Helixi62 – 687Combined sources
Beta strandi73 – 775Combined sources
Helixi79 – 857Combined sources
Beta strandi93 – 997Combined sources
Helixi101 – 1033Combined sources
Helixi104 – 11512Combined sources
Turni116 – 1183Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RLGX-ray2.70A/B1-119[»]
4BW0X-ray2.33B2-119[»]
4C4WX-ray2.95C/G2-119[»]
ProteinModelPortaliO29494.
SMRiO29494. Positions 2-118.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO29494.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L7Ae family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1358.
KOiK02936.
OMAiGIPYAYV.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
HAMAPiMF_00326. Ribosomal_L7Ae_Arch.
InterProiIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR022481. Ribosomal_L7Ae_arc.
IPR004037. Ribosomal_L7Ae_CS.
IPR000948. Ribosomal_L7Ae_prok.
[Graphical view]
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
PRINTSiPR00881. L7ARS6FAMILY.
PR00884. RIBOSOMALHS6.
SUPFAMiSSF55315. SSF55315. 1 hit.
TIGRFAMsiTIGR03677. rpl7ae. 1 hit.
PROSITEiPS01082. RIBOSOMAL_L7AE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O29494-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYVRFEVPED MQNEALSLLE KVRESGKVKK GTNETTKAVE RGLAKLVYIA
60 70 80 90 100
EDVDPPEIVA HLPLLCEEKN VPYIYVKSKN DLGRAVGIEV PCASAAIINE
110
GELRKELGSL VEKIKGLQK
Length:119
Mass (Da):13,193
Last modified:January 1, 1998 - v1
Checksum:i9065A83C82207501
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB90466.1.
PIRiD69345.
RefSeqiNP_069598.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB90466; AAB90466; AF_0764.
GeneIDi1483981.
KEGGiafu:AF0764.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB90466.1.
PIRiD69345.
RefSeqiNP_069598.1. NC_000917.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RLGX-ray2.70A/B1-119[»]
4BW0X-ray2.33B2-119[»]
4C4WX-ray2.95C/G2-119[»]
ProteinModelPortaliO29494.
SMRiO29494. Positions 2-118.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224325.AF0764.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB90466; AAB90466; AF_0764.
GeneIDi1483981.
KEGGiafu:AF0764.

Phylogenomic databases

eggNOGiCOG1358.
KOiK02936.
OMAiGIPYAYV.

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-780-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO29494.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
HAMAPiMF_00326. Ribosomal_L7Ae_Arch.
InterProiIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR022481. Ribosomal_L7Ae_arc.
IPR004037. Ribosomal_L7Ae_CS.
IPR000948. Ribosomal_L7Ae_prok.
[Graphical view]
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
PRINTSiPR00881. L7ARS6FAMILY.
PR00884. RIBOSOMALHS6.
SUPFAMiSSF55315. SSF55315. 1 hit.
TIGRFAMsiTIGR03677. rpl7ae. 1 hit.
PROSITEiPS01082. RIBOSOMAL_L7AE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus."
    Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G.
    , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.
    Nature 390:364-370(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.
  2. "Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA binding motif for C/D and H/ACA box snoRNAs in Archaea."
    Rozhdestvensky T.S., Tang T.H., Tchirkova I.V., Brosius J., Bachellerie J.-P., Huettenhofer A.
    Nucleic Acids Res. 31:869-877(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  3. "Molecular basis of box C/D RNA-protein interactions; cocrystal structure of archaeal L7Ae and a box C/D RNA."
    Moore T., Zhang Y., Fenley M.O., Li H.
    Structure 12:807-818(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS).

Entry informationi

Entry nameiRL7A_ARCFU
AccessioniPrimary (citable) accession number: O29494
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: February 4, 2015
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.