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Protein

Magnesium transport protein CorA

Gene

corA

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Mediates influx of magnesium ions.UniRule annotation

GO - Molecular functioni

  1. cobalt ion transmembrane transporter activity Source: InterPro
  2. magnesium ion transmembrane transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Ion transportUniRule annotation, Transport

Keywords - Ligandi

MagnesiumUniRule annotation

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-802-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium transport protein CorAUniRule annotation
Gene namesi
Name:corAUniRule annotation
Ordered Locus Names:AF_0786Imported
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)Imported
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
ProteomesiUP000002199: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei293 – 31321HelicalUniRule annotationAdd
BLAST
Transmembranei325 – 34521HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi224325.AF0786.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2HN1X-ray2.90A1-263[»]
ProteinModelPortaliO29472.
SMRiO29472. Positions 18-263.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO29472.

Family & Domainsi

Sequence similaritiesi

Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG0598.
KOiK03284.
OMAiEDCLEYV.

Family and domain databases

InterProiIPR004488. Mg/Co-transport_prot_CorA.
IPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
[Graphical view]
PfamiPF01544. CorA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00383. corA. 1 hit.

Sequencei

Sequence statusi: Complete.

O29472-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIPATIKKK MALPPATPVF TGEKKVEETK ITAAIYDEKS VEFKELEVGE
60 70 80 90 100
LESVVRSALA LNKKLWIDVV GVHDESLIAK ICEFLGIHPL AAEDILNTAQ
110 120 130 140 150
RVKIEDYDDH LFLVLKILLY NETLEIDQLS LVLKKNLVAT FEEREYWILD
160 170 180 190 200
SIRSRLKSGG RMRKLAGDYL AYTILDAVVD SYFEALLKIS DEIEVLEDEV
210 220 230 240 250
VSGDSTLIGK IHSLKREILA FRNAVWPLRD VLSFFTRVEH ELIGEEVKVY
260 270 280 290 300
YRDVYDHAVR LMEVLETQRE LLVSLRDLFL SAVSNKLNEI MKVLTMIATI
310 320 330 340 350
FIPLSFIAGV YGMNFKYMPE LEWKYGYPAV LTVMAVIALV MIAFFRRKGW

L
Length:351
Mass (Da):40,272
Last modified:January 1, 1998 - v1
Checksum:iE9790B12B780AC87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB90452.1.
PIRiB69348.
RefSeqiNP_069620.1. NC_000917.1.
WP_010878289.1. NC_000917.1.

Genome annotation databases

EnsemblBacteriaiAAB90452; AAB90452; AF_0786.
GeneIDi1484003.
KEGGiafu:AF0786.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA. Translation: AAB90452.1.
PIRiB69348.
RefSeqiNP_069620.1. NC_000917.1.
WP_010878289.1. NC_000917.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2HN1X-ray2.90A1-263[»]
ProteinModelPortaliO29472.
SMRiO29472. Positions 18-263.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224325.AF0786.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB90452; AAB90452; AF_0786.
GeneIDi1484003.
KEGGiafu:AF0786.

Phylogenomic databases

eggNOGiCOG0598.
KOiK03284.
OMAiEDCLEYV.

Enzyme and pathway databases

BioCyciAFUL224325:GJBC-802-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO29472.

Family and domain databases

InterProiIPR004488. Mg/Co-transport_prot_CorA.
IPR002523. MgTranspt_CorA/ZnTranspt_ZntB.
[Graphical view]
PfamiPF01544. CorA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00383. corA. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus."
    Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G.
    , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.
    Nature 390:364-370(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126Imported.
  2. "A structural basis for Mg2+ homeostasis and the CorA translocation cycle."
    Payandeh J., Pai E.F.
    EMBO J. 25:3762-3773(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 1-263.

Entry informationi

Entry nameiO29472_ARCFU
AccessioniPrimary (citable) accession number: O29472
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: March 4, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.