O29424 (O29424_ARCFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ferritin, putative EMBL AAB90406.1

Gene names

Ordered Locus Names:

AF_0834

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Taxonomic identifier

224325 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length	173 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 ferritin-like diiron domain. RuleBase RU003668

Ontologies

Keywords
Ligand	Iron PDB 1SQ3 Metal-binding PDB 1SQ3 PDB 1S3Q Zinc PDB 1S3Q
Technical term	3D-structure PDB 1SQ3 PDB 3KX9 PDB 1S3Q Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular iron ion homeostasis Inferred from electronic annotation. Source: InterPro iron ion transport Inferred from electronic annotation. Source: InterPro
Molecular function	ferric iron binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	19	1	Iron 1 PDB 1SQ3
	Metal binding	19	1	Zinc 1 PDB 1S3Q
	Metal binding	51	1	Iron 2 PDB 1SQ3
	Metal binding	52	1	Iron 1 PDB 1SQ3
	Metal binding	52	1	Iron 3 PDB 1SQ3
	Metal binding	52	1	Zinc 1 PDB 1S3Q
	Metal binding	52	1	Zinc 2 PDB 1S3Q
	Metal binding	55	1	Iron 1; via pros nitrogen PDB 1SQ3
	Metal binding	55	1	Zinc 1; via pros nitrogen PDB 1S3Q
	Metal binding	96	1	Iron 3 PDB 1SQ3
	Metal binding	96	1	Zinc 2 PDB 1S3Q
	Metal binding	128	1	Iron 2 PDB 1SQ3
	Metal binding	131	1	Iron 2 PDB 1SQ3
	Metal binding	132	1	Iron 2 PDB 1SQ3
	Metal binding	132	1	Iron 3 PDB 1SQ3
	Metal binding	132	1	Zinc 2 PDB 1S3Q

Sequences

	Sequence		Length	Mass (Da)
	O29424 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: DD55E5B59B7A30F5	FASTA	173	20,316
	10 20 30 40 50 60 MASISEKMVE ALNRQINAEI YSAYLYLSMA SYFDSIGLKG FSNWMRVQWQ EELMHAMKMF 70 80 90 100 110 120 DFVSERGGRV KLYAVEEPPS EWDSPLAAFE HVYEHEVNVT KRIHELVEMA MQEKDFATYN 130 140 150 160 170 FLQWYVAEQV EEEASALDIV EKLRLIGEDK RALLFLDKEL SLRQFTPPAE EEK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus." Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G. , Gill S.R., Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Nature 390:364-370(1997) [PubMed: 9389475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126.
[2]	"Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus." Johnson E., Cascio D., Sawaya M.R., Gingery M., Schroder I. Structure 13:637-648(2005) [PubMed: 15837202] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH IRON AND ZINC.
[3]	"Engineering a closed form of the Archaeoglobus fulgidus ferritin by site directed mutagenesis." Johnson E., Cascio D., Sawaya M.R., Lim S. Submitted (DEC-2009) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000782 Genomic DNA. Translation: AAB90406.1.

PIR

B69354.

RefSeq

NP_069668.1. NC_000917.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1S3Q	X-ray	2.10	A/B/C/D/E/F/G/H/I/J/K/L	1-173	[»]
1SQ3	X-ray	2.70	A/B/C/D/E/F/G/H/I/J/K/L	1-173	[»]
3KX9	X-ray	2.10	A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X	1-173	[»]

ProteinModelPortal

O29424.

SMR

O29424. Positions 1-164.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-48438N.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1484053.

GenomeReviews

Gene locus AF_0834 in contig AE000782_GR.

KEGG

afu:AF0834.

NMPDR

fig|224325.1.peg.827.

TIGR

AF_0834.

Phylogenomic databases

HOGENOM

HBG750128.

OMA

CEDKGFE.

PhylomeDB

O29424.

Family and domain databases

InterPro

IPR001519. Ferritin.
IPR009040. Ferritin-like.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR008331. Ferritin_DPS_dom.
[Graphical view]

Gene3D

G3DSA:1.20.1260.10. Ferritin_rel. 1 hit.

KO

K02217.

PANTHER

PTHR11431. Ferritin_N. 1 hit.

Pfam

PF00210. Ferritin. 1 hit.
[Graphical view]

SUPFAM

SSF47240. Ferritin/RR_like. 1 hit.

PROSITE

PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

O29424_ARCFU

Accession

Primary (citable) accession number: O29424

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)